Abstract:The goal of this work is the development of technology for detecting trace levels of explosives as an aid to force protection and for acquisition of forensic evidence. In Phase I of this effort we demonstrated that personnel involved in the manufacture, storage, deployment, and triggering of… more
Abstract:The goal of the project was to find a more efficient treatment for cancer while reducing the risk of radiation damage. To reach this goal, we propose a novel method for ovarian cancer treatment that combines radiotherapy and photodynamic therapy (PDT). Under this concept, luminescent nanoparticles… more
Abstract:Surface water quality impacts associated with intensive, largescale poultry production are significant and pervasive in many parts of the country. Production Specialities, Inc. (PSI) has developed process technology for converting waste (poultry litter and manure) into commercial eneefty and… more
Abstract:DESCRIPTION (provided by applicant): Obesity is a serious medical problem: in the United States alone, it causes approximately 300,000 deaths and estimated healthcare costs in the amount of $100 billion per year. However, currently available therapy remains unsatisfactory. In this project, we… more
Abstract:The short read range of current cattle electronic identification ear tags threatens to hinder the widespread adoption and utility of the USDA-developed National Animal Identification System (NAIS). Tag readers that require placement within inches of an animal's ear in order to read the NAIS number… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop a new passivation technique, derived from a recent discovery that semiconductors can be readily hydrogenated by simultaneous exposure to hydrogen gas and ultra-violet light. The technique has a number of advantages over… more
Abstract:75239S Municipal solid waste landfills are the single largest source of anthropogenic methane emissions in the United States, producing 7 million tons, or 34% of the nation's total methane pollution. According to the Intergovernmental Panel on Climate Control¿s third assessment report, methane… more
Abstract:Anautics proposes to discover, research, and evaluate new technologies, methods and tools, as well as recommend demonstrated capabilities known to them through working with Industry, Universities, Aging Aircraft, CASI and COSSI projects. While many systems promise to integrate all aspects of your… more
Abstract:The proposed system shall have the ability to learn from past actions and recommend best course of action for a maintainer. The proposed research is expected to benefit managers, equipment specialists, engineers, planners, schedulers, supervisors, and mechanics. Cost and flow day reduction… more
Abstract:DESCRIPTION (provided by applicant): The goal of the Small Business Innovative Research Phase II is to develop an Internet-based Caregiver Support System (ICSS) that enables care to be provided to persons with Alzheimer's over the Internet. The objectives of the system are to improve the quality of… more
Abstract:DESCRIPTION (provided by applicant): Diabetic retinopathy is a common complication of diabetes mellitus and a leading cause of blindness in the developed countries. There are two major pathological changes which impair vision in diabetic retinopathy: diabetic macular edema (DME) resulting from… more
Abstract:DESCRIPTION (provided by applicant): Diabetic retinopathy is a common complication of diabetes and a leading cause of blindness in the US and the world. Diabetic macular edema (DME) and retinal neovascularization are the two major pathological alternations leading to the vision loss in diabetic… more
Abstract:DESCRIPTION (provided by applicant): Diabetic retinopathy is a common complication of diabetes. It affects millions people and is a leading cause of blindness in the industrialized countries. In diabetic retinopathy, there are two major pathological changes responsible for vision loss, diabetic… more
Abstract:Aircraft maintenance, repair, and overhaul (MRO) organizations face the challenging task of scheduling maintenance work without knowing the full extent of the work content at the time of initial inspection. During the overhaul, new work is discovered requiring rapid re-sequencing of tasks and the… more
Abstract:Bovine Respiratory Disease is the most common illness among cattle arriving at feedlots and results in decreased weight gain, lower quality meat and death. BRD is highly transmittable and costs cattlemen more than all other diseases combined. A rapid and sensitive diagnostic method for BRD is not… more
Abstract:Attacks using chemical warfare (CW) agents are a principal threat to the US homeland and deployed assets. This proposal focuses on demonstrating key capabilities required to develop a micro-gas analysis (MGA) system that provides orders of magnitude improvement in sensitivity and a very high degree… more
Abstract:This Small Business Innovative Research (SBIR) Phase II project is to develop a novel material to enable improved performance of surface enhanced Raman spectroscopy (SERS). Availability of this material could result in the manufacture of pollution monitoring, industrial process monitoring, and… more
Abstract:In Phase I, Nomadics demonstrated that a novel chemical weapon indicating chromophore (CWIC) developed by Professor Tim Swager at MIT will allow equipment to be quickly and easily examined to show any areas of contamination, making targeted decontamination manageable. When exposed to CW agent… more
Abstract:Modern flight line engineers are faced with a large variety of sensor configurations. Different types of vehicles, and sometimes even different individual vehicles of the same type, have widely varying sensor loadouts. With current Instrumentation Support Systems (ISSs), each sensor configuration… more
Abstract:Current antibody-or enzyme-based chemical and biological sensors generally suffer from several disadvantages including involved development cycles, short shelf life, implementation difficulties, and no clear path for new receptor development. We propose an approach based on the use of… more
Abstract:The US military has a developed and is testing several technologies that promise to reduce fratricide incidents on the battlefield. These Radio-Based Combat Identification Systems consist of specially modified, currently inventoried, military radio systems. These systems do not allow… more
Abstract:This Small Business Innovative Research (SBIR) Phase II project will develop and introduce new low-dielectric constant polymers as a new dielectric material for the fabrication of interconnect systems in integrated circuits. The continuing drive for denser integrated circuits and faster… more
Abstract:Nomadics is a research and development company that has been quite successful in developing products for the biomedical market. The majority of our research involves the development of advanced materials that are being exploited for commercial applications. In this effort, we propose a novel… more
Abstract:The aim of this study is to develop a multiplexed virus detection platform capable of detecting within three hours the presence of any known virus, genetically modified virus or unidentified virus, in clinical samples like serum. A PCR based technique will be employed to identify the presence of… more
Abstract:The goal of the proposed research is to develop a highly sensitive, portable, vertebrate cell-based sensor for rapid detection of toxic chemicals in water that can be used as a standalone device or can be integrated into the ESB system. The key technological innovation that will be employed is a… more
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