Abstract:DESCRIPTION (provided by applicant): The evaluation and selection of safe and effective pharmacotherapies for drug abuse and addiction is performed through clinical trials that rely on patients taking the studied medication at the specified time and frequency. To ensure accurate efficacy measures,… more
Abstract:We propose to combine QmagiQ's strained layer superlattice (SLS) sensor technology with MIT Lincoln Laboratory's novel digital pixel readout integrated circuit (DROIC) to realize an advanced longwave infrared digital focal plane array (DFPA) with high quantum efficiency, dynamic range, and… more
Abstract:We propose a high-performance broadband infrared focal plane array (FPA) for the Thermal Infrared Sensor (TIRS) on NASA's LANDSAT satellite. The FPA will feature a cutoff wavelength of 13 microns, operate at>55K, have a format of 640x512, quantum efficiency>30%, and will be realized… more
Abstract:Longwave infrared focal plane arrays (FPAs) based on Type-II InAs/GaSb-based strained layer superlattice (SLS) photodiodes show good performance at the current time. A key remaining challenge is the reduction of dark current, dominated by pixel surface leakage in FPAs and low minority carrier… more
Abstract:In Phase I we developed a novel infrared photodiode based on Type-II InAs/GaSb strained layer superlattices (SLS) that showed pingpong dualband action, wherein the spectral response of the diode was switched between extended midwave (~ 8 micron cutoff) and longwave (~ 10 micron cutoff) infrared by… more
Abstract:DESCRIPTION (provided by applicant): Anterior cruciate ligament (ACL) injuries are a significant problem for athletes, and women in particular. Both surgical and non-surgical treatment options exist, with the ultimate goal of regaining joint stability, knee kinematics, and quadriceps strength… more
Abstract:ABSTRACT: Solid State Scientific Corporation (SSSC) is pleased to propose the design of a multi-threat hostile fire indication (HFI) system for remotely-piloted aircraft (RPA). The HFI system consist of a wide field of view sensor head that employs small multi-spectral imagers in the short-wave… more
Abstract:"SSSC is pleased to propose the development and delivery of a Hostile Fire Indication Sensor (HFIS) based on the Phase I design concept. The resulting system will limit the number of circuit card assemblies to two: one for the short wave infrared (SWIR)
Abstract:This Small Business Innovation Research (SBIR) Phase II project proposes to develop a stretchy, disposable, textile glove intended to prevent cross-contamination with 3-log reduction against bio-pathogens in under 90 seconds. Its chlorine coating lasts for three days and unlike nitrile, latex, and… more
Abstract:DESCRIPTION (provided by applicant): There is currently no effective treatment for recurrent small-cell lung cancer (rSCLC). The objective of this project is to utilize a monoclonal antibody, Abner, to develop new, rational, and successful treatment of rSCLC. The hypothesis being tested is that an… more
Abstract:The United States and several other countries are investing in new neutron scattering facilities as well as upgrading existing ones due to their promise for fundamental and applied research that can catalyze advances in energy, telecommunications, manufacturing, plastics, transportation,… more
Abstract:DESCRIPTION (provided by applicant): New clinical guidelines for the treatment of exacerbations in cystic fibrosis (CF) were recently published by the American Thoracic Society. Examples of these evidence-based recommendations include not performing synergy testing to combat multi-drug-resistant… more
Abstract:DESCRIPTION (provided by applicant): Assessment of lung function in neonates and infants Lung disease is the most common chronic disease of childhood, but methods for assessing lung disease such as spirometry cannot be performed by young children. Thus clinicians have only parental reports of… more
Abstract:DESCRIPTION (provided by applicant): Roughly one million Americans with inadequately controlled severe persistent asthma have a particularly high risk of exacerbations, hospitalizations, and death, and account for a per-patient health care burden exceeding12,000 annually. Bronchial thermoplasty (BT)… more
Abstract:This Small Business Innovation Research Phase I project will investigate the development of performance bio-based latex from alkyl itaconates for application in wood coatings. Identified by DOE in 2004 as a top 12 renewable chemical, itaconic acid and its derivatives have potential use in polymers… more
Abstract:Datacenters house server farms that perform many different jobs ranging from search engines to supercomputing. In aggregate these computer systems already consume enormous power, and their energy requirements are increasing both in absolute terms and in proportion to the total capacity of the… more
Abstract:Coal-fired integrated gasification combined-cycle (IGCC) power plants need to be able to increase their power outputs during peak demand periods without increasing CO2 emissions to improve power grid quality and increase power grid security. We propose to develop a compact, low-cost… more
Abstract:Tantalum alloy and silicon nitride gun barrel liners have demonstrated excellent corrosion resistance and wear characteristics for U.S. Army applications. The quality and accuracy of the rifling profile is critical; however, the processes and tooling needed to successfully rifle a gun barrel made… more
Abstract:The objective of the Phase I project is to prove the feasibility of the Automated Naloxone Delivery System (ANDS) by: (1) designing the physiological monitoring and prediction algorithm used to trigger the injection; (2) designing and developing prototypesof the automated naloxone injection system;… more
Abstract:The objective of this proposal is to develop, implement and evaluate a set of accurate and robust algorithms specifically designed to capture and measure multilateral social interactions automatically through audio-based methods based on asymmetric data design. We propose to accomplish this by: 1)… more
Abstract:DESCRIPTION (provided by applicant): The immune system depends upon an exquisite balance between positive and negative signals to maintain proper function. However, disruptions of this balance can lead to inappropriate responses: for example loss of negative regulation can result in autoimmunity.… more
Abstract:This Small Business Innovation Research Phase I project will develop a silicon solar cell with unique junction design that provides synergistic benefits as the thickness of the solar cell is reduced. Thin silicon solar cells are currently the subject of intense interest because, in comparison to… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will demonstrate the technical and commercial viability of a high-brightness ultraviolet light-emitting diode (UVLED) system for inducing an involuntary avoidance response of birds and bats. The purpose of this system is to reduce the… more
Abstract:There is a need for developing a new generation of lightweight, rapidly deployable semi-permanent infrastructure to support the Armys transition to a Modular Force. Existing metal frame and airbeam designs, notwithstanding their many innovations, fail to take full advantage of the weight savings… more
Abstract:This technology introduces a new non-invasive, biopsy-adjunct with a MNP platform for targeted tumor delivery. It employs closely sized magnetic nanoparticles (CS-MNP's) for determining their concentration and spatial distribution in tumor vasculatures asmeasured by magnetic resonance imaging… more
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