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Displaying 3376 – 3400 of 3877 Awards
Company: Peak Instruments Inc. Agency/Program/Year/Phase: DOE / SBIR / 1991 / 2
Abstract: A NEW TYPE OF WAVELENGTH DISPERSIVE (WD) X-RAY SPECTROMETER IS PROPOSED. ITS ANTICIPATED ATTRIBUTES OF HIGH EFFICIENCY AND SMALL PHYSICAL SIZE MAKE IT SUITABLE FOR USE ON ANALYTICAL ELECTRON MICROSCOPES (AEMS), WHERE CURRENT WD SPECTROMETERS ARE GENERALLY INAPPROPRIATE. PRELIMINARY CALCULATIONS… more
Company: Per Ii Systems Inc. Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: N/A
Company: PRINCETON SCIENTIFIC INSTRUMENTS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: THIS PROJECT WILL INVESTIGATE THE ADVANTAGES OF A NEW 2,048 X 2,048-PIXEL CCD-TYPE SOLID-STATE IMAGE SENSOR FOR X-RAY DIFFRACTION APPLICATIONS ON BIOLOGICAL MACROMOLECULES. THE CCD WILL BE FIBEROPTICALLY COUPLED DIRECTLY TO AN X-RAY-SENSITIVE PHOSPHOR SCREEN, ELIMINATING THE IMAGE INTENSIFIER… more
Company: PRINCETON SCIENTIFIC INSTRUMENTS, INC. Agency/Program/Year/Phase: DOD / SBIR / 1991 / 2
Abstract: THIS IS A PROPOSAL TO DESIGN, MANUFACTURE AND DELIVER A NEW FULLY AUTOMATED INSTRUMENT TO MEASURE, RECORD AND ANALYZE THE OXYGEN EQUILIBRIUM CURVE OF BLOOD AND/OR HEMOGLOBIN SOLUTIONS. IT WILL BE A WORKING VERSION OF AN INSTRUMENT EXISTING IN THE CONTRACTING ARMY LABORATORY. IT WILL BE FULLY… more
Company: PRINCETON SCIENTIFIC INSTRUMENTS, INC. Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: A TANK CANNON GUN BARREL BENDS UNDER THE INFLUENCE OF TANK MOTION, SOLAR HEATING, AND DURING AND AFTER FIRING ROUNDS OF AMMUNITION. BY DETECTING THE RESULTANT ANGULAR MOTION OF THE MUZZLE RELATIVE TO THE TRUNNION IN REAL TIME THE FIRE CONTROL SYSTEM CAN CORRECT THESE SIGNIFICANT SOURCES OF POINTING… more
Company: PRINCETON SCIENTIFIC INSTRUMENTS, INC. Agency/Program/Year/Phase: NASA / SBIR / 1991 / 1
Abstract: IN MOST CURRENT XUV IMAGE SENSORS, THE PHOTOCATHODE IS EVAPORATED ON THE SURFACE OF A MICROCHANNEL PLATE. HOWEVER,THE DETECTIVE QUANTUM EFFICIENCY OF THESE DEVICES IS DEGRADED BY THE MICROCHANNEL PLATE SURFACE AND THE ATTENDANTPHOTOELECTRON BALLISTIC PATH IN REACHING THE CHANNELS. IN COMPARISON WITH… more
Company: PRINCETON SCIENTIFIC INSTRUMENTS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: N/A
Company: PRINCETON SCIENTIFIC INSTRUMENTS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: N/A
Company: Pxl, Inc.orporated Agency/Program/Year/Phase: NSF / SBIR / 1991 / 1
Abstract: THERE IS NEED FOR CONVENIENT, VERSATILE X-RAY SOURCES WHICH CAN BE PRECISELY CONTROLLED SPATIALLY AND TEMPORALLY. USED STROBOSCOPICALLY, SUCH DEVICES COULD REVOLUTIONIZE NON-DESTRUCTIVE TESTING AND BE UTILIZED WITH ADVANTAGE IN MORE CONVENTIONAL ROLES, INCLUDING MEDICAL DIAGNOSTICS AND HIGH… more
Company: Pxl, Inc.orporated Agency/Program/Year/Phase: NSF / SBIR / 1991 / 1
Abstract: THE WORLD IS THREE DIMENSIONAL (3D), BUT DATA DISPLAYS ARE ONLY TWO DIMENSIONAL (2D). PXL PROPOSES A NOVEL SOLUTION TO THIS PROBLEM. THE 3D DATA VOLUME IS SECTIONED INTO A NUMBER (20-100) OF 2D IMAGES. CONSECUTIVE 2D IMAGES ARE THEN DISPLAYED SEQUENTIALLY IN A CONTINUOUS LOOP. THE 3D VIEW IS… more
Company: Pxl, Inc.orporated Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: RECENT, REVOLUTIONARY PROGRESS IN X-RAY SOURCES AND OPTICS OPENS UP EXCITING POSSIBILITIES FOR ADVANCING X-RAY MICROSCOPY OF BIOLOGICAL SPECIMENS IN THEIR NATURAL STATE. SUBSTANTIAL EFFORTS ARE BEING MADE TO UTILIZE SYNCHROTRON RADIATION FOR THIS PURPOSE. HOWEVER, EXPOSURE TIMES ARE TOO LONG-CHANGES… more
Company: Pxl, Inc.orporated Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: ATOMIC FORCE MICROSCOPY (AFM) VIEWS NON-CONDUCTING SURFACES AT ATOMIC RESOLUTION BY MEASURING DEFLECTION OF A LEVER WITHAN ATOMICALLY SHARP TIP. THE SMALL FORCES (10(-13) TO 10(-8)NEWTONS), AND DEFLECTIONS (OF THE ORDER OF ANGSTROMS) ARE MEASURED USING A TUNNELING TIP. THE INTER-ATOMIC FORCES… more
Company: Pxl, Inc.orporated Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: THE DEVELOPMENT OF X-RAY OPTICS ALLOWING FOR THE PRESERVATION OF FLUX IN THE IMAGING SOFT X-RAY MICROSCOPE IS OF GREAT IMPORTANCE. PXL'S NOVEL DEVICE, THE SOFT X-RAY DIFFRACTION PLATE, SHOULD CONTRIBUTE TO THE INCREASE OF SOFT X-RAY FLUX THROUGH THE IMAGING SYSTEM BY AN ORDER OF MAGNITUDE. IT WILL… more
Company: Pxl, Inc.orporated Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: N/A
Company: Pxl, Inc.orporated Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: N/A
Company: Rhomed, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: A NEW METHOD OF DIRECT LABELING OF ANTIBODIES WITH TECHNETIUM-99M (TC-99M) WILL BE DEVELOPED AND EVALUATED. INTHIS METHOD, CALLED THE REGULATED REDUCTION METHOD, ONE CHEMICAL MEANS IS USED TO BREAK THE DISULFIDE BOND IN THE PROTEIN, AND A SEPARATE CHEMICAL MEANS IS USED TO REDUCE THE SODIUM… more
Company: Rhomed, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: THE OBJECTIVE OF THE STUDY IS TO DEVELOP A PAN-T-LYMPHOCYTE 99MTC-RADIOTRACER WHICH CAN BE USED TO STUDY TRAFFICKING OF STIMULATED LYMPHOCYTES AND AS A DIAGNOSTIC RADIOPHARMACEUTICAL FOR CHRONIC INFECTIONS SUCH AS OSTEOMYELITIS AND FOR GRANULOMATOUS DISEASES. THE PLANT-DERIVED ISOLECTIN,… more
Company: Sign Assessment, Inc Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: THE LONG-TERM GOAL OF THE PROJECT IS TO PRODUCE MARKETABLE, RESEARCH-BASED CHECKLIST FOR ASSESSING AND MONITORING THE SIGNED LANGUAGE DEVELOPMENT OF DEAF CHILDREN. TYPICALLY, CHILDREN WITH SUBSTANTIAL HEARING IMPAIRMENTS EXPERIENCE DELAYS IN ACQUIRING ENGLISH, BUT ACCESS TO A SIGNED LANGUAGE MAY… more
Company: Silhouette Technology, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: N/A
Company: Sonokinetics, Inc Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: IT IS POSTULATED THAT INTENSE (> 3 W/MM2) ACOUSTIC VIBRATION CAN BE CONVEYED WITH SUFFICIENT INTENSITY THROUGH A FLEXIBLE CONDUIT TO INTRAVASCULARLY EXCAVATE ATHEROSCLEROTIC PLAQUE. THE SYSTEM TO BE EVALUATED CONSISTS OF: (1) AN ACOUSTIC TRANSDUCTION CAVITY CONTAINING A MAGNETOSTRICTIVE PISTON… more
Company: Synaptic Pharmaceutical Corp. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: MOLECULAR CLONING AND HETEROLOGOUS EXPRESSION OF NEUROTRANSMITTER RECEPTOR GENES PROVIDE A MEANS TO STUDY THESE SITES OF DRUG ACTION FREE FROM THE COMPLEXITIES OF INTACT NEURAL TISSUE. THESE HETEROLOGOUS EXPRESSION SYSTEMSCAN THEN BE USED AS ASSAY SYSTEMS IN THE DEVELOPMENT OF NEW THERAPEUTIC AGENTS… more
Company: Synaptic Pharmaceutical Corp. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: THE SEROTONIN 5-HT1P RECEPTOR HAS BEEN EXTENSIVELY CHARACTERIZED IN THE ENTERIC NERVOUS SYSTEM WHERE IT FUNCTIONS IN THE REGULATION OF GASTROINTESTINAL MOTILITY. IN ADDITION, 5-HT1P-LIKE BINDING SITES HAVE BEEN DISCOVERED IN THE PERICARDIUM AND ENDOCARDIUM OF THE HEART, THE INNERVATION OF THE SKIN,… more
Company: Synaptic Pharmaceutical Corp. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: DOPAMINERGIC NEUROTRANSMISSION PLAYS A SIGNIFICANT ROLE IN PSYCHIATRIC AND EXTRAPYRAMIDAL DISORDERS, ENDOCRINE FUNCTION, AND VASODILATION. TO BETTER UNDERSTAND THE DOPAMINE D1 RECEPTOR AS A POTENTIAL SITE FOR DRUG DEVELOPMENT, IT IS PLANNED TO IDENTIFY AND CHARACTERIZE THE RECEPTOR GENE BY… more
Company: Synaptic Pharmaceutical Corp. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: OPIATE RECEPTORS, WHICH ARE IMPORTANT PHARMACOLOGICAL TARGETS FOR ANALGESIA AND FOR THE CONTROL OF DRUG ADDICTION,HAVE NOT BEEN CLONED AND THEIR AMINO ACID SEQUENCES ARE UNKNOWN. RECENT WORK INDICATES THAT SEVERAL OPIATE RECEPTORSUBTYPES ARE COUPLED TO G PROTEIN SECOND MESSENGER SYSTEMS. THEREFORE,… more
Company: Technical Imaging Services In Agency/Program/Year/Phase: DOD / SBIR / 1991 / 2
Abstract: OPTICAL ARCHITECTURES ARE NEEDED FOR REPRESENTING AND MANIPULATING THREE-DIMENSIONAL DATA OBJECTS IN A DATABASE ENVIRONMENT. A CLASS OF ARCHITECTURES BASED ON ARRAYS OF OPTICAL LOGIC DEVICES INTERCONNECTED IN FREE SPACE WILL BE STUDIED WITH THE EXPECTATION THAT THESE SYSTEMS WILL BE COMMERCIALLY… more
Displaying 3376 – 3400 of 3877 Awards
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