Abstract:The United States and several other countries are investing in new neutron scattering facilities as well as upgrading existing ones due to their promise for fundamental and applied research that can catalyze advances in energy, telecommunications, manufacturing, plastics, transportation,… more
Abstract:DESCRIPTION (provided by applicant): New clinical guidelines for the treatment of exacerbations in cystic fibrosis (CF) were recently published by the American Thoracic Society. Examples of these evidence-based recommendations include not performing synergy testing to combat multi-drug-resistant… more
Abstract:DESCRIPTION (provided by applicant): Assessment of lung function in neonates and infants Lung disease is the most common chronic disease of childhood, but methods for assessing lung disease such as spirometry cannot be performed by young children. Thus clinicians have only parental reports of… more
Abstract:DESCRIPTION (provided by applicant): Roughly one million Americans with inadequately controlled severe persistent asthma have a particularly high risk of exacerbations, hospitalizations, and death, and account for a per-patient health care burden exceeding12,000 annually. Bronchial thermoplasty (BT)… more
Abstract:This Small Business Innovation Research Phase I project will investigate the development of performance bio-based latex from alkyl itaconates for application in wood coatings. Identified by DOE in 2004 as a top 12 renewable chemical, itaconic acid and its derivatives have potential use in polymers… more
Abstract:Datacenters house server farms that perform many different jobs ranging from search engines to supercomputing. In aggregate these computer systems already consume enormous power, and their energy requirements are increasing both in absolute terms and in proportion to the total capacity of the… more
Abstract:Coal-fired integrated gasification combined-cycle (IGCC) power plants need to be able to increase their power outputs during peak demand periods without increasing CO2 emissions to improve power grid quality and increase power grid security. We propose to develop a compact, low-cost… more
Abstract:Tantalum alloy and silicon nitride gun barrel liners have demonstrated excellent corrosion resistance and wear characteristics for U.S. Army applications. The quality and accuracy of the rifling profile is critical; however, the processes and tooling needed to successfully rifle a gun barrel made… more
Abstract:The objective of the Phase I project is to prove the feasibility of the Automated Naloxone Delivery System (ANDS) by: (1) designing the physiological monitoring and prediction algorithm used to trigger the injection; (2) designing and developing prototypesof the automated naloxone injection system;… more
Abstract:The objective of this proposal is to develop, implement and evaluate a set of accurate and robust algorithms specifically designed to capture and measure multilateral social interactions automatically through audio-based methods based on asymmetric data design. We propose to accomplish this by: 1)… more
Abstract:DESCRIPTION (provided by applicant): The immune system depends upon an exquisite balance between positive and negative signals to maintain proper function. However, disruptions of this balance can lead to inappropriate responses: for example loss of negative regulation can result in autoimmunity.… more
Abstract:This Small Business Innovation Research Phase I project will develop a silicon solar cell with unique junction design that provides synergistic benefits as the thickness of the solar cell is reduced. Thin silicon solar cells are currently the subject of intense interest because, in comparison to… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will demonstrate the technical and commercial viability of a high-brightness ultraviolet light-emitting diode (UVLED) system for inducing an involuntary avoidance response of birds and bats. The purpose of this system is to reduce the… more
Abstract:There is a need for developing a new generation of lightweight, rapidly deployable semi-permanent infrastructure to support the Armys transition to a Modular Force. Existing metal frame and airbeam designs, notwithstanding their many innovations, fail to take full advantage of the weight savings… more
Abstract:This technology introduces a new non-invasive, biopsy-adjunct with a MNP platform for targeted tumor delivery. It employs closely sized magnetic nanoparticles (CS-MNP's) for determining their concentration and spatial distribution in tumor vasculatures asmeasured by magnetic resonance imaging… more
Abstract:Spire Semiconductor proposes to make an InGaAs-based three-junction (3J) tandem thermophotovoltaic (TPV) cell to utilize more of the blackbody spectrum (from a GPHS) efficiently. Semi-insulating InP wafers will be used for monolithically integrated module (MIM)compatibility and to achieve low… more
Abstract:Photochromic technologies that can modulate absorption, emission and reflection properties show promise as a means to achieve visual signature reduction for vessel in an oceanic environment. Dynamically changing the vessel"s color, brightness, and hull coating patterns will minimize a… more
Abstract:NATL will perform additional extreme live fire schedules beyond the exploratory scope of Phase 1. NATL will push Dark Metal's capability to thermally manage abrasion and wear resistance demonstrated in Phase 1. NATL will further push previouse live fire round counts to the extreme to… more
Abstract:One of the foremost issues confronting our nation is that of energy security. Lessening our dependence on foreign fossil fuels necessitates progress and growth in the renewable energy sector. However, widespread adoption of clean energy currently faces the challenge of power consistency a dilemma… more
Abstract:Water quality remote sensing has grown to allow for operational monitoring of trophic status, assessment of cyanobacteria blooms, and historical and trend analysis of water quality. Now, with the exponential growth of mobile technologies new opportunities can remove barriers to operational products… more
Abstract:Agricultural row crops occupy hundreds of million acres of land in the United States. Decisions regarding the implementation of tillage practices in these agricultural areas have a significant effect on other environmental outcomes including soil erosion, water quality, and carbon sequestration. In… more
Abstract:Thermal batteries are a power source for most MDA weapons systems. Some of these systems have severe constraints on weight and size, and for this reason, advanced thermal batteries are needed that can provide greater power in smaller and lighter packages. The key components of conventional thermal… more
Abstract:This Phase 2 SBIR proposal addresses the technical and manufacturing challenges associated with development of cost-effective materials solutions for ultrahigh temperature solid rocket motor throat components V particularly those associated with boost nozzle solid rocket motor (SRM) or solid… more
Abstract:DESCRIPTION (provided by applicant): Systemic sclerosis (SSc) is an autoimmune disease that presents with a heterogeneous and complex phenotype. Major manifestations of the disease are skin fibrosis, vascular dysfunction, and immune system activation. There are no validated diagnostic markers. There… more
Abstract:DESCRIPTION (provided by applicant): Septic shock is a dire outcome of sepsis, an acute systemic inflammatory state triggered by an infection. In the USA, over 750,000 episodes of sepsis occur each year and mortality reaches 30%. The high prevalence of such devastating outcomes highlights the… more
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