Abstract:DESCRIPTION (provided by applicant): Clinical dilemma: Recent advances in biologic therapies for rheumatic diseases provide a means for more profound disease management. Proper diagnosis is a necessary aspect of choosing the proper biologic therapy. While
disease diagnosis, based on clinical… more
Abstract:Todays world and political climate lends itself to potential attacks by hostile forces and terrorists where both exterior and interior surfaces of vehicles, buildings, or equipment could become contaminated with biological warfare (BW) or chemical warfare (CW) agents. RTA Systems, Inc., proposes a… more
Abstract:The capture and use of carbon dioxide (CO2) from industrial plants for use in CO2 flooding of marginal oil reservoirs provides a dual use opportunity prior to final CO2 sequestration in the depleted reservoir. Miscible CO2 flooding processes greatly increase the recovery of crude oil from a… more
Abstract:DESCRIPTION (provided by applicant): The development of safe and effective female oral contraceptives (OCs) in the early 1960s provided a superior means of contraception and forever changed the dynamics of family planning. In fact, 82% of all women in the
U.S. have used OCs, which are one of the… more
Abstract:The Green Team, Inc. (tGT) will conduct Phase I research to determine characteristics of green product-service systems (GPSS) in the building products industry that effectively improve human health and the environment (e.g., improve sustainability). Knowledge of effective GPSS characteristics will… more
Abstract:DESCRIPTION (provided by applicant): Cancer is a group of diseases characterized by uncontrolled growth and spread of abnormal cells. Over one million people get cancer each year. Approximately one out of every two American men and one out of every three A
merican women will have some type of cancer… more
Abstract:ZAI proposes to investigate advancing the capabilities of our Smart Towed Vehicle to be mounted and operated onto a more diverse range of aircraft and applications. Currently the STV has been fully tested and operated on a Twin Otter. During Phase I ZAI will look at mounted options for other… more
Abstract:High-performance infrared detectors are mission-critical components of each layer of the Ballistic Missile Defense System. MDA is investing heavily in technologies that enhance producibility/operability of LWIR/VLWIR infrared focal plane arrays (FPAs), and reduce BMDS life cycle costs. HgCdTe is… more
Abstract:The yield and operability of high performance infrared detectors, particularly those based on HgCdTe, are severely compromised by materials defects. Recently, ARI has demonstrated during its UV hydrogenation process that deuterium effectively 'decorates' defects in materials such as ZnCdTe and… more
Abstract:This SBIR Phase I research project is to improve the performance of CdZnTe based gamma ray detectors by passivating as grown defects through a hydrogenization process. These defects are a source of leakage current and contribute to the backgound noise of the detectors. Successful completion of… more
Abstract:In order to monitor the location of sequested CO2 that has been injected in reservoirs, the most promising technology involves the use of geophones within wellbores. These geophones perform Vertical Seismic Profiling (VSP) and passive seismic monitoring. However, this geophone technology is… more
Abstract:The objective of this proposal is to identify and integrate multi-echelon constraints in Manufacturing Repair Overhaul (MRO) process planning and scheduling. The OC-ALC depot operates in a multi-echelon MRO environment that is highly constrained regarding its capacities, resources, deadlines, and… more
Abstract:The main goal of this work is to develop a more reliable, robust, and accurate measurements of radome transmission properties. As a result, we propose a pilot study in order to design a two-horn testing system and provide several prototype radome testing measurements. The proposed two-horn testing… more
Abstract:Due to the significant decrease of aircraft parts across the U.S. military over past years, managing parts more efficiently has become a great necessity. The term managing suggests having the data resources available to predict, forecast events or determine an item's use such as the mission… more
Abstract:Fine-scale, well-calibrated probabilistic weather forecasts are increasingly in demand for such weather-critical applications as battlespace management, and accurate prediction of high-value airborne operations. Built upon the Phase I effort we have just completed, the principal objective of this… more
Abstract:Information is one of the key warfighting resources of the 21st century as evidenced by the emphasis placed on ubiquitous communication strategies such as the Global Information Grid (GIG) initiated in 2004. However, the equipment, applications and networks comprising the Department of Defense's… more
Abstract:Brushfire proposes to adapt our revolutionary FireBreak architecture to include Network Probe capabilities to assist Army network operations personnel who must detect, trouble-shoot, and resolve network issues. These capabilities defined in the Phase I research project will enhance all network… more
Abstract:DESCRIPTION (provided by applicant): Diabetic retinopathy (DR) is a common complication of diabetes mellitus and a leading cause of blindness in developed countries. Abnormal angiogenesis in the retina or retinal neovascularization (NV) is one of the major
pathological changes in DR. Retinal NV can… more
Abstract:DESCRIPTION (provided by applicant): Diabetic retinopathy (DR) is a common complication of diabetes and a leading cause of blindness in the world. Diabetic macular edema (DME) and retinal neovascularization (NV) are the two major pathological alternatio
ns leading to vision loss in patients with… more
Abstract:DESCRIPTION (provided by applicant): Retinal vascular leakage or breakdown of the blood-retina barrier (BRB) is an early feature of diabetic retinopathy (DR) and can lead to diabetic macular edema (DME), which is the single greatest cause of vision loss in
diabetic patients. Currently, there is no… more
Abstract:Technological advances in energy harvesting (EH) offer significant benefits to powering micro aerial vehicles (MAVs) by extending mission length and range. Currently, batteries limit the range and mission time of MAVs since the batteries contain a finite supply of energy. The proposed research is… more
Abstract:Transmissible spongiform encephalopathies (TSE's), or prion diseases, are caused by a unique transmissible agent hypothesized to be a misfolded form (PrPD) of a normal host protein (PrPC). We will use chronic wasting disease (CWD) as a model prion agent because of growing concern about this agent,… more
Abstract:"The National Research Council has concluded that ammonia is a major concern for
air quality at global, national and regional scales. In the US, livestock operations are
believed to contribute over 80% of the total emissions of ammonia. Specific interest in
ammonia emissions from livestock… more
Abstract:"This project will test the feasibility of a breath alkane as an indicator of respiratory health in
bovine. Significant losses due to bovine respiratory disease (BRD) occur in the U.S. beef
industry with estimated annual losses at $1 billion due to higher medical costs, decreased weight
gain, lower… more
Abstract:Passage in 1996 of the Food Quality Protection Act (FQPA) and Amendments to the Safe Drinking Water Act (SDW) reflected these concerns and required EPA to develop a screening program, using appropriate validation test systems and other scientifically relevant information, to determine whether… more
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