Abstract:DESCRIPTION (provided by applicant): A strong unmet need exists to develop new treatments for anemias associated with chronic disease states, collectively referred to as anemia of chronic inflammation (ACI). ACI is highly prevalent in the U.S. and makes alarge contribution to public morbidity and… more
Abstract:Diabetes is an epidemic disease in the United States and accounts for 15% of all US healthcare costs. The rural Mississippi Delta region is statistically at the epicenter of the negative trends in the health and has the highest prevalence of diabetes and obesity in the nation. Low health literacy… more
Abstract:Operating fossil fuel power plants at maximum efficiency requires high temperature measurements with sufficient accuracy to allow operation at optimum temperatures. Even a few degrees can reduce plant efficiency significantly. To operate with minimum downtime requires temperature measurement with… more
Abstract:ABSTRACT: There has been growing interest in nano- and micro-scale testing of materials at increasingly elevated temperatures. However technological obstacles have limited the range of materials that can be tested and limited the temperatures that can be successfully reached for experimentation… more
Abstract:This Small Business Innovation Research Phase I project will develop the technology needed for high performance neutron detectors that use Ce3+ activated 6Li glass in the form of monodisperse microspheres with strategically controlled dimensions and architecture. Current Ce3+/6Li glass scintillator… more
Abstract:Accurate Automation Corporation will develop a carbon nanotube based microstrip plasma limiter suitable for inclusion on RF printed circuit boards used on the front-end of an X-Band phased-array receiver. This device will capitalize on the ability to use carbon nanotubes to reduce the size and cost… more
Abstract:Accurate Automation Corporation (AAC) will develop a low-cost trainer based on PC technology. The objective is to provide the U.S. Navy with the ability to readily train personnel to operate unmanned vehicle systems when high-cost training systems and actual control systems are in short supply. This… more
Abstract:Accurate Automation Corporation (AAC) will deliver a Virtual Machine (VM) solution to the U.S. Army, leveraging the advantages of this technology to meet the unique needs of this information-centric, warfighting organization. AAC will consolidate an existing set of server applications, migrating the… more
Abstract:Accurate Automation Corporation proposes to develop a system design for a self-contained missile launchable RF Generator based on a frozen wave transmission line technique. The RF transmission line will be charged through an optically activated switch fabricate from silicon carbide. A high energy… more
Abstract:Accurate Automation Corporation (AAC) proposes to develop two useful software tools for the Distributed Common Ground Control Station (DCGS). These tools will help the analyst build more useful products for her customers. AAC will address opportunities for growth within the spectrum of DCGS… more
Abstract:Accurate Automation Corporation proposes to develop a high power switch with a laser trigger to minimize pulse-to-pulse jitter. The switch will incorporate carbon nanotube electrodes for long life and high current capacity. The initial design of the switch will provide switching of up to 25 kV DC.… more
Abstract:The health and integrity of aircraft sensors play a critical role in aviation safety. Unfortunately, inaccurate or false readings from these sensors can lead to improper decision-making resulting in serious and sometimes fatal consequences. The research performed in Phase I demonstrated the… more
Abstract:The primary goal of this project is to design and develop an autonomous instrumentation and control (I & C) health monitoring system for space nuclear power applications. The system, once fully developed, will be able to detect system anomalies based on analytical modeling technique using data… more
Abstract:A Light Water Reactor (LWR) is equipped with control and shutdown rods that are inserted into and withdrawn from the core to control the power level in the reactor. The positioning of the control and shutdown rods is performed via the plants rod control system, which in a typical Pressurized Water… more
Abstract:As the existing fleet of US nuclear power plants pass midlife, the aging condition of safety related systems, structures, and components (SSCs) becomes increasingly important. Electrical cables, including those used for instrumentation and control, are vital for safety related systems and problems… more
Abstract:Although nuclear power plants have provided a reliable source of power for the U.S. over the last four decades, unexpected equipment failures have resulted in losses of power production and millions of dollars of revenue, which may have been avoided if the warning signs of impending failures had… more
Abstract:Cryogenic fluid valves are subject to harsh exposure and actuators to drive these valves require robust performance and high reliability. DSM's piezoelectric actuators offer advantages over traditional alternative actuator technology. However, in order to use piezoceramic actuators in… more
Abstract:Applications for ultrasound are expanding beyond medical imaging to include new functionality, with the potential to halt internal bleeding or provide an alternative to manual suturing. These types of functions are suited to a surgical robot, offering the potential for tele-operation or even… more
Abstract:DSM demonstrated an inexpensive, non-inductive actuation mechanism that can be used in a canard actuation system (CAS) without adding noise or bias to the measurements of onboard magnetometers during guidance and fuzing operations of miniaturized precision munitions. The Piezo actuator based Phase I… more
Abstract:Dynamic Structures and Materials, LLC (DSM) proposes the design and development of a high power rotary piezoelectric driven actuator for optical assemblies for kinetic energy weapons. The proposed design uses an ultrasonic piezo ring motor to provide torque and speed. The simplicity of the design… more
Abstract:In the last decade, researchers have investigated nanofiber based medical vehicles for various biomedical applications. The challenge is to produce nanofiber vehicles outside laboratory environment for clinical trial. This proposed effort is targeted at developing a cGMP compliant prototype process… more
Abstract:DESCRIPTION (provided by applicant): One of the modern strategies for treating autoimmune diseases such as rheumatoid arthritis and psoriasis involves the use of biologic TNF receptor decoys, such as soluble receptors or therapeutic antibodies, to intercept the inflammatory ligand TNF-1, and thus… more
Abstract:History has repeatedly shown that combustion instability is the greatest technical risk faced in any chemical propulsion development program. The UCDS Process addresses this issue by using a rigorous physics-based analytical framework to decompose the complex flow field inside a chemical propulsion… more
Abstract:Microcracking issues have significantly limited the reusability of state-of-the-art (SOA) composite cryotanks. While developers have made some progress addressing this reusability issue, there are also significant reliability issues with the SOA cryotanks due to their inconsistent structural… more
Abstract:GTL has already made substantial progress in developing and validating the BHL<SUP>TM</SUP> technology for application to cryotanks. Earlier coupon testing of the temperature-dependent material properties confirmed the potential of the BHL technology to eliminate the microcracking issue… more
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