Abstract:DESCRIPTION (provided by applicant): We have discovered, characterized and functionally defined a novel, immune inhibitory ligand. This ligand is hematopoietically-expressed, a distant member of the B7 Ig-superfamily, and its extracellular domain bears homology to the B7 family ligand PD-L1. This… more
Abstract:DESCRIPTION (provided by applicant): ImmuRx is developing a novel and potent immunotherapeutic product to stimulate the immune system. This will significantly increase the efficacy of existing and new therapeutic vaccines for the treatment of cancers suchas melanoma, lymphoma and lung cancer and… more
Abstract:The objective of this program is to develop and produce a prototype SM-3, Block IIB nosecone that can achieve all of the performance requirements specified for the IIB interceptor, but at a considerably lower cost and weight than has been achieved previously with SM-3 nosecones. This is achievable… more
Abstract:NASA's future science missions to investigate the structure and evolution of the universe require highly efficient, very low temperature coolers for low noise detector systems. We propose to develop a highly efficient, lightweight Active Magnetic Regenerative Refrigeration (AMRR) system that… more
Abstract:Future manned space exploration missions will require space suits with capabilities beyond the current state of the art. Portable Life Support Systems for these future space suits face daunting challenges, since they must maintain healthy and comfortable conditions inside the suit for long-duration… more
Abstract:For a number of years Creare has developed, fabricated, and tested highly miniaturized, high vacuum pumps specifically designed for mass spectrometers used on NASA Mars missions. These pumps would also be useful on other missions to planets and satellites with atmosphere, such as Titan, as well as… more
Abstract:Future NASA space missions require advanced systems to convert thermal energy into electric power. These systems must be reliable, efficient, and lightweight. In response, we propose to develop an intercooled turbo-Brayton power converter with high efficiency and specific power. The converter… more
Abstract:Future NASA Space Science Missions will incorporate detectors, sensors, shields, and telescopes that must be cooled to cryogenic temperatures. An enabling technology for these missions is advanced cryocoolers that can provide continuous and distributed cooling with minimal input power. On this… more
Abstract:In situ resource utilization (ISRU) is essential for several of NASA's future flagship missions. Currently envisioned ISRU plants include production of oxygen from hydrogen reduction of lunar regolith and extraction of water from Martian regolith or asteroid material. These ISRU processes… more
Abstract:Environmental control systems for manned exploration spacecraft and lunar/planetary bases will need a condensing heat exchanger (CHX) to control humidity in crew habitat modules. Antimicrobial coatings are needed to prevent growth of microbes and formation of biofilms on the condensing surfaces… more
Abstract:This proposal is responsive to NASA SBIR Topic X10.01, specifically, the need for efficient small- to medium-scale hydrogen liquefaction technologies including domestically produced wet cryogenic turboexpanders. Future NASA missions will require hydrogen liquefaction systems for earth-based,… more
Abstract:Mobile production of electric power requires generators that are compact, lightweight, efficient, and reliable. Although standard generator approaches that use radial magnetic fields are very mature, they are also larger and heavier than desired. In response, we propose to develop an axial-flux… more
Abstract:ABSTRACT: Airborne directed energy weapons offer advantages over conventional weapons as they minimize collateral damage, reducing the cost of post-conflict reconstruction. However, the high power levels required by these weapons present size and weight challenges for airborne applications. In… more
Abstract:For the U.S. Navy, Creare is developing a Compact Swaging Machine (CSM) to attach arresting gear Purchase Cable terminals on ship. Our CSM utilizes three innovative features to dramatically reduce the size and weight of the swaging machine to make it usable in a shipboard environment: (1) a high… more
Abstract:Future military communication systems will rely on advanced superconductor digital electronics. These electronics will require efficient cooling at low temperatures near 4 K. Pulse-tube cryocoolers are a candidate cooling technology for this application. We propose to improve the efficiency of the… more
Abstract:The performance of modern combustion systems used in propulsion devices (such as gas turbine main combustors, augmentors, and rockets) is largely dependent on the mixing of fuel and oxidizer. This mixing process, often involving a liquid jet emanating into a gaseous flow followed by subsequent… more
Abstract:Extremely Efficient Nebulizer for Intranasal Vaccination. Specifically the nasal delivery device could reduce health care associated infections by providing a needle-free method of delivery of vaccines and therapeutics which are currently delivered by injection with all the attendant risks of… more
Abstract:We propose to develop a large-format 1Kx1K longwave infrared focal plane array (FPA) from Type-II InAs/(In)GaSb strained layer superlattice (SLS) photodiodes. In Phase I, we will develop small pixels with the goals of ~ 10 micron cutoff wavelength, quantum efficiency>60%, and dark current… more
Abstract:We propose to bandgap engineer the InAs/GaSb/AlSb material system to realize a dualband focal plane array (FPA) made up of stacked multi-barrier Type-II strained layer superlattice (SLS) photodiodes. Two longwave infrared spectral bands will be imaged in alternate frames by using a readout… more
Abstract:We propose to develop and deliver 2-Color midwave/longwave infrared focal plane arrays (FPAs) and a camera based on Type-II InAs/InGaSb strained layer superlattice (SLS) sensor technology. 2-Color SLS FPAs with formats of 320x256 and 640x512 will be delivered, together with a portable 2-Color… more
Abstract:In Phase I, we developed a novel infrared photodiode based on Type-II InAs/GaSb strained layer superlattices (SLS) which demonstrated pingpong dualband action, wherein the spectral response of the diode was switched between midwave (~ 5 micron cutoff) and longwave (~ 10 micron cutoff) infrared by… more
Abstract:SPAWAR requires a high fidelity simulation of Radio Security Services (RSS) to enhance testing of Joint Tactical Radio System (JTRS) networking waveforms. Waveforms and enhancements are evaluated using a JTRS Surrogate Radio (JSR). We propose to modify a JSR through installation of radio security… more
Abstract:DESCRIPTION (provided by applicant): Anterior cruciate ligament (ACL) injuries are a significant problem for athletes, and women in particular. Both surgical and non-surgical treatment options exist, with the ultimate goal of regaining joint stability, knee kinematics, and quadriceps strength… more
Abstract:ABSTRACT: Availability of high quality, large area gallium nitride (GaN) single crystal substrates is one of the most outstanding issues for III-V nitride materials. Today's GaN device processes typically employ HVPE grown on sapphire and silicon carbide substrates, requiring elaborate buffer… more
Abstract:Solid State Scientific Corporation (SSSC) is pleased to propose the design of a single-board, integrated Hostile Fire Indication (HFI) system with the nominal size, weight, and power constraints for operation as an adjunct sensor within the AN/AVR-2B(V) Laser Warning Set. Work on Phase I will… more
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