Abstract:Low cost and accurate monitoring of sequestered gases such as CO2 is critical to insure that sequestered gases are not reentering the atmosphere. Management requires, in part, improved atmospheric and ground monitoring of greenhouse gases through sensors capable of measuring the flux,… more
Abstract:Body armor used today is an achievement of modern science, constructed of high tensile strength, manmade fibers and ultra hard, impervious ceramics. As impressive as this armor is, however, one of the most critical areas of armor testing methodology has remained largely unchanged from its National… more
Abstract:ABSTRACT: The proposed solution would provide the United States Air Force (USAF) a thin client application for proactively identifying problem parts. Our solution is dependant on a digital Bill of Materials (BOM) which we also provide a tool for importing and loading the cleansed parts structure… more
Abstract:DESCRIPTION (provided by applicant): Diabetic retinopathy (DR) is a common complication of diabetes and a leading cause of vision loss in the United States. Unfortunately, there is no FDA-approved pharmacotherapy for DR. Current treatments in clinical practice and trails, such as laser… more
Abstract:DESCRIPTION (provided by applicant): Diabetes affects more than 8% of Americans and costs over 174 billion in 2007 in USA. Recently bariatric surgery, such as Roux-en-Y gastric bypass, has been proposed for treating diabetic patients with obesity due to its hypoglycemic effect on postprandial blood… more
Abstract:ABSTRACT: This program targets development of a high-performance thermoelectric (TE) cooler with a figure-of-merit, ZT>3, which greatly exceeds currently available technology. The cooler is fabricated using Group II-VI compound semiconductors, i.e. HgCdSe or HgCdTe, using a low dimensional… more
Abstract:This STTR Phase I proposal addresses a NASA need for improved near-to-mid IR detectors for imaging and spectroscopy. High performance IR detectors with cutoff wavelengths in the range of 2.5?5.0 microns will be developed using InGaAs / AlAsSb semiconductor materials. The proposal uses a two-pronged… more
Abstract:DESCRIPTION (provided by applicant): Early diagnosis of infectious disease is critical to patient outcome. An important early question is - is it a fungus, a bacterium or a virus? A rapid answer to this question would allow preemptive treatment that cansave lives. The goal of this project is a… more
Abstract:Cryptococcal meningitis (CM) kills more than 600,000 HIV-infected individuals globally per year, with the highest yearly incidence occurring in sub-Saharan Africa. There is a critical need for a simple diagnostic tool for cryptococcosis that can be used in resource-limited countries. An innovative… more
Abstract:DESCRIPTION (provided by applicant): Congestive heart failure (CHF) is one of the most serious medical challenges of our day. With 5 million Americans compromised by the ravages of this disabling disease, CHF is the leading cause of Medicare hospital admissions. The economic burden exceeds 40… more
Abstract:DESCRIPTION (provided by applicant): Pancreatic ductal adenocarcinoma (PDAC) is a solid tumor and is the fourth leading cause of cancer-related death in the U.S. The 5-year survival rate of its victims is lt5%. There is increasing evidence that most solidtumors have a subpopulation of… more
Abstract:ABSTRACT: Accurate prediction of part performance/reliability is at the core of health management of air vehicles and of supply chain management. Methodologies are needed to accurately predict/evaluate parts performance/reliability with compounding problem criteria/factors for early corrective… more
Abstract:This Small Business Technology Transfer Phase I project will create a fuel storage system for natural gas using adsorbent technology. This adsorbed natural gas (ANG) technology will allow this all-composite, conformable, lower pressure system to hold equivalent amounts of natural gas as… more
Abstract:DESCRIPTION: Incremental improvements in label free screening technologies over the past decade have not produced the capability necessary to support the changing needs of drug discovery programs. Persistent artifacts related to non-specific binding, promiscuous binding, precipitation, complex… more
Abstract:DESCRIPTION (provided by applicant): The Advanced Biofidelic Lower Extremity Kids prosthesis (ABLE Kids) project will advance the state-of-the-art of pediatric prosthesis systems by advancing the demonstrably successful Phase I device and refining it intoan ultracompact and lightweight form factor… more
Abstract:DESCRIPTION (provided by applicant): Stiffness and alignment of ankle-foot orthoses (AFOs) should be tuned optimally to maximize their function. Improperly tuned AFO may induce joint pain, reduced ambulatory function, and increased medical complications for patients with stroke. Therefore, the… more
Abstract:ABSTRACT: The engineer will be guided through the creation of criteria, alternatives and evaluation techniques in order to make a better decision. BENEFIT: The engineer will be guided through the creation of criteria, alternatives and evaluation techniques in order to make a better decision.
Abstract:ABSTRACT: As we move from a paper-based world into a digital environment, the internet will soon evolve from a virtual documentation system into a vibrant ecosystem of data where documents and human actors play an even smaller role. We are currently reaching a tipping point in history concerning… more
Abstract:This Small Business Innovation research Phase I proposes the development of a practical and reliable in-vitro test for detecting the evidence of Mycobacterium tuberculosis (MTB) infection as an alternative to the tuberculin skin test (PPD-TST) and to the interferon gamma release assays (IGRAs). The… more
Abstract:DESCRIPTION (provided by applicant): Diabetic retinopathy (DR) is a common complication of diabetes and a leading cause of blindness. This sight-threatening condition has become a public health challenge in the US. Currently, there is no FDA- approved drugfor DR. Laser photocoagulation has remained… more
Abstract:DESCRIPTION (provided by applicant): In spite of billions of dollars spent in the War on Cancer, cancer-specific mortality has changed little as a result, and the vast majority of cures are produced surgically, not from chemotherapy. The main problem is that even with early detection; most cancers… more
Abstract:DESCRIPTION (provided by applicant): Selexys Pharmaceuticals is developing a humanized monoclonal antibody drug called SelG1 directed against P-selectin for the treatment of vasoocclusive crisis in patients with sickle cell disease. The ultimate goal of this Phase IIB proposal is to further advance… more
Abstract:A collaboration between Amethyst Research Inc., University Multispectral Laboratories (a government-owned, contractor-operated nonprofit corporation), and Teledyne Imaging Systems (a large defense contractor) proposes to develop/improve high-performance infrared sensors based on Type II,… more
Abstract:In Phase I we demonstrated a novel in-situ cleaning technique based on UV-activated surface reactions involving ozone and hydrogen to remove organic adsorbates and chemically-bonded impurities, e.g oxides, from the substrate surface. In Phase II the program will develop this process to… more
Abstract:Improved performance SWIR sensors with extended wavelength response to 2.5 microns will be developed using two disruptive technologies with which Amethyst has demonstrated success: nBn detector structures and defect passivation via hydrogenation. Similar to conventional extended wavelength… more
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