Abstract:DESCRIPTION (provided by applicant): The primary objective of this proposal is to develop and commercialize a safe and more effective therapy for the treatment of Crohn's Disease, an inflammatory bowel disease. Crohn's Disease is a chronic inflammatory dis
order of the gastrointestinal tract that… more
Abstract:The InAs/InGaSb Strained Layer Superlattice (SLS) system is developing rapidly and is now finally poised to seriously challenge HgCdTe as the dominant technology for mid- and long-wave detection. SLS structures have a number of practical and theoretical advantages over HgCdTe materials, including… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop device structures for infrared sensor applications using lead chalcogenides. This system has reduced cooling requirements over other high performance infrared materials (such as HgCdTe) resulting from their reduced Auger… more
Abstract:3-C Cattle Feeder, in collaboration with the New Product Development Center [NPDC] at OSU will develop enhanced prototypes to be tested in the field. The doors to the feeder will be controlled by an RFID reader which actuates a motor allowing the feeder doors to open. For safety, the doors are… more
Abstract:As the Air Force (AF) begins the progression of applying systems engineering from the top-level definition of the system architecture down to a granular level of design it is very important to also realize the changes that will be taking place through Technology Insertion initiatives. Continuous… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Technology Transfer (STTR) Phase I project proposes to research and develop technology for the manufacture of a self-regenerating catalyst with an increased efficacy over commercial… more
Abstract:This Phase I SBIR research addresses two important and related needs regarding management of the national herd during an animal disease outbreak. First, is the need to facilitate keeping the national animal tracking databases (ATDs) as complete, accurate, and up-to-date as possible. The second is… more
Abstract:DESCRIPTION (provided by applicant): Diabetic retinopathy is a common complication of diabetes mellitus and a leading cause of severe vision loss and blindness around the world. The current interventions for DR, laser photocoagulation and vitrectomy, imped
e visual loss but do not improve vision for… more
Abstract:DESCRIPTION (provided by applicant): The objective of this proposal is to examine the efficacy of CLT-005 in reducing ocular inflammation and that occurs during endophthalmitis. Endophthalmitis occurs following the introduction of foreign pathogens into th
e eye. In addition to pathogenic virulence,… more
Abstract:Design Intelligence Incorporated, LLC (DII) proposes an integrated design approach for an innovative perching micro air vehicle (MAV) using energy harvesting. The proposed design concepts will build upon DIIs proprietary energy harvesting technology and hardware and will include innovative… more
Abstract:This SBIR Phase I research proposal will develop intelligent sensors for structural state sensing. It will demonstrate the feasibility of a successful intelligent structural state sensor concept. The advantage of this approach is that, unlike traditional sensors, this technology does not require… more
Abstract:In this Phase I SBIR program, RK Composites, Inc. (RKCI) will develop condition-based self healing systems for multifunctional composite materials. Our technology enables damage mitigation by pre-damage repair, inclusion of condition based monitoring, extensive and tailorable multifunctionality, and… more
Abstract:DESCRIPTION (provided by applicant): Bladder cancer kills approximately 13,000 Americans per year. At least half of these deaths are preventable with no improvements in screening because they occur in people who were initially diagnosed with superficial bl
adder cancer. The problem is that bladder… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Innovation Research Phase I research project seeks to develop a new technique for enhancing fluorescence-based detection of explosives in order to help counter the threat posed by… more
Abstract:DESCRIPTION (provided by applicant): Selexys Pharmaceuticals is developing a humanized monoclonal antibody drug directed against P-selectin for the treatment of vasoocclusive crisis in patients with sickle cell disease. P-selectin mediates the first step i
n the recruitment of white blood cells to… more
Abstract:DESCRIPTION (provided by applicant): Gastroparesis is a common disease defined as delayed emptying of the stomach. It is present in at least 20% of about 150 million patients with diabetes worldwide and in more than 20% of patients with functional dyspeps
ia that affects about 10%-25% of the… more
Abstract:This Navy SBIR Phase II program looks at the updating (both structural and electronics) of the current Controlled Towed Vehicle (CTV) and the fabrication of a new mount/enclosure that will allow for the mounting of the CTV system on a standard military style wing plyon. The vehicle is primarily for… more
Abstract:Yields and operability of high performance infrared focal plane arrays (IRFPAs), particularly those fabricated in HgCdTe, are severely impacted by material defects introduced during growth and/or processing. Amethyst Wafer Mapping (AWM) is a materials characterization technology which when fully… more
Abstract:Type II strained layer superlattice (SLS) p-n diode arrays fabricated on domestic-source GaSb substrates are a promising route to meet the critical need within DoD for large area, large format array infrared detectors. However, current SLS material quality is limiting detector performance. A… more
Abstract:While the initial application will be for cattle, the systems developed in this project will be applicable to feeders used for other domestic species including sheep, goats, and domestic hogs. In addition, the systems developed could be used to control gates or other access for animals or objects… more
Abstract:The Anautics CourseBook Project will address three national critical issues in mathematics education the need to support standards based instruction, the need to raise student achievement scores through effective teaching, the need for instruction management through electronic curriculum guidance,… more
Abstract:The Global War on Terrorism is increasing pressure for DOD depots to expedite the return of serviceable weapon systems to the warfighter while maintaining or decreasing maintenance costs. Each military service has responded to this challenge by undertaking enterprise-wide logistics modernization… more
Abstract:Many Department of Defense (DoD) weapon systems are operating beyond their original design specifications, resulting in failures requiring unplanned parts, materials and sustainment procedures. Such U.S. Air Force weapon systems are collectively denoted as aging aircraft. A large number of aging… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will examine the feasibility of a novel synthesis process for the creation of a composite hydrophobic nano-photocatalyst. The innovation is expected to allow enhanced volatile organic chemicals (VOC) and organic pollutant adsorptions in… more
Abstract:DESCRIPTION (provided by applicant): Linomide is a known anti-inflammatory drug. Recently we have synthesized a new analog of Linomide, linomide-5. The objective of this proposal is to develop linomide-5 as a therapeutic for treating diabetic retinopathy (
DR) and age-related macular degeneration… more
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