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Note: The Award Database is continually updated throughout the year. As a result, data for a given year is generally not complete until April of the following year.

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Displaying 5751 – 5775 of 6621 Awards
Company: Jupiter Technologies Inc Agency/Program/Year/Phase: NSF / SBIR / 1991 / 1
Abstract: FOR ELECTRONIC PACKAGING APPLICATIONS, THE THREE DESIRABLE PROPERTIES OF AN INSULATING CERAMIC SUBSTRATE ARE: HIGH THERMAL CONDUCTIVITY, THERMAL EXPANSION MATCH WITH THE DEVICE AND LOW DIELECTRIC CONSTANT. WHILE SOME MONOLITHIC CERAMICS SHOW PROMISE, AN ALTERNATIVE APPROACH IS TO DESIGN AND… more
Company: Ken Wanderman & Assoc Inc. Agency/Program/Year/Phase: NASA / SBIR / 1991 / 1
Abstract: N/A
Company: Knowledge Systems Concepts Inc Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: KSC IS A PRIVATELY OWNED RESEARCH AND DEVELOPMENT COMPANY THAT SPECIALIZES IN THE APPLICATION OF ADVANCED TECHNOLOGIES TO INFORMATION COLLECTION, ANALYSIS AND DISSEMINATION, AND TO THE DESIGN AND IMPLEMENTATION OF DECISION SUPPORT SYSTEMS. THE GOAL OF THIS PROJECT IS TO DEVELOP AN ADVANCED COMPUTER… more
Company: Knowledge Systems Concepts Inc Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: A BENCHMARK TOOL IS PROPOSED THAT MAKES POSSIBLEMEASUREMENT OF AN EXPERT SYSTEM TOOL'S PERFORMANCE CHARACTERISTICS WHEN APPLIED TO PROBLEMS OF ANY SPECIFIED SIZE AND COMPLEXITY. KEY CAPABILITIES FOR THE PROPOSED TOOL INCLUDE AN ARTIFICIAL KNOWLEDGE BASE GENERATOR, A KNOWLEDGE REPRESENTATION… more
Company: HYBRID TECHNOLOGIES Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: LEAD-SALTS HAVE BEEN THE ONLY SEMICONDUCTOR ALLOYS OF CAPABLE OF DIODE LASER EMISSION IN THE MID-INFRARED (3-30 UM). THESE DEVICES WERE HOMOSTRUCTURE DIFFUSED DIODE LASERS WHICH OPERATED CONTINUOUSLY ONLY AT CRYOGENIC TEMPERATURES. SUBSTANTIAL IMPROVEMENTS IN LEAD-SALT DIODE LASER PERFORMANCE HAVE… more
Company: HYBRID TECHNOLOGIES Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: OPTICALLY PUMPED KERR-LIQUID FILLED HOLLOW FIBER DEVICES ARE PROPOSED AS A NOVEL MULTIWAVELENGTH COHERENT LIGHT SOURCE WITH APPLICATIONS IN LIDAR AND COHERENT OPTICAL SENSOR SYSTEMS. THE DEVICES ARE BASED ON STIMULATED RAYLEIGH-KERR SCATTERING FROM A KERR-LIQUID-FILLED HOLLOW FIBER SYSTEM. THE… more
Company: HYBRID TECHNOLOGIES Agency/Program/Year/Phase: NASA / SBIR / 1991 / 1
Abstract: THE GOAL OF THIS PROJECT IS TO USE MOLECULAR BEAM EPITAXY (MBE) OF PBSNTE AND PBEUSETE ON PBTE SUBSTRATES TO DEVELOP AND FABRICATE BURIED HETEROSTRUCTURE (BH) TUNABLE SINGLE-MODE DIODE LASERS EMITTING IN THE 15MUM TO 28MUM SPECTRAL REGION WITH OPERATION TEMPERATURE IN EXECESS OF 20 K. THE BH DIODE… more
Company: LITRON LABORATORIES, LTD. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: MABS ARE HOMOGENEOUS PROTEINS THAT RECOGNIZE SPECIFIC EPITOPES ON AN ANTIGEN (E. G., A SOLUBLE PROTEIN OR A CELLULAR COMPONENT). BECAUSE OF THEIR SPECIFICITY, MABS CAN PROVIDE THE SCIENTIST WITH HIGHLY SELECTIVE REAGENTS THAT CAN BE USED FOR DIAGNOSTIC AND/OR THERAPEUTIC APPLICATIONS. AN ANTIBODY… more
Company: Medea Research Laboratoryto Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: THIS RESEARCH IS CONCERNED WITH ANTICYSTINOTIC AGENTS. CYSTINOSIS IS A FATAL METABOLIC DISORDER AFFLICTING 300 TO 400 CHILDREN NATIONWIDE. IT IS PRESENTLY CONTROLLED BY DAILY ADMINISTRATION OF CYSTEAMINE OR PHOSPHOCYSTEAMINE. THE REPULSIVE ODOR OF CYSTEAMINE BRINGS ABOUT AN OUTRIGHT REJECTION OF… more
Company: NANOPROBES, INC. Agency/Program/Year/Phase: DOE / SBIR / 1991 / 1
Abstract: A NEW GOLD PARTICLE HAS BEEN DEVELOPED THAT IS WATER SOLUBLE, CAN BE REACTED WITH NUCLEIC ACIDS IN A SPECIFIC WAY, AND IS HIGHLY SENSITIVE TO SILVER DEVELOPER. THIS SYSTEM HAS EXPERIMENTALLY DEMONSTRATED POTENTIAL TO DETECT 10(-20) MOL OF TARGET. IN PHASE I, BOTH THE COUPLING OF THEGOLD PARTICLE TO… more
Company: NANOPROBES, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: NEW METHODOLOGIES WILL BE USED FOR THE DETECTION AND QUANTITIZATION OF VERY SMALL AMOUNTS OF PROTEINS AND DNA SEQUENCES. A NEW GOLD PARTICLE WILL BE USED TO LABEL TARGET BIOMOLECULES, THEN STAINED WITH METALLIC SILVER BY EXPOSURE TO AQUEOUS SILVER (I) IONS AND A REDUCING AGENT. THE SILVER WILL THEN… more
Company: Neotronics Corp Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: THE HEAD PORTION OF THE PROPOSED ICE-MEASURING INSTRUMENT, WHEN SITTING ON THE ICE WILL DISPLAY A BRIM, ABOUT 7 INCHES ACROSS, WITH A SMALLER CONSOLE AT THE TOP, WILL HOLD FOUR TRANSDUCERS ARRANGED AT THE CORNERS OF A SQUARE, IN CONTACT WITH THE ICE SURFACE. THE CONSOLE WILL CONTAIN THE NECESSARY… more
Company: Niagara Systems And Software Agency/Program/Year/Phase: DOC / SBIR / 1991 / 1
Abstract: AN AFFORDABLE, RUGGEDIZED PERSONAL COMPUTER (PC) BASED SUBSYSTEM WHICH EXPERTLY VALIDATES, FILTERS, AND FUSES NAVIGATION DATA INPUTS FROM INDIVIDUAL SENSORS NOT ONLY WILLYIELD HIGHLY ACCURATE AND RELIABLE NAVIGATION VECTORS, BUT ALSO WILL PRESENT A COHERENT DISPLAY TO ASSIST SHIP'S BRIDGEOPERATIONS.… more
Company: Niagara Systems And Software Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: DEVELOPMENT OF AN AFFORDABLE, STANDARDIZED, LAPTOP/PORTABLE COMPUTER BASED HOME HEALTH CARE INTELLIGENT PORTABLE (HIP) WORKSTATION SYSTEM WILL OPTIMIZE DELIVERY OF HOME HEALTH CARE BY PROVIDING DIRECT COMMUNICATIONS AND PATIENT INFORMATION EXCHANGE AMONG HOME HEALTH CARE PROVIDERS IN NUMEROUS… more
Company: North East Semiconductor Inc Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: ALGAAS LASER DIODE ARRAYS USED AT 785-808 NM TO PUMP YAG-TYPE SOLID STATE LASERS NEED IMPROVEMENT IN RELIABILITY AND POWER EFFICIENCY. DIODE LASERS WITH INGAAS QUANTUM WELLS, USED FOR LONGER WAVELENGTH PUMPING, HAVE DEMONSTRATED IMPROVED LIFE AND EFFICIENCY. THIS PROGRAM WILL STUDY THE QUATERNARY… more
Company: Northeast Semiconductor Inc Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: A NEW PHOTODETECTOR FOR 10 UM WAVELENGTHS IS PROPOSED WHICH CONSISTS OF GAAS/ALGAAS QUANTUM WELLS INCORPORATED INTO A PNP ALGAAS PHOTOTRANSISTOR. BY APPROPRIATE ENGINEERING OF THE EPITAXIAL STRUCTURE, OPTICAL GAINS OF \100 SHOULD BE FEASIBLE IN THE PROPOSED DETECTOR. THE DEVICE SHOULD EXHIBIT… more
Company: Omnitek Research & Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: A MEDICAL WASTE PROCESSOR (MWP) IS PROPOSED TO SAFELY ELIMINATE MEDICAL WASTES GENERATED AT MILITARY AND CIVILIAN HEALTH FACILITIES. IT WILL BE DESIGNED TO OCCUPY MINIMUM SPACE, CONTROL SANITARY CONDITIONS, AND WILL PROVIDE A NONTOXIC RECYCLABLE BI-PRODUCT. THE MWP WILL SATISFY PRESENT AND PROJECTED… more
Company: Omnitek Research & Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: A PERSONAL COMPUTER-DRIVEN MATHEMATICAL MODEL IS PROPOSED TO ENABLE THE FORECASTING OF COST AND SCHEDULE EFFECTS FOR EACH CONTRACT CHANGE IMPOSED ON A SHIP CONTRUCTION CONTRACT. THE MODEL WILL ACCOMMODATE ANY TYPE CHANGE AND WILL INCLUDE THE RESOLUTION OF ADDITIONS, DELETIONS, MODIFICATIONS,… more
Company: Omnitek Research & Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: A MODIFIED COMMUNICATIONS SHELTER IS PROPOSED THAT WILL BE DIFFICULT TO DETECT BY STANDARD MEANS. IT WILL HAVE LOW RADAR CROSS SECTION (RCS), CONTROLLED INFRARED (IR) SIGNATURE, LOW VISIBILITY AND WILL MEET APPLICATIONS FOR ELECTROMAGNETIC SHEILDING. THE SHELTER WILL SATIFY STANDARD ENVIRONMENTAL… more
Company: ONCOGENE SCIENCE, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: TRANSFORMING GROWTH FACTORS TYPE BETA (TGF-BETA'S) ARE PROTEINS OF 25 KD DISULFIDE-LINKED HOMODIMERS AND HETERODIMERS THAT ACT TO CONTROL THE PROLIFERATION OF A VARIETY OF BOTH NORMAL AND TRANSFORMED CELL TYPES. IN ADDITION, TGF-BETA'S HAVE BEEN SHOWN TO STIMULATE WOUND HEALING AND TO ACT AS POTENT… more
Company: ONCOGENE SCIENCE, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: ACTIVATED RAS ONCOGENES HAVE BEEN IDENTIFIED IN A SIGNIFICANT PERCENTAGE OF CANCERS, INCLUDING LEUKEMIAS AND CARCINOMAS OF THE COLON, PANCREAS, AND LUNG. HIGH-AFFINITY ANTIBODIES REACTIVE WITH BOTH NORMAL AND ACTIVATED HUMAN P21RAS ARE AVAILABLE. HOWEVER, PREVIOUS ATTEMPTS TO DEVELOPANTIBODIES… more
Company: ONCOGENE SCIENCE, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: SPECIFIC PROTEIN- PROTEIN INTERACTIONS ARE CENTRAL TO MANY CELLULAR FUNCTIONS. DETECTION OF THESE INTERACTIONS HAS GENERALLY BEEN BY CO-IMMUNOPRECIPITATION ANALYSES. THESE METHODS HAVE DRAWBACKS DERIVING FROM THE NATURE OF THIS TECHNIQUE, INCLUDING THE DIFFICULTY OF CLONING GENE SEQUENCES FOR NEWLY… more
Company: ONCOGENE SCIENCE, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: ABNORMALITIES OF THE EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) APPEAR TO BE ASSOCIATED WITH A VARIETY OF PROLIFERATIVE DISEASES. IN HUMAN CARCINOMA BIOPSY SPECIMENS, OVEREXPRESSION OF EGFR IS FREQUENTLY OBSERVED TO OCCUR IN THE ABSENCE OF GENE AMPLIFICATION. IN PSORIATIC EPIDERMIS, AUTOCRINE… more
Company: ONCOGENE SCIENCE, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: SEVERAL CHROMOSOMAL TRANSLOCATIONS ASSOCIATED WITH DIFFERENT TYPES OF LEUKEMIAS HAVE BEEN RECENTLY CHARACTERIZED. AS A RESULT OF THESE TRANSLOCATIONS, NEW MRNA SPECIES ARE PRODUCED, CODING FOR NOVEL FUSION PROTEINS. THE GOAL OF PHASE I IS TO DEVELOP A PANEL OF NON-ISOTOPIC ASSAYS TO DETECT T(1;19)… more
Displaying 5751 – 5775 of 6621 Awards
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