Abstract:DESCRIPTION (provided by applicant): Diffuse large B-cell lymphoma (DLBCL) represents one of the most common variants of Non-Hodgkin's lymphoma (NHL), and oncogenic herpesviruses (EBV and KSHV) are the etiologic agents for the majority of these tumors in patients over 50 or those infected with… more
Abstract:Towed array vector sensors are important for US submarine capability in terms of reducing the left right ambiguity. Current towed array vector sensors use particle velocity sensors or accelerometers combined with hydrophones to achieve this performance. Lead magnesium niobate-lead titanate (PMN-PT)… more
Abstract:ChemImage Sensor Systems (CISS), teaming with the University of South Carolina, proposes a revolutionary wide-field Raman hyperspectral imaging system capable of meeting the stated needs. The proposed innovation couples a spatial heterodyne spectrometer (SHS), a novel slit-less spectrometer that… more
Abstract:ABSTRACT: One of the key lessons learned from operations Iraqi Freedom and Enduring Freedom is that Close Air Support (CAS) is assuming an increasingly important role for US military planners and field commanders. Joint Terminal Attack Controllers (JTAC) play a critical role across all Services in… more
Abstract:Today, as humans reach beyond the earth to near and deep space, there is obvious and urgent need to augment the capabilities of human astronauts and (ground-) controllers with smarter and more capable automation. In conventional approaches to human-robot interactions for supervisory control… more
Abstract:The Acoustically Synchronized Store Ejection/Release Technology (ASSERT) test process was developed by CRAFT Tech. This research has produced a capability to conduct small scale dynamic drop tests instrumented with stereo-photogrammetry to track store motion and synchronize this with unsteady… more
Abstract:As air vehicle speeds increase, air breathing engine and inlet technology follow through concurrent supersonic performance requirements. The recent ability to build smaller supersonic engines has established a void in small air vehicle inlet capability. A solution to decrease the overall footprint… more
Abstract:The overall goal of this STTR program is to develop an efficient, high-fidelity, CFD-based design tool for the simulation of ship-board flight testing of autonomous UAV systems. In the first phase of this program, an overall flight simulation framework that employs a modular approach to the flight… more
Abstract:CRAFT Tech proposes the development of an innovative design optimization tool called"AeroRCS"which will simultaneously solve for both aerodynamic performance as well as electromagnetic reflectivity (Radar Cross Section). When operated in an automated environment, AeroRCS will… more
Abstract:Proposed effort will formulate and demonstrate the methodology for fabricating Porous Ceramic Matrix Composite (PCMC) transpiration plates with controlled levels of porosity, suitable for high-speed/high-temperature missile applications. Process will entail subjecting polymer composites to… more
Abstract:ABSTRACT: The need for evaluation of aerodynamic loads on internal weapons bay doors comes from the US Air Force's requirement to open doors on many of its aircraft during flight. This ranges from an aircraft's low-speed opening of landing gear doors and speed brakes to opening weapons… more
Abstract:ABSTRACT: The innovation proposed is a computationally-tractable, physics-based, portable turbulent combustion modeling strategy for application to a wide range of Air Force aero-propulsive systems, including augmentors, liquid rockets and scramjets. This modeling strategy will be implemented… more
Abstract:A validated, advanced, detailed physics-based CFD capability to accurately model the separated flow physics immediately downstream in the base region of a propulsive supersonic/hypersonic missile with plume afterburning is developed. The high levels of tu
Abstract:ABSTRACT: Next generation liquid rocket systems, envision novel designs for cryogenic turbopumps that exhibit high suction performance with low inlet pressures, operate at high tip speeds to reduce size and weight, and can be throttled over a wide range of low, off-design flow conditions where the… more
Abstract:Historically, aircraft engines have featured relatively simple axisymmetric exhaust shapes with several moving parts; however, future engine exhaust systems are expected feature compact, sinuous ducts with complex non-axisymmetric shapes, fixed exit areas, thrust vectoring etc., constructed with a… more
Abstract:Aeroelasticity plays an important role in the design and development of highly flexible flight vehicles and blended wing body configurations. The operating margins on these flight systems are limited by non-linear unsteady phenomena such as stall, flutter, gusts, limit cycle oscillations, vortex… more
Abstract:This Phase II proposal describes a networking solution that addresses the requirements of next generation SIGINT systems that will be deployed on submarines. The system consists of a multi-protocol, multi-terabit fabric interconnect with reduced size, weight, and power compared to other currently… more
Abstract:In this Phase II SBIR project, Daniel H. Wagner Associates will develop a full-scale prototype Air Combat Identification (ACID) Module that will improve the accuracy of Track Management or Data Fusion systems when attempting to estimate the identity or classification of an Air target. The… more
Abstract:In this SBIR project Wagner Associates, with Marine Information Resource Corporation (MIRC) as a subcontractor, will develop an Efficient Autonomous Sensor Performance Prediction (EASPP) system that will automatically and autonomously: (1) Generate the minimal number of required Transmission… more
Abstract:In this SBIR project Wagner Associates will develop Automated active Sonar Interference Avoidance algorithms (ASIA) that will automatically produce a recommended Active Sonar Interference Avoidance Plan (ASIAP). ASIA assisted automated and accurate sonar interference avoidance planning will: (1) … more
Abstract:In this SBIR project Wagner Associates will develop Passive sonobuoy Association, Classification, and localization (PAC) algorithms to maximize the effectiveness of current and emerging passive sonobuoy patterns and to minimize operator task load when monitoring these fields. In particular, we will… more
Abstract:In this project, we will develop innovative and advanced display and processing techniques, and innovatively combine existing algorithms, software, and systems, to create a Detection Avoidance System for Submarines (DASS) that assists the submarine operator, planner, and commanding officer (CO) in… more
Abstract:DESCRIPTION (provided by applicant): Post-transcriptional RNA modification plays an important role in biological processes. For example, adenosines to nosiness or A-to-I editing are most abundant in the central nervous system (CNS) and essential for normalCNS development. Presently, the available… more
Abstract:DESCRIPTION (provided by applicant):. Hemoglobinopathies are the most common monogenic diseases with approximately 7% of the world's population being carriers. Sickle cell disease (SCD) and thalassemia are primarily hemoglobin disorders. The current SCD diagnostic methods require expensive… more
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