Abstract:This proposal will demonstrate the feasibility of creating and formulating a dietary supplement of creatine with improved oral absorption characteristics. Such an improvement would allow increased use of creatine supplement to augment and complement existing treatments for conditions where muscle… more
Abstract:In response to Small Business Innovative Research solicitation AF01-053, 21CSI is pleased to propose the development of a proof-of-concept software decision aid for satellite command composition. Our decision aid, the Satellite Operator Decision Aid andTraining System (SODATS), will be built from… more
Abstract:21st Century Systems, Inc. proposes to research and realize agent-based decision support system under uncertainty for submarineoperations. We will use a highly innovative hybridBayesian/differential game modeling approach to tackle thisproblem. The resulting theory and technology will… more
Abstract:In response to Small Business Innovative Research solicitation OSD01-CR10, 21CSI is pleased to propose the development of a proof-of-concept software knowledge assessment tool for TPED teams. Our assessment tool, the TPED Knowledge Acquisition andAssessment System (TPED-KAAS), will be built from… more
Abstract:For efficient space operations, and for effective space force enhancement to terrestrial forces, Aerospace Operations Center (AOC) personnel must be continuously aware of the status of on-orbit assets, payload coverage, reacting to system degradations andfailures, and responding to intolerant… more
Abstract:For efficient space operations, and for effective space force enhancement to terrestrial forces, Aerospace Operations Center (AOC) personnel must be continuously aware of the status of on-orbit assets, payload coverage, reacting to system degradations andfailures, and responding to intolerant… more
Abstract:DESCRIPTION: Our goal is to develop a diagnostic assay to identify carriers of
the hereditary colon cancer (HNPCC) trait using blood samples as the input
specimen. In Phase 1 we will demonstrate the assay's feasibility, showing: 1)
requisite predictive value, 2) practicality… more
Abstract:Rural school districts face major challenges each year creating and managing school bus routes and budgeting funds to pay for increasing transportation costs. Currently, many rural schools design their school bus routes by acquiring a school district map, placing a stickpin on the where each student… more
Abstract:DESCRIPTION (provided by applicant): We are developing a new technology for
single molecule DNA sequencing based on the incorporation of dNTPs labeled on
the g-phosphate with fluorescent dyes. The label is cleaved from the nucleotide
along with pyrophosphate when the nucleotide… more
Abstract:DESCRIPTION (provided by applicant): We are developing a new technology for
single molecule DNA sequencing based on the incorporation of dNTPs labeled on
the g-phosphate with fluorescent dyes. The label is cleaved from the nucleotide
along with pyrophosphate when the nucleotide… more
Abstract:APPLICANT'S DESCRIPTION: DNA polymerases with altered substrate specificity are
needed to support a new approach to single molecule DNA sequencing. Single
molecule methods can be applied to DNA isolated directly from a subject
organism, eliminating the need to clone, map and sort DNA fragments prior… more
Abstract:The primary goal of the feasibility study proposed here is to document the effectiveness of producing free fatty acids and fatty acid esters using a system where 1) a motionless mixer is the reactor; 2) free fatty acids are the catalyst; and 3) reaction times to achieve 95+ percent yields are on the… more
Abstract:Porcine reproductive and respiratory syndrome was recognized in the U.S. in 1987 as a new infectious disease of swine causing late-term reproductive failure and severe pneumonia in neonatal pigs. The etiological agent is PRRS virus (PRRSV). Current attenuated vaccines against PRRSV are not totally… more
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