Abstract:The goal of this Phase I project is to develop an engineering plan and to create a prototype for a mobile, cloud-based expert system to aid in diagnosis, decision support and predictive analytics to improve clinical outcomes for veterans, soldiers, and their families with traumatic brain injury… more
Abstract:Inspired Light is developing a high-efficiency Concentrating Photovoltaic (CPV) system that requires accurate, 2-axis tracking. Available tracking systems are too large, expensive and require specialized setup procedures that are incompatible with a very low cost, versatile deployment strategy.… more
Abstract:Acute challenges are faced by the designers of fluid systems for spacecraft because of the persistently unfamiliar and unforgiving low-g environment. For example, most fluid systems aboard spacecraft are impacted by the presence of capillary forces?a poor understanding of which has led to poorly… more
Abstract:DESCRIPTION (provided by applicant): PROJECT SUMMARY Although prophylactic vaccines have potential for prevention of high risk human papilloma virus (HPV) infection they have no therapeutic efficacy. It has been estimated that there will be no measurable decline of HPV- associated tumors before 2040… more
Abstract:DESCRIPTION (provided by applicant): Type 1 diabetes often leads to short-term and long-term complications which impair quality of life. Though many research groups are developing versions of an artificial endocrine pancreas (AP) system, current systems require at least one hormone delivery… more
Abstract:The proposed effort to develop a modular Hybrid UAV Propulsion system whereby the best ICE or Turbine generator can be integrated as it is developed. Northwest UAV Propulsion Systems will work with AMRDEC and utilize the data collected on several EM and ESC that AMRDEC has tested over the last year.… more
Abstract:DESCRIPTION (provided by applicant): (Phase-2, Renewal) The SACC-Substance Addiction Collaboration Channel(R) platform is a new Collaboration, WEB-2.0 springboard specifically designed to structure and share information across the Behavioral/Mental Health Workforce community with the special… more
Abstract:DESCRIPTION (provided by applicant): The presence of islet-directed auto-immunity and associated circulating auto-antibodies, previously thought to be primarily characteristic of type-1 diabetes mellitus (T1DM), is now apparent in a proportion of individuals with putative type-2 diabetes (T2DM),… more
Abstract:DESCRIPTION (provided by applicant): Development of a phase 2 beta for demonstration in Tree Top juice processing plant of a Field Applicable Real-time Remote Monitoring Sensor Device capable of detecting multiple pesticides simultaneously in unfiltered juice, fluid or waste water. We propose to… more
Abstract:The QED team proposes a study of an independent seagoing barge that can be attached to and made a part of an INLS or commercial RRDF floating platform. The barge contains an active motion compensation platform supported by either a self-contained air cushion, hydraulic/mechanical apparatus or a… more
Abstract:DESCRIPTION (provided by applicant): The problem of overweight children with intellectual disabilities (ID) has many adverse medical and psychological effects and is of growing concern among professionals in the disability research and advocacy arenas. Toaddress this issue, we propose to develop… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project proposes to optimize and demonstrate the scale-up of nanostructured anti-reflective coatings (ARCs) to meet the specifications of solar energy customers using high-performance processes along with a novel solution-phase synthesis and… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project focuses on the further development of an advanced, mobile, easy-to-use, patient-oriented, advanced Home Hemodialysis (HHD) system that minimizes the use of water (less than 6 liters) and medical waste, and importantly, minimizes… more
Abstract:DESCRIPTION (provided by applicant): Volitional, coordinated movement depends on proprioception to the extent that a loss of proprioception can lead to a lifetime of dyscoordinated movement. Proprioception can be adversely affected by spinal cord injury(SCI), stroke, and traumatic brain injury… more
Abstract:DESCRIPTION (provided by applicant): Tobacco is the leading cause of preventable disease and death in the U.S. Although effective tobacco cessation medications exist, the impact of these medications is diminished by lack of adherence by the patient. Basedon our team's expertise in the use of… more
Abstract:DESCRIPTION (provided by applicant): There is a great need for anti-malarial drugs that are inexpensive and effective against drug-resistant strains. Malaria is one of the most important diseases worldwide, with over 225 million cases each year, and about800 thousand deaths. Most of these deaths… more
Abstract:DESCRIPTION (provided by applicant): The goal of this SBIR project is to design a cost-effective, lightweight, integrated, whole-head dense-array electroencephalography and near-infrared spectroscopy (dEEG/NIRS) brain imaging and data analysis system for non-invasive recording of brain activity in… more
Abstract:The purpose of the proposed work is to demonstrate the feasibility of a novel instrument for multi-channel nuclear Magnetic Resonance Imaging (MRI) at ultra-low field (ULF). The instrument will overcome issues involved with conventional MRI systems use in combat casualty care. It will also provide… more
Abstract:DESCRIPTION (provided by applicant): Clinical neonatal monitoring is also vital for diagnosis and prognosis of acute pathologies. One such pathology, neonatal intraventricular hemorrhage (IVH), is a common consequence of premature birth, with approximately30 percent of infants weighing less than… more
Abstract:We propose a hollow reservoir cathode to improve performance in ion and Hall thrusters. We will adapt our existing reservoir cathode technology to this purpose. Reservoir cathodes are the only emission sources that are capable of supplying the necessary current density (>5.0 A/cm2) and life… more
Abstract:DESCRIPTION (provided by applicant): This SBIR Phase II grant will support the commercial development of an injectable biological product candidate, a unique proprietary recombinant humanized anti-factor XI monoclonal antibody (AXIMAB), towards an investigational new drug (IND) application. The lead… more
Abstract:DESCRIPTION (provided by applicant): Thrombotic cardiovascular diseases including venous thromboembolism (VTE), deep vein thrombosis (DVT), myocardial infarction, and ischemic stroke, remain leading causes of death and disability in the U.S. Although effective antithrombotic agents are available,… more
Abstract:DESCRIPTION (provided by applicant): One of the underlying causes of acute ischemic stroke (AIS) is the thrombotic-thromboembolic occlusion of cerebral blood vessels. Early use of tissue-type plasminogen activator (tPA, Activase(R)), currently the only FDA-approved treatment for AIS, can promote… more
Abstract:The so-called"software crisis"is continuing unabated. It is all too common for a software project to create software that is hard to maintain, inefficient, bug-ridden, late, and over-budget. Software flaws resulting from this current state of affairs are no longer an inconvenience but… more
Abstract:DoD operations and infrastructure increasingly depends on software, which makes it an attractive target for our adversaries. Not surprisingly, deception plays a central role in most cyberattacks. To better protect these critical systems, we propose to design and build an"active… more
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