Abstract:The Anautics CourseBook Project will address three national critical issues in mathematics education the need to support standards based instruction, the need to raise student achievement scores through effective teaching, the need for instruction management through electronic curriculum guidance,… more
Abstract:The Global War on Terrorism is increasing pressure for DOD depots to expedite the return of serviceable weapon systems to the warfighter while maintaining or decreasing maintenance costs. Each military service has responded to this challenge by undertaking enterprise-wide logistics modernization… more
Abstract:Many Department of Defense (DoD) weapon systems are operating beyond their original design specifications, resulting in failures requiring unplanned parts, materials and sustainment procedures. Such U.S. Air Force weapon systems are collectively denoted as aging aircraft. A large number of aging… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will examine the feasibility of a novel synthesis process for the creation of a composite hydrophobic nano-photocatalyst. The innovation is expected to allow enhanced volatile organic chemicals (VOC) and organic pollutant adsorptions in… more
Abstract:DESCRIPTION (provided by applicant): Linomide is a known anti-inflammatory drug. Recently we have synthesized a new analog of Linomide, linomide-5. The objective of this proposal is to develop linomide-5 as a therapeutic for treating diabetic retinopathy (
DR) and age-related macular degeneration… more
Abstract:DESCRIPTION (provided by applicant): The objective of this proposal is to develop a service for the high-throughput drug screening of compounds to treat Age-Related Macular Degeneration (AMD). In our preliminary studies, we have identified a genetically-mo
dified mouse (Vldlr-/-) that presents with… more
Abstract:DESCRIPTION (provided by applicant): The objective of this proposal is to examine the efficacy of CLT-005, a novel small molecule inhibitor of Stat3, for treating inflammatory and vascular leakage of the retina of diabetic retinopathy. Retinal blood vesse
l formation is known to be mediated by the… more
Abstract:Technological advances in energy harvesting (EH) offer significant benefits to powering micro aerial vehicles (MAVs) by extending mission length and range. Currently, batteries limit the range and mission time of MAVs since the batteries contain a finite supply of energy. The proposed research is… more
Abstract:DESCRIPTION (provided by applicant): Most cancer deaths occur from metastatic tumors rather than from the primary tumor alone. Although many of the new drugs in the past decade are directed against tumors , changes in overall cancer survival have only been
modest. Most cures of cancer are still… more
Abstract:DESCRIPTION (provided by applicant): Accurately estimating individualized probability of developing breast cancer over time is clinically useful for early detection and prevention. InterGenetics Incorporated has developed OncoVue(R), a model incorporating
multiple, commonly occurring genetic… more
Abstract:DESCRIPTION (provided by applicant): The goal of this project is to develop a large-scale genotyping tool for metabolic muscle disease that can be applied to certain high risk groups in order to prevent life-threatening symptoms that are fast becoming a
public health problem. The triggering of… more
Abstract:Todays world and political climate lends itself to potential attacks by hostile forces and terrorists where both exterior and interior surfaces of vehicles, buildings, or equipment could become contaminated with biological warfare (BW) or chemical warfare (CW) agents. RTA Systems, Inc., proposes a… more
Abstract:The capture and use of carbon dioxide (CO2) from industrial plants for use in CO2 flooding of marginal oil reservoirs provides a dual use opportunity prior to final CO2 sequestration in the depleted reservoir. Miscible CO2 flooding processes greatly increase the recovery of crude oil from a… more
Abstract:DESCRIPTION (provided by applicant): The development of safe and effective female oral contraceptives (OCs) in the early 1960s provided a superior means of contraception and forever changed the dynamics of family planning. In fact, 82% of all women in the
U.S. have used OCs, which are one of the… more
Abstract:The Green Team, Inc. (tGT) will conduct Phase I research to determine characteristics of green product-service systems (GPSS) in the building products industry that effectively improve human health and the environment (e.g., improve sustainability). Knowledge of effective GPSS characteristics will… more
Abstract:DESCRIPTION (provided by applicant): Cancer is a group of diseases characterized by uncontrolled growth and spread of abnormal cells. Over one million people get cancer each year. Approximately one out of every two American men and one out of every three A
merican women will have some type of cancer… more
Abstract:ZAI proposes to investigate advancing the capabilities of our Smart Towed Vehicle to be mounted and operated onto a more diverse range of aircraft and applications. Currently the STV has been fully tested and operated on a Twin Otter. During Phase I ZAI will look at mounted options for other… more
Abstract:High-performance infrared detectors are mission-critical components of each layer of the Ballistic Missile Defense System. MDA is investing heavily in technologies that enhance producibility/operability of LWIR/VLWIR infrared focal plane arrays (FPAs), and reduce BMDS life cycle costs. HgCdTe is… more
Abstract:The yield and operability of high performance infrared detectors, particularly those based on HgCdTe, are severely compromised by materials defects. Recently, ARI has demonstrated during its UV hydrogenation process that deuterium effectively 'decorates' defects in materials such as ZnCdTe and… more
Abstract:This SBIR Phase I research project is to improve the performance of CdZnTe based gamma ray detectors by passivating as grown defects through a hydrogenization process. These defects are a source of leakage current and contribute to the backgound noise of the detectors. Successful completion of… more
Abstract:In order to monitor the location of sequested CO2 that has been injected in reservoirs, the most promising technology involves the use of geophones within wellbores. These geophones perform Vertical Seismic Profiling (VSP) and passive seismic monitoring. However, this geophone technology is… more
Abstract:The objective of this proposal is to identify and integrate multi-echelon constraints in Manufacturing Repair Overhaul (MRO) process planning and scheduling. The OC-ALC depot operates in a multi-echelon MRO environment that is highly constrained regarding its capacities, resources, deadlines, and… more
Abstract:The main goal of this work is to develop a more reliable, robust, and accurate measurements of radome transmission properties. As a result, we propose a pilot study in order to design a two-horn testing system and provide several prototype radome testing measurements. The proposed two-horn testing… more
Abstract:Due to the significant decrease of aircraft parts across the U.S. military over past years, managing parts more efficiently has become a great necessity. The term managing suggests having the data resources available to predict, forecast events or determine an item's use such as the mission… more
Abstract:Fine-scale, well-calibrated probabilistic weather forecasts are increasingly in demand for such weather-critical applications as battlespace management, and accurate prediction of high-value airborne operations. Built upon the Phase I effort we have just completed, the principal objective of this… more
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