Abstract:Purpose: Prior research points to several features of technology-based math games that may be important for supporting the learning needs of students with or at-risk for disabilities. These include games that engage students in highly motivating narratives, provide focused foundational knowledge and… more
Abstract:DESCRIPTION (provided by applicant): Senior citizens typically fail to follow their prescribed medication regimens. Separate studies report that adherence to long-term therapy for chronic illness is less than 50 percent. Failure to take medicines as prescribed significantly increases the likelihood… more
Abstract:DESCRIPTION (provided by applicant): Tuberculosis (TB) disease, which results from infection with Mycobacterium tuberculosis (Mtb), is a leading cause of infectious morbidity and mortality in children lt 5 years old worldwide. In TB endemic regions, in which the vast majority of the world's… more
Abstract:DESCRIPTION (provided by applicant): Translational research in the field of liver disease has been limited by a shortage of large animal models, which in turn has limited development of new therapies for metabolic liver disorders, acute liver failure, chronic (cirrhotic) liver disease, an… more
Abstract:DESCRIPTION (provided by applicant): The FDA requires the use of human hepatocytes for preclinical drug testing by pharmaceutical researchers, but unfortunately the supply of these cells is severely limited. Currently, cadaveric donors and surgical liver resection specimens are currently the only… more
Abstract:DESCRIPTION (provided by applicant): Overdose on acetaminophen (more commonly known by the brand name Tylenol(R)), accounts for 56,000 emergency room visits and more than 450 deaths annually in the USA. Acetaminophen overdose can occur by a single event ofexceeding the recommended daily dosage.… more
Abstract:DESCRIPTION (provided by applicant): Traumatic brain injury (TBI) is an acquired neurological disorder that can cause long-lasting disability with limited treatment options. Therefore preventative strategies must be emphasized in high-risk activities to reduce the individual and societal burden… more
Abstract:DESCRIPTION (provided by applicant): Sepsis is a prevalent and life-threatening medical condition characterized by development of a dysregulated inflammatory immune response and associated tissue damage. This dysregulated inflammatory response is initiatedby activation of Toll-Like receptor (TLR)… more
Abstract:Buildings consume 40% of the primary energy used in the United States. Space cooling accounts for approximately 12.7% of that primary energy consumption. The cooling demand is determined largely by two external factors: the temperature and humidity of the outdoor air, and the amount of solar… more
Abstract:Farmers in the USA have largely depended on the European honey bee, Apis mellifera, for crop pollination. In recent years, Varroa mites, Tracheal mites, Nosema, Viruses and Colony Collapse Disorder have reduced the availability of honey bee colonies. This has created a critical need for additional… more
Abstract:The company estimates that if this new tank capability can be developed it has the potential to replace older helicopter tank systems and become the industry standard, included in mandated specifications for helicopter tanks by the USFS. The company estimates that new product sales of the resulting… more
Abstract:Northwest UAV Propulsion Systems proposes using our purpose built heavy fuel engine designed and built in the USA for small unmanned aerial systems in the tier 2 & 3 class. We will be adding a lightweight ceramic material set combined with FEA (Finite Element Analysis) and heavy fuel atomizer (IRAD… more
Abstract:DESCRIPTION (provided by applicant): The SACC-Substance Addiction Collaboration Channel(R) platform is a new Collaboration, WEB-2.0 springboard specifically designed to structure and share information across the Behavioral/Mental Health Workforce commun
ity with the special focus on… more
Abstract:DESCRIPTION (provided by applicant): The application's broad, long-term objectives are to develop a rapid, high-throughput clinical assay for 3' fibrinogen that will be used to assess the risk of a patient developing venous thromboembolism. This assay will
guide clinical management, particularly… more
Abstract:DESCRIPTION (provided by applicant): The twin epidemics of obesity and diabetes threaten to overwhelm healthcare systems in the U.S. and worldwide, with almost 29 million Americans currently having frank diabetes (predominantly type-2; T2DM) and an additio
nal 68 million with prediabetes. There is… more
Abstract:DESCRIPTION (provided by applicant): Development of a Field Applicable Real-time Remote Monitoring Sensor Device Capable of Detecting multiple pesticides simultaneously in fluid or surface water. We propose to use carbon nanotube matrices as the active bio
sensor area for the effective… more
Abstract:Ultrasound is a standard of care for Central Line Placement (CLP). Existing transducers are awkward to use or require a second clinician to image. Fast and easy to use ultrasound guidance is especially important for military applications where every minute can mean a saved life or salvaged limb.… more
Abstract:In this Phase II research, Blacktoe Medical will design, manufacture and test a finger-worn ultrasound-imaging probe, optimized for Army vascular access requirements. The vascular finger probe will simplify use and reduce the time to learn complicated ultrasound guided procedures. By leveraging… more
Abstract:This Small Business Innovation Research Phase I Project will develop new analytical methods for lithium-ion batteries (LIBs) to enable significantly greater safety and performance of batteries. Combing impedance spectroscopy testing with physical analysis, the methodology will identify specific cell… more
Company:Lao K LLCAgency/Program/Year/Phase:EPA / SBIR / 2010 / 1
Abstract:Interior wood composite panels are widely used for furniture, bookshelves, kitchen cabinets, and flooring, and are predominately made with carcinogenic urea-formaldehyde (UF) resin. A new formaldehyde-free, environmentally friendly wood adhesive that mainly consists of abundant, renewable and… more
Abstract:The QED team's design approach comprises a rapidly deployable breakwater, causeway and anchoring system. The study focuses on the systems integration of these elements with emphasis on delivery means and installation to meet the 48 hour readiness objective. This study builds on the QED team's… more
Abstract:DESCRIPTION (provided by applicant): An overlooked, neglected, yet significant problem in the United States today is the use and abuse of tobacco, alcohol, and other drugs by individuals with intellectual disabilities (ID). Increasing numbers of people wit
h ID are living independently in the… more
Abstract:This Small Business Technology Transfer (STTR) Phase I project aims to fabricate anti-reflective coatings (ARC) for solar energy applications. The approach is to use a convective and evaporation-induced assembly to deposit organized nanostructures and create sub-wavelength quasi repeating… more
Abstract:Utility companies have made huge investments in large capacity coal-fired power plants. The political winds are shifting, however, resulting in more and more pressure on utilities to reduce reliance on the use of coal with its resulting CO2 greenhouse gas missions. These utility companies… more
Abstract:ParaTools, Inc. will leverage its tools and expertise in scientific software performance evaluation to create an advanced, horizontally-integrated framework called IQB for the fast, scalable collection and retrieval of information about software program symbols and symbol interdependency. The… more
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