Abstract:DESCRIPTION (provided by applicant): Islet transplantation (ITx), especially with the emerging potential of xenotransplantation, holds significant promise for the treatment of type 1 diabetes (T1D). There are, however, major challenges that remain prior toits larger scale, cost-effective application… more
Abstract:DESCRIPTION (provided by applicant): Summary Overall, 36% of adult Americans, and 66% of Latinos, lack the level of health literacy needed to understand prescription drug information, such as the dosing instructions on medication container labels. Low hea
lth literacy and poor understanding of… more
Abstract:Lightweight Divert and Attitude Control Systems (DACS) can improve the mass fraction and specific impulse capabilities of propulsion systems for future MDA platforms. Proposed is the development of a novel DACS valve and actuator to provide improved capabilities for a wide range of future systems. … more
Abstract:Piezoelectric actuators constructed with the "smart material" PZT offer many potential advantages for use in NASA cryo-valve missions relative to conventional electromagnetic-driven mechanical actuators. In addition to their very high resolution (a benefit to nanopositioning applications for many… more
Abstract:Applications for ultrasound are expanding beyond medical imaging to include new functionality, with the potential to halt internal bleeding or provide an alternative to manual suturing. These types of functions are in some ways suited to a surgical robot, offering the potential for teleoperation or… more
Abstract:Dynamic Structures and Materials, LLC (DSM) proposes a novel piezoelectric ceramic motor actuator for actuating flight control surfaces such as canards in mortars and gun launched munitions. The proposed miniature piezoelectric ceramic actuation technology is based on a "inertial" vibration motor… more
Abstract:An innovate re-entry power system is proposed for development which collects the re-entry energy for a vehicle/module entering the atmosphere for LEO using an MHD power generator that is configured on the exterior surface of the vehicle nose to utilize the heated air sheath as the plasma for… more
Abstract:This Small Business Technology Transfer (STTR) Phase I project seeks to establish the feasibility of an entirely new class of liquid electrolyte separator for Li ion batteries that has a built-in reversible thermal shutdown mechanism. With increasing use of Li ion batteries, safety is of particular… more
Abstract:The UCDS process uses a rigorous theoretical model to understand the dynamics of combustion instability. In addition to predicting the amplitude of pressure oscillations, UCDS provides clear insight into why a propulsion device oscillates. To enhance and optimize UCDS for missile defense… more
Abstract:The Universal Combustion Device Stability (UCDS) Process is the culmination of more than 40 years of research and provides the means to understand the complex dynamics and processes inside any chemical propulsion system, including liquid rockets, solid rockets, hybrid rockets, turbojet combustors… more
Abstract:A recent breakthrough in combustion stability analysis (UCDS) offers the potential to predict the combustion stability of a scramjet. This capability is very important due to the extreme scramjet operational environment, which makes cut-and-try development approaches impractical. With UCDS, it will… more
Abstract:To ensure the success of mid-scale scramjet development efforts, it will be essential to include the effects of chamber pressure oscillations (i.e. instability) on the engine heat load. This will require the inclusion of both the oscillatory heat load that accompanies the pressure oscillations and… more
Abstract:Building upon the successful Phase I demonstration of the feasibility of the Blended Hybrid Laminate (BHL) technology, the Phase II effort will seek to demonstrate and validate the technology at a relevant scale. Phase II confirmation of high cryo-pressure cycle life and high structural performance… more
Abstract:History has repeatedly shown that combustion instability is the greatest technical risk faced in any rocket development program. To address this risk, Gloyer-Taylor Laboratories LLC (GTL) has created the Universal Combustion Device Stability (UCDS) process. UCDS employs a tightly integrated… more
Abstract:Military planners, humanitarian organizations, and international investors face an increasing level of uncertainty regarding geopolitical areas considered critical to their respective interests. Aside from the normal factors impacting geopolitical instability the nature and pace of climate changes… more
Abstract:In order to facilitate the discovery and synthesis of scientific information, mobile device applications and services are needed for use in the digital library by researchers and scientists to instantly locate data. During Phase I of this effort IIa will perform a requirements analysis, identifying… more
Abstract:Governmental digital libraries, such as the U.S. Department of Energy (DOE) Office of Scientific and Technical Information (OSTI) Information Bridge (IB) and Energy Citation Database, serve as the primary vehicle to make the results of the government
Abstract:DESCRIPTION (provided by applicant): Wheelchair Drive System Over half of the wheelchair user population has developed upper extremity (UE) pain and injury. One of the activities that likely contribute to the development of injury is wheelchair propulsion
. A number of technologies have been… more
Abstract:The semiconductor contacts on segmented germanium planar detectors require improvement to commercially supply better detectors at lower cost with faster delivery. In addition, this improvement will result in the utilization of significantly more high-purity germanium crystals for detector… more
Abstract:The existence of larger diameter germanium crystals will provide larger, more sensitive, gamma-ray detectors for Nuclear Physics measurements at DOE user facilities. Large Diameter germanium crystal growth techniques will be experimentally developed during the Phase I and Phase II. Large diameter… more
Abstract:DESCRIPTION (provided by applicant): The goal of this SBIR Phase I project is the development of a new drug discovery platform for screening new inhibitors of viral polymerases and for studying mechanisms of action of the prospective pharmaceutical compoun
ds. The main innovation in this project is… more
Abstract:DESCRIPTION (provided by applicant): The goal of this project is to develop a new highly sensitive and cost effective RNA Enzymatic Luminescence Assay (qELA) for high-throughput detection and quantification of microRNA in biological samples. The assay impl
ements the same detection concept known… more
Abstract:The Tai-Yang Research Company, in partnership with the Center for Advanced Power Systems at Florida State University, proposes to develop a novel solution for reducing the high heat load at the warm-to-cold electrical terminations of a high temperature superconducting cable configured for Navy ship… more
Abstract:The Tai-Yang Research Company (TYRC) proposes to address the need for high temperature superconducting (HTS) current leads used in an adiabatic
demagnetization refrigerator (ADR) for space applications, presently being developed at the NASA / Goddard Space Flight Center (GSFC). The innovation is to… more
Abstract:There is a critical need for integrated material prediction tools to assure the United States future competitiveness and national security. Extensive libraries of integrated computational tools are available for structures, heat transfer, fluid dynamics, electronics and manufacturing. These tools… more
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