Abstract:DESCRIPTION (provided by applicant): Underage alcohol consumption is a public health concern with numerous negative sequelae, including adoption of other risky behaviors (smoking, other drug use, at-risk sexual behavior, drinking and driving), increased rates of depression or suicidal ideation, poor… more
Abstract:PROJECT SUMMARY This project aims to fill the urgent need for a safe and engaging intervention that promotes physical activity in a population of patients with chronic diseases (e.g., diabetes, asthma, osteoarthritis, and chronic heart failure). Compelling evidence suggests that physical activity… more
Abstract:PROJECT SUMMARY Depression and metabolic syndrome (MetS) are common chronic conditions that are debilitating to individuals and costly to employers and public and private payors.1-3 Unfortunately, they are often comorbid, each making the other more severe, more difficult to manage, and more costly… more
Abstract:DESCRIPTION (provided by applicant): Excessive alcohol consumption is a public health concern that causes approximately 80,000 deaths each year in the United States and costs the economy an estimated 223.5 billion in annual medical, social, and productivity losses. Because the large majority (79%)… more
Abstract:We propose to form a network and a set of tools that will create a shared situation awareness with Unmanned Aircraft Systems (UAS) Ground Control Stations (GCSs) and airline dispatchers at Airline Operations Centers (AOCs). Our solution is motivated by the Collaborative Decision Making (CDM)… more
Abstract:A Microchannel Sabatier Reactor System (MSRS) consisting of cross connected arrays of isothermal or graded temperature reactors is proposed. The reactor array enables nearly complete single pass carbon dioxide reduction using the Sabatier reaction, allowing efficient recovery of oxygen from in situ… more
Abstract:A microgravity-compatible Brine Evaporation and Mineralization System (BEMS) is proposed for 100% water recovery from highly contaminated wastewater as well as water generated from entrained organic contaminant oxidation without concern for precipitation of organic and inorganic solids. The BEMS… more
Abstract:Plasma techniques are proposed for the extraction of oxygen from the abundant carbon dioxide contained in the Martian atmosphere (96 % CO2). In this process, CO2 is directly decomposed in an energetic plasma forming O2 and CO, which are immediately separated. The Phase I project will clearly… more
Abstract:Microwave regenerative sorption media gas storage/delivery techniques are proposed to address both compressed gas management and hydrogen purification requirements in support of crewed deep space exploration missions. By reducing or eliminating the need for a conventional gas compressor, both the… more
Abstract:DESCRIPTION (provided by applicant): This Phase I proposal is to develop audio-tactile reading technologies. These should greatly improve access by blind people to typical graphs, charts, and diagrams in modern news, business, or scientific literature. Such access could dramatically improve their… more
Abstract:Many planned nextgeneration experiments in high energy physics, astroparticle physics, and nuclear physics need a plethora of photon detectors with singlephoton sensitivity, large dynamic range, and accessibility throughout experiment lifetime. These requirements constrain the sensor: low… more
Abstract:The need for ever more sensitive, compact, rugged, and inexpensive optical sensors is particularly acute in the fields of homeland security, biological sciences, nuclear medicine, and nuclear and highenergy physics. The ability to detect the spatial location and time of arrival of single photons… more
Abstract:The Arctic sea ice cover plays a major role in governing the exchange of energy between the ocean and atmosphere in the Polar Regions. As such, observations of ice extent and thickness, including temporal growth and melt cycles, improves our understanding of the ongoing global climate changes, and… more
Abstract:ABSTRACT: A fast, 1-cm diameter cylindrical gradient index (GRIN) nonlinear optical (NLO) refractive index lens, with large radial linear and nonlinear optical index gradients in all three optical axes will be fabricated using ink jet printing (IJP). The goal is to demonstrate the ability to… more
Abstract:ABSTRACT: Using roll-to-roll (R2R) -compatible inkjet-print (IJP) deposition and nanoimprint (NI) photolithographic patterning methods, a series of passive and electro-optic (EO) -modulated waveguide structures will be fabricated and characterized. The measured data will be compared to modeled… more
Abstract:ABSTRACT: High-yielding inkjet print (IJP) deposition technologies will be developed for hybridizing the ultra-small pitch semiconductor detector arrays and readout integrated circuits (ROIC). The goal is to develop a method, alternative to the thermocompression hybridization methods currently used… more
Abstract:The "piston errors" and aberrations of the mirror segments used in large telescopes, are typically measured with on-board optical instruments, usually a dispersed Hartman sensor (DHS) and/or dispersed fringe sensor (DFS). Calibrating and testing of the wavefront sensors are typically… more
Abstract:An optical communications receiver requires efficient and high-rate photon-counting capability so that the information from every photon, received at the aperture, is processed. This is particularly true in space platforms, where the information contained in every additional photon detected directly… more
Abstract:DESCRIPTION (provided by applicant): Yecuris has developed an in vivo genetic selection system (the FRG KO mouse) that permits extensive humanization of murine liver by transplantation with human hepatocytes. This model has many potential commercial applications in drug development and testing,… more
Abstract:DESCRIPTION (provided by applicant): Traumatic brain injury (TBI) is an acquired neurological disorder that can cause long-lasting disability with limited treatment options. Therefore, preventative strategies must be emphasized in high-risk activities toreduce the individual and societal burden… more
Abstract:Over one million women worldwide are diagnosed with breast cancer each year. Roughly 20% of all breast cancers overexpress the human epidennal growth receptor 2 (HER2-positive subtype). HER2-targeted therapies, including Herceptin and lapatinib, account for 55% of the breast cancer therapy market in… more
Abstract:ABSTRACT: Interest in tracking human movement has been motivated by the wide array of its applications in health care, military training, sports, and entertainment. Currently, there is no single motion capture technology that is perfect for every possible use. The most common method of tracking… more
Abstract:DESCRIPTION (provided by applicant): APDM is a young company focused on developing and commercializing professional systems using wearable inertial sensors for monitoring of human movement and movement disorders. In Phase I, we developed the novel, Instrumented Stand and Walk test (ISAW) using… more
Abstract:This SBIR Phase II project will result in a cloud-based web application that uses natural language processing to automatically generate online assessment questions for any digital textual material and to align questions with topics and learning outcomes. These questions will be available for… more
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