Abstract:A new, very inexpensive, lightweight (25 mg/cm^2), low power (micro-W/cm^2), electrochemical voltammetric sensor technology for CW agents, based on unique conducting polymer microporous membranes and ionic liquid electrolytes with very wide operating temperature, is offered. Voltammetric sensing… more
Abstract:DESCRIPTION (provided by applicant): Uncontrolled hyperbilirubinemia (jaundice) in neonates has long been known to lead to neurological dysfunction including irreversible athetoid cerebral palsy with speech, ocular and hearing impairments, and even death.Contemporary management is based upon… more
Abstract:DESCRIPTION (provided by applicant): The objective of the project is to demonstrate that it is feasible to fabricate a bioresorbable drug eluting poly (l-lactide) (PLLA) stent with appropriate mechanical properties using our newly developed novel rapid stent fabrication (RSF) system. This novel… more
Abstract:DESCRIPTION (provided by applicant): The proposed SBIR Phase II project aims at developing a new drug product, the naltrexone orally dissolving film (ODF), for treatment of alcohol dependence. The naltrexone ODF is a small, thin, and flexible film, containing naltrexone hydrochloride and other… more
Abstract:Purpose: In education research, the standardized mean difference (symbolized by d) is the predominant effect size index. It is calculated as the difference between the treatment-group and control-group means, divided by the pooled standard deviation. Using d allows the impacts of education… more
Abstract:The goal of the present proposal is to identify and demonstrate enhanced, efficient radar imaging and applications exploiting modern waveform generation. In addition, MIMO beam formation for robust compressive sensing in Maritime applications such as small craft detection and imaging is also… more
Abstract:DESCRIPTION (provided by applicant): A causative role of high-risk human papillomavirus (HPV) types in human cancer has been established, particularly for those of the anogenital region including cervical and anal cancers. The etiologic course of such cancers is thought to involve HPV infection,… more
Abstract:Both NASA and the FAA have identified large civil tiltrotors (LCTRs) as the most promising method for meeting FAA goals for extending future airport capacity, flexibility, efficiency and safety. This has led to important research at NASA exploring flight dynamics and handling qualities associated… more
Abstract:ABSTRACT: Noise alleviation for tactical jet aircraft is critical for community acceptance of military operations. While new fixed-geometry engine nozzles can mitigate noise, adaptive concepts can adjust to multiple flight conditions and reduce noise without compromising other performance metrics.… more
Abstract:Rugged tactical vehicles are critical to the success of U.S. Navy and Marine missions and must be transported around the globe at a moment"s notice. Many of these vehicles, such as the High Mobility Multipurpose Wheeled Vehicle (HMMWV), Interim Fast Attack Vehicle (IFAV) and Light Strike… more
Abstract:An advanced rotorcraft induced velocity software module has been developed for enhancing the fidelity of real-time piloted simulations of rotorcraft shipboard operations. This software module is built upon real-time solutions of the full-span, free-vortex rotor wake combined with fast panel models.… more
Abstract:Current comprehensive rotorcraft analyses typically use lifting line theories coupled with 2D look-up tables to determine rotor blade lift, drag and pitching moment. These methods cannot directly capture 3D flow effects that influence the aerodynamic characteristics of advanced planforms, complex… more
Abstract:Extensive work on developing new, high yield biologic sources of triglycerides continues around the world in an effort to diversify the worlds energy sources. Triglycerides, such as vegetable and algal oils, naturally consist of long hydrocarbon chains, making them excellent starting points for… more
Abstract:Topological data analysis is a new mathematical method used to study these massive data sets that arise in a variety of situations including military operations and national security. The use of passive infrared sensors for a wide area detection system involving chemical and biological contaminants… more
Abstract:The objective of this SBIR Phase II proposal is to develop and demonstrate an advanced lightweight EOD face shield system that fits on the lightweight ACH helmet and meeting ballistic, optical, functional and operational requirements for Advanced Bomb Suit. During Phase I effort, Frontier has… more
Abstract:The objective of this SBIR Phase II proposal is to demonstrate Frontier's innovative combustible materials for combustible small arms ammunition applications to achieve excellent burning efficiency with a very low burning residue, retain excellent structure integrity, accomplish more than 40%… more
Abstract:DESCRIPTION (provided by applicant): This project develops an automated protein preparation technology that uses magnetic microparticles to isolate histones in their native state from specific genomic loci of interest via the chromatin to which they are bound. After extraction, the targeted histones… more
Abstract:Breast cancer is a leading cause of malignancies in women, resulting in almost 200,000 new cases every year. In approximately one third of breast cancer patients, malignant cells spread to distant organs and cause metastatic tumors. Tumor progression, metastatic spread and patient prognosis depends… more
Abstract:DESCRIPTION (provided by applicant): For longitudinal field studies involving substance abusers, successfully tracking, locating, and following up with a representative sample of subjects is a challenge. One meta-analysis of 85 longitudinal studies of substance abuse clients found that nearly… more
Abstract:DESCRIPTION (provided by applicant): This Phase I application is being submitted with the main objective to develop a highly sensitive and specific imaging method for prostate cancer that is based on a bispecific antibody (bsMAb) pretargeting procedure. The key features of this imaging system is the… more
Abstract:DESCRIPTION (provided by applicant): The main objective of this Phase I SBIR application is to perform the first-in-man studies with a new antibody-drug conjugate (ADC) composed of a humanized antibody (hRS7) to the epithelial glycoprotein-1 antigen (EGP-1, also known as TROP-2) coupled to SN-38,… more
Abstract:The Department of Energy is seeking ancillary technologies to enhance the performance of high filed superconducting materials critical for the very high-field magnets to be used in a future particle accelerator. Bi-2212 round wire, a high temperature superconductor, is one of the best candidates for… more
Abstract:DESCRIPTION (provided by applicant): Dentin forms the bulk of the tooth and is covered by enamel in the crown of the tooth and cementum in the root. When dental caries breaks down enamel and involves the dentin, the patient experiences pain and thermal sensitivity. The acute phase of dental pulp… more
Abstract:DESCRIPTION (provided by applicant): This project consists of the research and development of a unique implantable ischemia monitor that uses subcutaneous sensors in the patient's torso to detect the onset of acute myocardial infarction (AMI). Upon detecting a heart attack, the monitor… more
Abstract:ABSTRACT: JMSI Inc (DBA Intelligent Light) proposes to develop EPISODE - a new large scale data management tool that enables an engineer to more readily extract knowledge and insight from their large scale physics based simulations and experimental data. The Extract Plug-In Scalable reduced Order… more
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