Abstract:Aircraft maintenance, repair, and overhaul (MRO) organizations face the challenging task of scheduling maintenance work without knowing the full extent of the work content at the time of initial inspection. During the overhaul, new work is discovered requiring rapid re-sequencing of tasks and the… more
Abstract:Bovine Respiratory Disease is the most common illness among cattle arriving at feedlots and results in decreased weight gain, lower quality meat and death. BRD is highly transmittable and costs cattlemen more than all other diseases combined. A rapid and sensitive diagnostic method for BRD is not… more
Abstract:Attacks using chemical warfare (CW) agents are a principal threat to the US homeland and deployed assets. This proposal focuses on demonstrating key capabilities required to develop a micro-gas analysis (MGA) system that provides orders of magnitude improvement in sensitivity and a very high degree… more
Abstract:This Small Business Innovative Research (SBIR) Phase II project is to develop a novel material to enable improved performance of surface enhanced Raman spectroscopy (SERS). Availability of this material could result in the manufacture of pollution monitoring, industrial process monitoring, and… more
Abstract:In Phase I, Nomadics demonstrated that a novel chemical weapon indicating chromophore (CWIC) developed by Professor Tim Swager at MIT will allow equipment to be quickly and easily examined to show any areas of contamination, making targeted decontamination manageable. When exposed to CW agent… more
Abstract:Modern flight line engineers are faced with a large variety of sensor configurations. Different types of vehicles, and sometimes even different individual vehicles of the same type, have widely varying sensor loadouts. With current Instrumentation Support Systems (ISSs), each sensor configuration… more
Abstract:Current antibody-or enzyme-based chemical and biological sensors generally suffer from several disadvantages including involved development cycles, short shelf life, implementation difficulties, and no clear path for new receptor development. We propose an approach based on the use of… more
Abstract:The US military has a developed and is testing several technologies that promise to reduce fratricide incidents on the battlefield. These Radio-Based Combat Identification Systems consist of specially modified, currently inventoried, military radio systems. These systems do not allow… more
Abstract:This Small Business Innovative Research (SBIR) Phase II project will develop and introduce new low-dielectric constant polymers as a new dielectric material for the fabrication of interconnect systems in integrated circuits. The continuing drive for denser integrated circuits and faster… more
Abstract:Nomadics is a research and development company that has been quite successful in developing products for the biomedical market. The majority of our research involves the development of advanced materials that are being exploited for commercial applications. In this effort, we propose a novel… more
Abstract:The aim of this study is to develop a multiplexed virus detection platform capable of detecting within three hours the presence of any known virus, genetically modified virus or unidentified virus, in clinical samples like serum. A PCR based technique will be employed to identify the presence of… more
Abstract:The goal of the proposed research is to develop a highly sensitive, portable, vertebrate cell-based sensor for rapid detection of toxic chemicals in water that can be used as a standalone device or can be integrated into the ESB system. The key technological innovation that will be employed is a… more
Abstract:Optical circuits provide many benefits for large time-bandwidth signal processing in microwave photonic applications. SeTapped delay lines using surface acoustic waves (SAWs) are in use today for carrier frequencies in the MHz to 100 MHz range, and thus their general theory and efficacy are well… more
Abstract:Our goal is to detect and eliminate BW agents rapidly. In this project, we will develop functionalized nanoparticle photodynamic agents that can be bioconjugated with monoclonal antibodies to rapidly detect and kill viral infections. During Phase I, we will concentrate on the design and… more
Abstract:DESCRIPTION (provided by applicant): In an on-going collaboration with Drs. Angelo Russo and James B. Mitchell at the National Institute of Health, Nomadics has demonstrated the use of nanoparticles as fluorescence and spin contrast agents for optical and magnetic imaging simultaneously. In this… more
Abstract:Munitions and detonable residues of energetic materials in used munitions containers represent a significant safety hazard to operations personnel and equipment. Besides the possibility of containing unexploded munitions, munitions containers are contaminated with explosives residues ranging in… more
Abstract:Vesicants have been used as chemical warfare agents since World War I and are still considered a major class of chemical threat agents both for the military and for homeland security. There are four different vesicating agents: impure sulfur mustard, distilled sulfur mustard, phosgene oxime, and… more
Abstract:Painting metal provides excellent corrosion protection, as long as the paint remains intact. However, if the paint peels or becomes chipped after an impact, corrosion can occur in the revealed metallic area and even spread underneath the paint. Therefore, regular inspection and maintenance are… more
Abstract:Surface cleaning is extremely important in that it removes common surface contaminants such as loose metal oxides, oils, dirt, etc. that have deleterious effects on the wetting and adhesion of subsequently applied coatings. However, during the cleaning process, matrix dealloying and redeposition of… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project proposes development of a distributed optical fiber sensor using computationally designed fluorescent proteins. Surface plasmon coupled emission (SPCE) has been shown to be an excellent means to enhance fluorescence sensing technology. … more
Abstract:The goal of the proposed research is to develop a highly sensitive, high-throughput, and miniaturized assay system for rapid detection of brain injury-specific biomarkers in serum. The assay will be integrated into a portable detector so results can be immediately communicated to the health-care… more
Abstract:DESCRIPTION (provided by applicant): The primary goal of this research is to develop nanometer-sized, stable, highly fluorescent, nontoxic, and biocompatible conjugated polymer bioconjugates (CPB) for live cell imaging. The most commonly used fluorophores in cell imaging, cell tracking, and in vivo… more
Abstract:76293S With network bandwidth increasing more rapidly than processor speed for the past two decades, a serious performance problem exists for the transport, storage, and retrieval of large amounts of scientific data. This project will identify current performance bottlenecks, and develop a… more
Abstract:The capability to quickly assess and restore a damaged aircraft to a useful level of combat capability is vital to the United States Air Force. Open Solutions, Inc. proposes to develop a decision support system that makes use of airframe properties (impact location, load factor) and structural… more
Abstract:The U.S. Air Force Depot receives materials, parts, and components (MPC) for repair or refurbishment from a variety of sources across the globe including forward operating areas and combat zones. Current procedures and protocols call for decontamination of MPC at forward operating locations. … more
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