Abstract:Development of semantic technologies to support materials design and development. This project is intended to start constructing the building blocks for 1. Common Vocabulary Development, 2. Annotation, exposure, and discovery of existing published material properties and processes using standard… more
Abstract:ABSTRACT: RJ Lee Group, Inc., in partnership with experts from Hamler Test and Analysis, Inc., and in collaboration with GE Aviation, proposes to develop a Decision Support Tool (DST) to model the cumulative effects on component service life by CMAS (calcium-magnesium-aluminum-silicon oxide) on jet… more
Abstract:The need exists for an autonomous Tactical Decision Aid (TDA) tool which can be used to optimize the effectiveness of Multi-Static Anti-Submarine Warfare (ASW) mission performance. The tool must make use of the most up-to-date and accurate environmental data obtained in real-time over a network… more
Abstract:U.S. Navy ASW aircraft deploy sonobuoys across a mission field. The aircraft must then stay on-station for the duration of the mission to monitor, command, and received data from the deployed sonobuoys. This requires a clear and uninterrupted channel of communications during all command downlink and… more
Abstract:DESCRIPTION (provided by applicant): The overarching objective of this study is to engineer solutions to allow people with severe disabilities who require assistance (human or mechanical) while transferring to be able to transfer in their homes, homes offriends/family, and in the community at large… more
Abstract:An innovative, new adaptive signal processing solution is proposed for mitigation of the impact that wind turbine clutter has on airborne radar performance. Electromagnetic simulations are used to predict radar returns in the presence of wind turbine scattering, terrain multipath, and clutter from… more
Abstract:DESCRIPTION (provided by applicant): Heart disease is the leading cause of death for both men and women in the US, accounting for nearly 40% of all annual deaths. A high cholesterol level is well-known risk factors for heart disease. Although blood cholesterol can be lowered using a number of… more
Abstract:Wick properties are often the limiting factor in a heat pipe design. Current technology uses conventional sintering of metal powders, screen wick, or grooves to fabricate realtively simplistic wick geometries. Additive manufacturing (laser sintering) of a porous structure would allow much greater… more
Abstract:Looking Glass is an immersive, story-driven game experience that enables computer science education for students K-12. It presents learning in a game-based series of challenging levels that permit a high degree of player choice in tailoring educational pr
Abstract:The frictional losses in a gear mesh can be reduced by including super-finishing in the final manufacturing process. Phase I simulation tests of a hypoid rear axle gear shows a reduction in traction coefficient of 50 percent from an"as ground"surface to a high quality super-finished… more
Abstract:ABSTRACT: Incomplete and inconsistent impregnation of fiber beds in composite material manufacture jeopardizes the performance of multiple aircraft platforms and substantially increases acquisition and sustainment costs for the Air Force. Current test methodologies are inadequate to address this… more
Abstract:Because Critical Program Information (CPI) is often embedded in Integrated Circuits (ICs), adversaries must now attack at the die level or through other intrusive means. As a result, Focused Ion Beams (FIBs) have become a preferred tool for reverse engineering. In Phase I, Nokomis demonstrated that… more
Abstract:The primary objective of this Phase II is to develop more complete part class coverage for the ADEC system. During Phase I, Nokomis demonstrated ADEC"s authentication capabilities. ADEC detects counterfeits through automated analysis of unintended radiated emissions that are characteristic of… more
Abstract:National Aeronautical and Space Administration's (NASA) Aviation Safety Program "seeks capabilities furthering the practice of proactive safety management." Specifically, one of the key interests in Topic A1.04 are proposals for Remaining Useful Life prediction techniques. In… more
Abstract:The design concepts being considered for Heatshield for Extreme Entry Environment Technology (HEEET) rely on the use of 3D woven carbon fiber preforms. Therefore, there is a need to be able to predict the properties and performance of a woven material. Validation of predictive modeling tools would… more
Abstract:As the power density of advanced engines increases, the need for new materials that are capable of higher operating temperatures, such as ceramic matrix composites (CMCs), is critical for turbine hot-section static and rotating components. Such advanced materials have demonstrated the promise to… more
Abstract:The Climate Change Information System for Business and Industry (Climate Biz) will translate information derived from climate model simulations into industry-specific formats that will assist private sector executives and their firms to meet the challenge of climate change and thereby prosper in the… more
Abstract:DESCRIPTION (provided by applicant): Optofluidics Inc. proposes to develop a near field optical chromatograph, the BioPrism, and apply it to the characterization of particle coating stability in nanomedicine. According to clinicaltrials.gov, about 10% of all clinical trials involv nanoparticles and… more
Abstract:This SBIR Phase I project proposes to develop and commercialize an online video-sharing platform that scales math teacher education and training. The platform embeds a novel pedagogical method that combines gamification, algorithm-based peer review processes, and social learning technologies. The… more
Abstract:DESCRIPTION (provided by applicant): Lyme disease (LD) is the most commonly reported tick-borne illness in the United States. According to the recent Center for Disease Control and Prevention report, approximately 300,000 Lyme cases are diagnosed each year. If left untreated, the infection spreads… more
Abstract:DESCRIPTION (provided by applicant): Adenosine to inosine or A-to-I RNA editing executed by ADAR family proteins is abundant in the central nervous system (CNS). The availability of tools to monitor and manipulate both ADAR enzymes and A-to-I RNA modifications will facilitate investigation of the… more
Abstract:DESCRIPTION (provided by applicant): Monoclonal antibodies are used for treatment of a wide range of diseases from cancer to infectious diseases. However, development of antibodies with high affinity and specificity is still time-consuming, labor-intensiveand unpredictable. Abzyme Therapeutics LLC… more
Abstract:DESCRIPTION (provided by applicant): Broad-spectrum, orally bioavailable -lactam antibiotics play a critical role in the management of human infectious diseases, both in the hospital and community settings, facilitating exit from the ICU and treatment inthe general ward, early discharge and/or… more
Abstract:Abstract: This is a Phase II application for continued development of the Chemalytics Platform, a scalable computational infrastructure to enable virtual screening of chemical libraries using the Amazon EC2 cloud computing environment and automated dockingtools. Structure-based virtual screening is… more
Abstract:DESCRIPTION (provided by applicant): AMPA glutamate receptors mediate the majority of fast excitatory neurotransmission in the central nervous system. Four AMPA receptor subunits exist, GluA1-GluA4, with functional channels containing various combinationsof these four subunits. Dysregulation of AMPA… more
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