Abstract:DESCRIPTION (provided by applicant): Antibacterial resistant Staphylococcus aureus, in particular methicillin-resistant S. aureus (MRSA), infections constitute a serious worldwide health problem. MRSA infections are usually hospital-acquired, although the incidence of community-acquired infections… more
Abstract:Nomadics is currently working with a novel chemical weapon indicating chromophore (CWIC) that can make CW agent contamination literally glow in the dark. Developed by Professor Tim Swager at MIT, CWICs will allow equipment to be quickly and easily examined to show any areas of contamination, making… more
Abstract:75948-It is important to determine the fate and transport of contaminants generated from past weapons production and from current energy production activities. In support of this goal, this project will develop technology for the highly sensitive real-time detection of radionuclides in the… more
Abstract:None of the current chemical warfare (CW) agent sensors or field test kits has sufficient sensitivity to detect nerve and blister agents at allowable exposure level (AEL) concentrations. Thanks to a remarkable chromophore developed by Professor Timothy Swager at MIT, Nomadics believes that we can… more
Abstract:Nomadics proposes development of a system consisting of an Entrant Safety Unit (ESU), carried by the worker, and an Attendant Interface Unit (AIU) stationed at the entrance to a confined space. The units are in constant communication through a wireless link. The ESU periodically determines if the… more
Abstract:In this Phase I SBIR, Nomadics will build on our past experience with micro-structure resonators and quartz-based sensors to develop a pressure sensor suitable for high pressure applications such as oil and gas industry applications. In the Phase I work, the outstanding measurement resolution of our… more
Abstract:Modern flight line engineers are faced with a large variety of sensor configurations. Different types of vehicles, and sometimes even different individual vehicles of the same type, have widely varying sensor loadouts. With current Instrumentation Support Systems (ISSs), each sensor configuration… more
Abstract:Short range line-of-site communication is an integral part of the SOF mission. In nearly all regions where SOF operations take place, there is little if any short-range line-of-site communications infrastructure that can support these missions. The objective of this project is to design and… more
Abstract:DESCRIPTION (provided by applicant):
Nomadics proposes the development of scintillation nanocomposite materials that are capable of producing scintillation luminescence (SL) and the demonstration of their applicability for in vivo dosimetry and radiation dose imaging. Successful production of SL… more
Abstract:76010-For general illumination applications, the prospects for energy efficient solutions based on existing III-Nitride semiconductors appears to be constrained to less than 90 lumens. Further development of III-Nitride light-emitting diodes, both in device efficiency and in cost, are limited by… more
Abstract:Nomadics proposes the development of an x-ray system for use underwater. The proposed sensor is similar to a raster or "flying spot" backscatter imager. These systems operate by scanning an x-ray beam across a surface and monitoring the backscattered energy. There are two significant challenges… more
Abstract:Antibody-based receptor scaffolds used in chemical and biological sensors suffer from certain inherent shortfalls. We propose an approach based on the use of computationally designed proteins as receptor scaffolds. Such receptor scaffolds overcome many of the problems encountered with antibodies.… more
Abstract:Under funding from DARPA, Nomadics has demonstrated the potential for deploying multi-gun fixtures as a means of defeating rocket-propelled grenades (RPGs). These early tests have created a database that will be invaluable in advancing the work toward optimization of the initial concept through… more
Abstract:By mechanically attacking the nose/warhead of a rocket-propelled grenade (RPG), one can render the RPG into a purely kinetic projectile rather than an explosive one. This can be achieved by shearing the nose fuze, collapsing the ogive, or disrupting the explosive itself. While a 2.5 kg projectile… more
Abstract:The goal of the proposed research is to develop a cell culture model for elk chronic wasting disease (CWD) prion propagation that can be used as a bioassay for detecting CWD. Our goal will be accomplished by bioengineering a bovine B-lymphocyte cell (B-cell) line to surface express elk PrPc fused to… more
Abstract:Nomadics proposes to implement its proven Fido explosives detection system to produce a system specifically designed to identify the trace chemical signature of explosives on personnel who may be involved in the fabrication or transport of improvised explosive devices (IEDs), including suicide bombs… more
Abstract:High chemical activity of chlorine and severe health effects after even short-term exposure to it make facilities that use chlorine are subject for potential terrorist attacks. The magnitude of such attacks on U.S. chemical facilities could easily exceed the loss of life suffered on September 11th.… more
Abstract:All explosive devices, including IEDs, have chemical signatures that to date have been underexploited as a means of detction. Nomadics is proposing to employ chemical sensing methods to determine if suspected items contain explosive elements or not. Using the Fido ultra-trace detector as the core… more
Abstract:This Small Business Innovative Research (SBIR) Phase II project will develop and introduce new low-dielectric constant polymers as a new dielectric material for the fabrication of interconnect systems in integrated circuits. The continuing drive for denser integrated circuits and faster… more
Abstract:76293-With network bandwidth increasing more rapidly than processor speed for the past two decades, a serious performance problem exists for the transport, storage, and retrieval of large amounts of scientific data. The client of a clustered file system, which acts as the middleman between the Grid… more
Abstract:This Small Business Innovation Research Phase I project is a feasibility study of developing a terabyte size database server using advanced software technology developed for supercomputer cluster and scientific computation. With today.s rapid proliferation of information, organizations are facing… more
Abstract:R4 (Rapid, Reusable, Repeatable, Removable) tooling system. In this project a method of making and using a reusable mandrel, which can be made rigid for use as a tool for formation of the internal surfaces of composite parts, will be developed. This closed system makes it environmentally safe and… more
Abstract:RTA Systems, Incorporated and their teaming partner, Terra Environmental Products Company (TEPCO) propose to develop a novel, spray-applied, water-based, two-part liquid formulation that can effectively clean Chemical/Biological (CB) agents from the surface of materials/parts and components and… more
Abstract:DESCRIPTION (provided by applicant): Clinical practice guidelines recommend implementation of nighttime incontinence care that minimizes sleep disruption for nursing home residents. However, these guidelines offer no specific intervention recommendations. Investigators propose a method to… more
Abstract:DESCRIPTION (provided by applicant): Normal recruitment of circulating white blood cells (leukocytes) into tissues is important in inflammation, lymphocyte homing, and immunological responses. The mechanism of recruitment involves receptors termed selectins that recognize their counter receptors on… more
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