Abstract:DESCRIPTION: Sirtuins and ADP ribosyltransferases (ARDTs) are two families of related enzymes that have important medically relevant functions. For example, SIRT3, a mitochondrial sirtuin, controls mitochondrial function, and thereby exerts a strong effect on metabolism, obesity, type 2 diabetes,… more
Abstract:DESCRIPTION (provided by applicant): NewPath Learning's Multimedia Lessons (MMLs) are complete, ready-to-use, interactive lessons for middle and high school students covering key life science topics. Each MML's self-contained curriculum content and software features provide engaging,… more
Abstract:DESCRIPTION (provided by applicant): Introduction: Ai Cure Technologies LLC was established in 2009 to develop automated medication adherence monitoring solutions using computer vision technology. This SBIR Phase II will allow Ai Cure Technologies to testthe accuracy and validity of its flagship… more
Abstract:Under this Small Business Innovation Research (SBIR) Phase II project, Automating Directly Observed Therapy as a Platform Technology, under Research Topic 139, the Contractor shall provide and evaluate the effectiveness and accuracy of a system for monitoring medication adherence in a treatment… more
Abstract:DESCRIPTION (provided by applicant): This grant application is by Ion Channel Innovations, LLC, (ICI) a company dedicated to the development of naked DNA transfer to treat the unmet needs of people with common smooth muscle diseases that negatively impactthe quality of life of millions. Overactive… more
Abstract:DESCRIPTION (provided by applicant): Diagnosis of active tuberculosis (TB) in TB-endemic countries, where gt90% of the global TB cases occur, depends upon microscopic examination of sputum smears made directly from the specimen. While this test is highly specific, the test is tedious, time-consuming… more
Abstract:The company intends the Ribbon Pump to be an economically sustainable technology; a version will be developed that can be manufactured, distributed and installed at a price and operating cost which is accessible to the most resource constrained farmers in less developed countries without subsidy.… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop a biologically inspired undulatory swimming device in which all motion is achieved by the cyclical elastic deformation of a pre-stressed form-finding structural system actuated by Electroactive Polymer (EAP) transducers. The… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project enables an innovative low cost approach to reaction bonded silicon carbide (RBSC). RBSC is a preferred material for mechanical seals, which are critical, costly components in many major manufacturing lines. The high cost of RBSC limits… more
Abstract:The requirement for cost effective manufacturing and metrology of large optical surfaces is instrumental for the success of future NASA programs such as LISA, WFIRST and IXO(now NGXO). OptiPro's UltraForm Finishing (UFF) is a sub-aperture compliant wheel and belt type polishing process for… more
Abstract:Future missile systems will abandon the traditional hemi-spherical shape for shapes resembling a tangent Ogive. An ogive shaped dome has better aerodynamic capabilities than its spherical counterpart. This enables the missile to fly faster, farther, and with more accuracy while also increasing its… more
Abstract:Conformal sensor windows have the capability of increasing the performance of an optical system while decreasing the aerodynamic drag. In many cases, these windows might conform to the platform they reside in. They may also be made out of optical materials that are resistant to the elements, thus… more
Abstract:Aerodynamically shapes missile domes have many benefits over traditional spherically shaped domes. To correct for optical aberrations presented by this non-traditional shape, free form corrective optics are required between the dome and the image sensor. For this example, the corrective optics shape… more
Abstract:Future missile systems will abandon the traditional hemi-spherical shape for shapes resembling a tangent Ogive. An ogive shaped dome has better aerodynamic capabilities than its spherical counterpart. This enables the missile to fly faster, farther, with more accuracy while also increasing its… more
Abstract:Nearly three billion people, half the worlds population, still cook on inefficient solid biomass fires, which emit gases and particulates that are both poisonous to humans and damaging to the environment. Four million deaths are attributed to indoor air pollution from biomass cooking fires every… more
Abstract:With rising energy costs and finite energy supply, Energy Conservation Measures are becoming increasingly important in the United States. This is particularly true in regard to buildings, which account for 40% of the total energy used in America. Currently, energy use in buildings can be assessed… more
Abstract:The benefits of using mobile devices for conducting business come with a range of security threats to sensitive information both in motion and at rest. To meet this need ATC-NY will develop Myelin, a cross-platform mobile app ecosystem with intrinsic security. Myelin uses a base technology of secure… more
Abstract:The protocols needed to coordinate the activities of distributed components, such as consensus algorithms, are notoriously difficult to design, implement, and verify. Abstraction is the only way to gain intellectual control over this complex problem; so ATC-NY and Cornell University have developed… more
Abstract:Cyber systems remain susceptible to attack and compromise despite the best security efforts. There are two growing trends in the research community to address this: a paradigm of prioritizing missions over individual network resources, and a push for resilient systems capable of fighting through… more
Abstract:If a computer system suffers a cyber attack, any compromised component that is simply reinstalled will remain vulnerable to the attack that damaged it; so replacements should provide equivalent services implemented differently. This defense can be applied proactively, to create a"moving… more
Abstract:ABSTRACT: The secure, automated dissemination of information across security domains requires accurate, complete, and standardized releasability markings. Existing sensors, information sources, and data processing tools do not all produce the required markings, nor can they always follow the… more
Abstract:Several mission-critical Navy applications are written as single-threaded Component Object Model) COM applications. They do not receive any benefits from the recent trend in computer architecture that emphasizes concurrent execution of multiple threads. ATC-NY will build Typhon, a plugin for Visual… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will design and build a technology platform that allows cloud infrastructures to run clients' tasks with full computation privacy. The cloud provider itself is unable to access to customers' workloads even in the presence of… more
Abstract:This Small Business Innovative Research Program Phase I project will develop a unique interactive online earth science educational tool that will meet current shortfalls in teaching earth sciences and related engineering technologies. This innovation will allow a learner to conduct realistic… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will develop integrated DC-DC power converters using magnetic thin-film power inductors. Currently, microprocessors and systems-on-chip (SoCs) are powered with board level voltage regulators assembled from discrete components. As supply… more
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