Abstract:DESCRIPTION (provided by applicant): Triple-negative breast cancer (TNBC) is a subset of breast cancers with poor prognosis and high mortality due to the lack of effective therapeutic regimens. This Phase I SBIR application is to develop E1-Rap, a novel immunoRNases, for treating TNBC. E1-Rap is a… more
Abstract:DESCRIPTION (provided by applicant): The main goal of this Phase I/II SBIR application is to translate rapidly preclinical findings that show the advantage of using a combination radioimmunotherapy plus immunotherapy treatment regimen that uses non-competing antibodies for the improved treatment… more
Abstract:Many U.S. manufacturers need advanced simulation tools to maintain competitiveness in the world marketplace. The Department of Energy has developed several advanced simulation codes that could help, but the tools are too difficult for engineers in U.S. industry to use. VisIt is one such code that… more
Abstract:This SBIR Phase I proposal is aimed at the development of the ultra-sensitive detector for the far infrared (FIR) and terahertz (THz) bands of electromagnetic radiation. The device is inherently optical, operates at room temperature and of submillimeter size. The proposed technology is based on… more
Abstract:We propose to design and implement a system that combines multiple audio transcription and multiple translation tools with natural language processing capabilities, such that information can be automatically extracted from audio files with improved performances. In our approach, speech waveforms of… more
Abstract:DESCRIPTION (provided by applicant): Recent advances in photoacoustic tomography (PAT) have demonstrated its potential for 3D noninvasive high resolution imaging of soft tissues at penetration depths of many centimeters. Further, and perhaps even more importantly, imaging of tissue structure can be… more
Abstract:Linearizer Technology Inc. produces analog predistortion linearizers. Integrated with a power amplifier (PA) and used for SATCOM applications they approach the performance of an ideal amplifier. Limitations of LTI's linearizers are the need for meticulous tuning to achieve the desired… more
Abstract:In response to the DHP 12-010 self powered biosensor solicitation, MaXentric proposes the VitalH system. Acknowledging the difficultly in creating a completely self-powered bio-sensor system that wirelessly transmits vital sign information, MaXentric has developed a solution which is extremely power… more
Abstract:Space presents a challenging environment for computing. Extended development times and radiation tolerance requirements leave hardware performance a decade or more behind the terrestrial state-of-the-art at the time of deployment. Additionally, once deployed, hardware changes are impractical,… more
Abstract:In response to the SOCOM 13-004 Next Generation Portable Power Amplifier solicitation, MaXentric proposes the GreenAmp-lite system. The GreenAmp- & #8208;lite combines MaXentric"s envelope tracking technology with a power amplifier MMIC in a single small footprint package. This tight… more
Abstract:ABSTRACT: The significance of the 71-76 and 81-86GHz frequencies cannot be overstated. The 10 GHz of spectrum available represents by far the most ever allocated at any one time, representing 50-times the bandwidth of the entire cellular spectrum. With 5 GHz of bandwidth available per channel,… more
Abstract:ABSTRACT: As the size, cost, and power consumption of digital signal processing platforms continue to drop and their performance improves, incorporating digital beam-former (DBF) designs into future SATCOM satellite payloads has become an increasingly attractive option. The advantages offered by… more
Abstract:ABSTRACT: MaXentric"s proposed Digital Chaotic Waveform Study (DC-WavS) will determine an optimal chaotic spread spectrum waveform for utilization in secure communications over the target Air Force SATCOM environments. The focus will be on chaotic signal generation schemes that are based on… more
Abstract:The Ka-/Q-band satellite systems offer potential for transportable and mobile communications through the effective use of the wide bandwidths available while requiring that adequate linearity performance be maintained. In environments where size and power conservation is of high importance, power… more
Abstract:In this Program MaXentric is developing an innovative cost effective high performance circulators/isolators for Navy S-Band through X-Band shipboard radars and wide bandwidth electronic warfare (EW) systems. Our Phase II goals can be summed up into one ultimate goal, to have a final prototype ready… more
Abstract:ABSTRACT: As the size, cost, and power of digital signal processing platforms continue to drop and their performance improves, incorporating digital beamformer into future SATCOM satellite payloads has become an increasingly attractive option. This is particularly true as the number of active… more
Abstract:As new applications arise for small gas turbine engines, the need to advance engine component technologies becomes essential, since they are required to run faster, hotter, and longer. Particularly critical in this regard are the shaft bearings. Since they operate without lubricant, air foil… more
Abstract:ABSTRACT: Mechanical Solutions Inc. is developing a general rotating machinery predictive maintenance (PDM) system called Sentry. The goal of the effort is to deploy the system on various machinery trains throughout Arnold Air Force Base. The generalized architecture of the system will also make… more
Abstract:The Phase I project analytically demonstrated that significantly improved engine cooling fan performance levels can be achieved for Paladin Integrated Management (PIM) vehicle that uses the same engine as the Bradley Fighting Vehicle, and the heavy payload variant of the Joint Light Tactical Vehicle… more
Abstract:MSI successfully demonstrated modification of its existing extended range 40mm non-lethal munition to carry and deploy a molecularly imprinted polymer (MIP) payload intended to detect and confirm explosives at 100m stand-off. Based on analysis and air-gun testing, as well as legacy performance of… more
Abstract:We propose to advance the state-of-the-art of durable superhydrophobic coatings for application on printed circuit boards (PCBs) found on underwater vehicles exposed to hydrostatic pressures up to ~10 atm, corresponding to depths of ~100 meters in fresh or salt water, through a combination of… more
Abstract:ABSTRACT: We propose to demonstrate the benefits of a self-healing coating (SHC) system (comprised of MIL-PRF-85285 compliant self-healing top coat; MIL-PRF-23377 Class N primer; chromate-free pretreatment) on repaired and restored aluminum. Innovations are proposed for a self-healing… more
Abstract:ABSTRACT: Due to their high strength to weight ratio, fiber reinforced composites (FRCs) are attractive structural materials for Air Force applications. Multi-functional self-healing FRCs will be beneficial in applications that either currently use FRCs, or will use them in the future. The… more
Abstract:This proposed study intends to develop a model and prototype of a flapping winged vehicle through the incorporation of elastic components. This will allow the manufacture of such vehicles with greatly enhanced flight duration and agility. Work will include the design, prototyping, and testing of… more
Abstract:Minimization of blade tip clearance in the high pressure turbine and high pressure compressor is very important for turbine efficiency, reduction of emissions, and lower rotor inlet temperature which extends the service life of the engine. This can result in increased payload, extension of mission… more
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