Abstract:ABSTRACT: The K-128 co-processor leverages insights from neuroscience to achieve superior performance. Unlike previous efforts along those lines, our approach is to create a software programmable co-processor that runs existing applications. One of the most salient characteristics of such a… more
Abstract:The program delivers a completely new technology solution to isolation and sensing of power flow (current and voltage). Based on striction materials technology, these small isolation and sensing devices replace Opto-isolation, Hall-effect and Magnetic Transformer isolation and sensing with a lower… more
Abstract:The goal of the Phase I effort is to design, develop and demonstrate a novel solid-state ceramic-based voltage isolator and demonstrate its potential to provide a highly radiation tolerant digital voltage isolation solution applicable to a wide range of NASA mission requirements. The related design… more
Abstract:The primary objective of the Phase I investigation is to develop and demonstrate an innovative solution that can enable very high precision pointing accuracy (<0.08 degree nominal;<0.03 degree extended goal) at fast slew rates; providing part of a advanced Smallsat/CubeSat precision attitude… more
Abstract:DESCRIPTION (provided by applicant): Infection is a common and frequently very serious complication associated with medical implants. Man-made materials, including those used to fabricate ventricular assist devices (VADs), compromise the body's ability tofight infection in tw ways. First, by… more
Abstract:Currently available hull thickness sensors use ultrasonics and provide coverage of a single point on the hull. The sensor must then be moved over the hull while the thickness readings are monitored to detect thin areas of hull plate. These systems generally contain array type sensors; however, they… more
Abstract:Reliable monitoring of the microcrack formation in the complex composite structure components in NASA spacecraft and launch vehicles is critical for vehicle operations. Early diagnosing and reporting vehicle capability has tremendous impact on mission readiness, safety, and life cycle cost.… more
Abstract:The broader impact/commercial potential of this Small Business Innovation Research Phase II project is significant. The purpose of this project is to create new ingredients which reduce the toxicity profile of personal care and cosmetics products. This project will achieve this by inventing and… more
Abstract:The proposed program will produce graded composites consisting of a new thermoplastic resin with excellent properties leading to higher heats of ablation, low thermal conductivity and lower heat shield weight. This structure can eventually serve as an integrated Thermal Protection System (TPS)… more
Abstract:DESCRIPTION: While HIV/AIDS can be managed with antiretroviral drugs that block viral replication, these agents do not clear the virus and require life-long drug administration with associated risks of cumulative toxicity and drug resistance. Recently, wediscovered a completely new class of… more
Abstract:We have discovered the first-ever inhibitors of PF4, a platelet protein central to the pathophysiology of heparin induced thrombocytopenia (HIT). Heparin is a naturally-occurring anticoagulant that prevents the formation of clots and extension of existingclots within the vasculature, and major… more
Abstract:DESCRIPTION (provided by applicant): Systemic fungal infections are increasingly common, especially in immune compromised patients. While new antifungal drugs have been developed, there is still a high mortality associated with these infections, especiallythose due to Candida albicans, other… more
Abstract:ABSTRACT: It is challenging for analysts and operators to maintain effective situational awareness for the task at hand in an environment of ubiquitous and seemingly unending data spanning text, video, and other mediums. Intuidex proposes research and development of a solution to this challenge… more
Abstract:DESCRIPTION (provided by applicant): Most current chemotherapeutics have non-specific mechanisms of action and poor biodistribution profiles which result in dose-limiting toxicities tha prevent optimal efficacy from being obtained. Ribonucleic acid interference (RNAi) has the potential to be a safe,… more
Abstract:Hook and loop closures in Army uniforms have been identified as the critical sources of leaks in protective clothing/equipment, which limits the overall protective capability of the ensemble. We demonstrated during Phase I of this project that we can design and fabricate hybrid closure systems which… more
Abstract:DESCRIPTION (provided by applicant): Ion channels, such as Kv1.3 and Nav1.7, are involved in a number of human disorders, including autoimmunity and pain that affect gt100 million Americans annually and are poorly treated. However, ion channels are typically exceptionally difficult to express at… more
Abstract:DESCRIPTION (provided by applicant): Cells require the ability to detect and respond to stimuli in their surroundings, including to endogenous metabolites, exogenous nutrients, and environmental irritants. The proteins that are responsible for this processare called chemosensors and are involved in… more
Abstract:ABSTRACT Acute and chronic pain resulting from injury, surgery, or disease afflicts gt100 million Americans each year, having a severe impact on mood, mental health, and quality of life and costing the U.S. approximately 600 billion in economic costs annually. For many patients, treatment options… more
Abstract:Current prosthetic technologies allow amputees to return to a form of normal life, but create new risks, such as improper socket fit, which can lead to a heightened risk for tissue damage that could result in infection and hospitalization. These risks could be minimized by using a sensor system to… more
Abstract:This proposal addresses the opportunity to develop an optimized power and data bus for aircraft rotor loads monitoring by offering an innovative solution that delivers high power density energy harvesting and reliable delivery of large volumes of data from a rotating frame to a fixed frame. The… more
Abstract:This Phase II SBIR proposal responds to a need for adaptive compliant actuator hardware that can adapt to a wide range of applications for human-robot interactions. Some tasks require high forces to lift, pull, or carry and other tasks require fine motor control and precise motion. Human-robot… more
Abstract:KiON Defense Technologies, Inc. (KDT) has teamed with Lockheed Martin Aeronautics Company (LM) and Materials Research & Design, Inc. (MR & D) to demonstrate the effectiveness of a low areal density Thermal Protection System (TPS) for Navy reentry bodies. The new TPS system will incorporate… more
Abstract:Per the topic description, dense maritime environments pose significant challenges to naval airborne sensor systems with respect to surface target classification, track lifetime, and track association. A promising strategy to drastically improve situational awareness and reduce operator workload in… more
Abstract:Conventional CFAR detection processing has difficulty in heterogeneous clutter (i.e., maritime clutter) because the fixed data size windowing is not well matched to the spatial scales of the wave field over a wide range of sea states. The non-Gaussian nature of heterogeneous clutter gives rise to… more
Abstract:er the topic description, naval airborne sensor systems are utilizing or are planning to utilize varying degrees of automation in the prosecution of their missions as part of future naval capabilities. The automation must handle very dense maritime surface picture conditions that can exceed 1,000+… more
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