Abstract:The program will leverage recent advances in striction materials and coupled striction devices as to enable highly isolated (analog) voltage and current flow sensors very suitable for harsh space environment power monitoring. Exhibiting negligible electromagnetic disturbance coupling and… more
Abstract:DESCRIPTION (provided by applicant): Infection is a common and frequently very serious complication associated with medical implants. Man-made materials, including those used to fabricate ventricular assist devices (VADs), compromise the body's ability tofight infection in tw ways. First, by… more
Abstract:Since 1990, Prime Synthesis, Inc. (PSI) has been a leading manufacturer of controlled pore glass (CPG). It has developed significant expertise in the optimization of physical characteristics and chemical modifications of CPG for a variety of applications. CPG has a unique combination of attributes… more
Abstract:ABSTRACT: During Phase I, FBS, Inc. developed and demonstrated a light-weight, low-power, non-thermal, ultrasound-based ice protection system for RPA wing leading edges and other metallic and composite components requiring ice protection. Low-profile, light-weight, low-power ultrasonic actuators… more
Abstract:This Small Business Innovation Research Phase I project is directed towards the development of a non-ionic thickening agent for personal care products, which does not contain poly(ethylene glycol) (PEG). Reports have stated that commercially available PEG contains small levels of undesirable side… more
Abstract:DESCRIPTION (provided by applicant): The overall goal of this application is to develop and validate a potential biomarker based assay to determine if it can be used as a noninvasive test to detect the stage of hepatic fibrosis and to predict fibrosis progression in HIV/HCV co-infected patients.… more
Abstract:DESCRIPTION (provided by applicant): This is a phase I proposal to determine the feasibility of developing newly discovered fluorinated sulfamoylbenzamide (FSBA) derivatives as therapeutic agents for the treatment of chronic hepatitis B virus (HBV) infection. These molecules have been identified as… more
Abstract:DESCRIPTION (provided by applicant): This is a proposal to implement a novel high throughput assay system to detect inhibitors of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) formation and/or maintenance. HBV cccDNA is essential to the virus life cycle and its elimination during… more
Abstract:DESCRIPTION (provided by applicant): DC-SIGN (dendritic cell specific ICAM-3-grabbing non-integrin), a membrane protein of C-type lectin family, is found in high levels on monocyte-derived DCs, some macrophages, and activated B cells. In vivo, DC-SIGN- positive cells were demonstrated in lymph nodes… more
Abstract:DESCRIPTION (provided by applicant): Acinetobacter are strictly aerobic, non-fermentative Gram-negative bacilli that are of major concern in human health, in particular the species Acinetobacter baumannii. They are responsible for clinically important infections that cause a wide variety of maladies… more
Abstract:DESCRIPTION (provided by applicant): We have identified a novel Type IIb prodrug of riluzole, FC-311, which has the potential to revolutionize therapy for the treatment of the devastating condition of metastatic melanoma acting via a novel glutamatergic mechanism of action, and also be useful to… more
Abstract:Valuable time is spent by astronauts performing simple, mundane, or ergonomically taxing tasks. Therefore, one center of focus for NASA is to have robots increasingly perform these tasks to give the crew more time flexibility. Robots are also employed with tasks that are too dangerous for humans or… more
Abstract:Hook and loop closures in Army uniforms have been identified as the critical sources of leaks in protective clothing/equipment, which limits the overall protective capability of the ensemble. New closure systems capable of providing both the shear and peel strengths demonstrated by hook and loop… more
Abstract:KCF proposes to build a general wireless hearing protection device validation system with miniature, wireless in real ear microphones. The microphones will be battery-free to enable the reduction in size necessary to fit in the canal for testing with any hearing protection device. KCF has… more
Abstract:KCF in partnership with Penn State will evaluate and demonstrate a new generation of intrinsically safe robotic actuators built up from micro-actuator module units. The technical approach is based on state-of-the art prosthetic development where the human-mechanism interface is the primary focus. … more
Abstract:This proposal addresses the opportunity to develop an optimized power and data bus for aircraft rotor loads monitoring by offering an innovative solution that delivers high power density energy harvesting and reliable delivery of large volumes of data from a rotating frame to a fixed frame. The… more
Abstract:The embedded rotor load monitoring system developed under this SBIR project principally consists of Smart Rod Ends and a wireless base station. The Smart Rod Ends are conventional push rod ends that have an energy harvester powered wireless sensor system built into the shank of the rod end. The base… more
Abstract:Kion Defense Technologies, Inc. (KDT) has teamed with multiple CMC producers and an engine OEM to develop and demonstrate the effectiveness of a new, integrated matrix system for SiC-based composites for use at 1300oC (2400oF). Based on feasibility demonstration during the Phase I effort, KDT will… more
Abstract:The proposed Phase 2.5 effort will extend the Phase 2 results to airborne data collected at operational altitudes consistent with the current ASW mission profile. The proposed effort will also be extended to include airborne data collected at altitudes above the current ASW mission profile in an… more
Abstract:Per the topic description, naval airborne sensor systems are utilizing or are planning to utilize varying degrees of automation in the prosecution of their missions as part of future naval capabilities. The automation must handle very dense maritime surface picture conditions that can exceed 1,000+… more
Abstract:Detection, tracking and identification of targets, and subsequent prosecution is very challenging in dynamic environments. Traditional methodologies rely on an operator to analyze all the available information to identify what is actionable, and subsequently modify asset tasking. The operator… more
Abstract:In support of the Missile Defense Agencys Interceptor Missile Program, LithChem Energy (LCE) proposes its MDA Phase II Advanced Power Storage System for Interceptors. LCEs Interceptor Missile Lithium Reserve Battery Program and the successful completion of its MDA SBIR Phase I, resulted in the… more
Abstract:Among the factors that inhibit the use of composite materials in both general aviation aircraft and DoD platforms are the high cost of engineering and the cost of certification. Unless manufacturers can control risk when introducing new materials and pro
Abstract:ABSTRACT: Development and use of new composite materials is imperative for continued advancement of airframe and engine systems. In order to facilitate the accelerated insertion of new composite materials, there is a need for an improved analysis methodology that allows designers to reduce the… more
Abstract:The Navy is developing high speed projectiles for a variety of missions including ship defense, surface fire support, and prompt global strike. Inertial loads and high muzzle velocities impose severe operational conditions on the nosetips and suggest they should be made from refractory metals. While… more
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