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State:Rhode Island
Company: MULTICELL TECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant):
Sepsis is the systematic and overwhelming response to infection. Once triggered, an uncontrolled cascade of coagulation, impaired fibrinolysis, and inflammation drive disease progression. This results in damage to the lungs, liver, kidney and cardiovascular… more
Company: PRO-CHANGE BEHAVIOR SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 2
Abstract: DESCRIPTION (provided by applicant): Obesity is recognized as a major public health concern and has become a national health priority. With the prevalence of adolescent obesity nearly triple what it was two decades ago, effective interventions to prevent and treat overweight and obesity among… more
Company: PRO-CHANGE BEHAVIOR SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): Unhealthy eating, lack of exercise, and poor stress management habits are started in adolescence and have been shown to initiate or promote chronic diseases. Well-designed health promotion programs are needed to assist college students in shaping a foundation of… more
Company: PRO-CHANGE BEHAVIOR SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): Male-to-female intimate partner violence accounts for 26% of violence-related injuries in women presenting in hospital emergency departments and 30% of all female homicides. Early to mid-adolescence provides an excellen
t window of opportunity for the… more
Company: PROTHERA BIOLOGICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant) The overall goal is to develop a marketable novel predictive marker based on inter-alpha inhibitor proteins (laIp) in cerebrospinal fluid (CSF) that can be utilized in the management of CNS cancer. Cost effective care, successful palliation of symptoms and new… more
Company: PSYCH PRODUCTS PRESS Agency/Program/Year/Phase: HHS / SBIR / 2005 / 2
Abstract: DESCRIPTION (provided by applicant): Pathological gambling (PG) is a serious public health problem affecting at least 1% of the adult population in the U.S. By extension, it impacts families, business; and communities. Publicly funded-mental health services for pathological gamblers (PGs) exist in… more
Company: QUALITYMETRIC, INC. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): The project introduces a new approach to standardizing disease-specific assessments of Health-Related Quality of Life (HRQOL) to achieve the advantages of both generic questionnaires, which can be compared across which have greater sensitivity and specificity.… more
Company: QUALITYMETRIC, INC. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): We seek to achieve major advances in the standardization of chronic pain assessments and in the technology used to collect, process and display results. We propose to use: (1) item response theory (IRT) to calibrate widely-used visual analogue (VAS) and… more
Company: CELLCURE, INC. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): Ex vivo bioengineering of skeletal muscle tissue (BioArtificial Muscle, BAM) is currently aimed at two potential clinical applications following implantation in vivo: 1) to perform directed work to augment endogenous muscle force generation; and 2) to chronically… more
Company: AFFERENT CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): More than 10 million individuals in the U.S. are thought to suffer from diabetic neuropathies. Many serious medical problems stem from this condition, including degradation of the mechanical senses of touch and proprioception. Usually affecting the extremities… more
Company: AFFERENT CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): Stroke survivors constitute one of the largest groups of patients receiving rehabilitation services in the United States. The inability of most stroke survivors to regain full sensorimotor function significantly impacts quality of life while generating tremendous… more
Company: AFFERENT CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): Stroke survivors constitute one of the largest groups of patients receiving rehabilitation services in the United States. The inability of most stroke survivors to regain full sensorimotor function significantly impacts quality of life while generating tremendous… more
Company: Applied Plastics Technology, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2004 / 1
Abstract: 75336-A broad category of experiments in astro-particle and high energy physics requires the construction of ultra-high-purity and ultra-low-radioactive-background, cubic-meter-scale vessels to be used as containers for ionization and scintillation media. Double-beta decay experiments, solar… more
Company: APPLIED RADAR, INC. Agency/Program/Year/Phase: DOD / SBIR / 2004 / 2
Abstract: A W-band digital communications transceiver will be developed with 5 GHz instantaneous bandwidth utilizing the 71 - 76 and 81 - 86 GHz frequency spectrum recently allocated by the FCC. This project has both military and commercial applications for SATCOM and Point-to-Point digital communications… more
Company: APPLIED RADAR, INC. Agency/Program/Year/Phase: DOD / SBIR / 2004 / 2
Abstract: An X-band digital transmit module will be developed that is suitable for phased-array radar and communications applications. This proposed Phase II SBIR will combine our Phase-I X-band transmit module design with a DBF receiver that Applied Radar is developing through separate (non-SBIR) funding… more
Company: BCR DIAGNOSTICS Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): BCR Diagnostics, Inc. (BCR) proposes to study the feasibility of applying its low-cost biosensor technology to detecting bacteremia in real-time (i.e., less than 5 min). The premise underlying the application is that early diagnosis of bacteremia is crucial… more
Company: BRAIN RESOURCE COMPANY Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): People are living longer than ever before and one of the greatest challenges facing the elderly is maintaining adequate functional capacity as they reach advanced age. Achieving this goal in turn depends on the ability of health care providers to be able to… more
Company: EPIVAX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): EpIVax specializes in the development of epitope-driven vaccines by screening whole genomes for candidate vaccine components. In this application, we describe a rapid approach to the development of a tularemia vaccine that could be for BioDefense. First, F.… more
Company: GENESPECTRUM Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of the proposed research is to develop a method for significantly improving the performance of sequencing by hybridization (SBH), thus decreasing the cost and increasing the speed of sequencing DNA. If successful, the technology that GeneSpectrum Inc. is… more
Company: GENESPECTRUM Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): The goal of the proposed research is to develop a method for significantly improving the performance of sequencing by hybridization (SBH), thus decreasing the cost and increasing the speed of sequencing DNA. If successful, the technology that GeneSpectrum Inc. is… more
Company: KVH INDUSTRIES, INC. Agency/Program/Year/Phase: DOD / SBIR / 2004 / 2
Abstract: In Phase I, KVH Industries designed and prototyped a micro-machined all-fiber optic phase modulator and subsequently measured the modulator performance in a Sagnac interferometer gyroscope to prove feasibility of the approach. The micro-machined D fiber phase modulator is an enabling device to allow… more
Company: MARINE ACOUSTICS, INC. Agency/Program/Year/Phase: DOD / STTR / 2004 / 1
Abstract: The DARPA Phraselator is a, multilingual phrase translation system. The Phraselator is a rugged, weather resistant, voice-to-voice, translation device with superior audio input and output. It is available to both military and industrial users and more than 2,000 Phraselators have been manufactured… more
Company: PROTHERA BIOLOGICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant):
The goal of the proposed research is to demonstrate that Inter-alpha serine protease inhibitor proteins (IaIp) are an effective therapy for sepsis. In sepsis, normally high plasma levels of IaIp drop dramatically in adult and newborn patients. We hypothesize… more
Company: QUALITYMETRIC, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): Our objective is to achieve a major advance in the technology used to assess disability in children and youth. Measurement and practical requirements for identifying disability and evaluating individual progress across pediatric age groups and care settings… more
Company: QUALITYMETRIC, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): Understanding the functional impact of asthma on health-related quality of life (HRQOL) can be substantially improved using item response theory (IRT) and competing objectives of more practical and more precise assessments can be achieved over a wide range of… more
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