Abstract:The primary objective of the proposed investigation is to develop an optimal radar altimeter waveform processor for (1) enhancing the accuracy of the altimetric oceanographic height measurements, especially near the coastal regions and ice-sheet boundaries, and for (2) autonomous and efficient… more
Abstract:The primary objective of the proposed investigation is to develop numerical tools capable of producing scalable algorithms for efficient solution of a general class of large geophysical inverse problem in a massively parallel processing (MPP) computing environment. An example problem is the rigorous… more
Abstract:We propose to build, test, and characterize a three dimensional monitor for the direct display of three (or higher) dimensional information. Our device is constructed of a three dimensional array of pixels, actually "voxels," which in their quiescent state are transparent. When these elements are… more
Abstract:WE PROPOSE TO BUILD, TEST AND CHARAXTERIZE A NOVEL THREE DIMENSIONAL MONITOR FOR THE DIRECT DISPLAY OF THREE (OR HIGHER) DIMENSIONAL INFORMATION. OUR DEVICE IS CONSTRUCTED OF A THREE DIMENSIONAL ARRAY OF PIXELS, ACTUALLY "VOXELS", WHICH IN THEIR QUIESCENT STATE ARE TRANSPARENT. WHEN THESE ELEMENTS… more
Abstract:THE RESEARCH EXAMINES THE DESIGN OF PEAK STRAIN AND DEFLECTION-BASED INSTRUMENTATION SYSTEMS FOR THE POST-EARTHQUAKE HEALTH MONITORING OF BUILDINGS AND OTHER STRUCTURES. THE INSTRUMENTATION SYSTEMS ARE INTENDED TO EVALUATE THE LOCAL MATERIAL DAMAGE AT SPECIFIC POINTS WITHIN A STRUCTURE, AND USED TO… more
Abstract:Road condition monitoring is a stated objective of TRP 93-025. Bridge safety is a major component of the nation's road infrastructure and is therefore of particular interest to the USDOT and the IVHS program. The Georgia DOE has agreed to participate with Strain Monitor Systems, Inc. to accomplish… more
Abstract:AVAILABLE NDT TECHNIQUES CAN DETECT RELATIVELY LARGE DEFECTS IN DRILLED SHAFTS. TO PROVIDE INFORMATION ABOUT THE SIZE OR SHAPE OF THE DEFECT, SOME TECHNIQUES REQUIRE EMBEDDING SENSORS INSIDE OF HAVING ACCESS ALONG THE LENGTH OF THE SHAFTS. SUCH REQUIREMENTS LIMIT THEIR APPLICABILITY TO NEWLY… more
Abstract:SYSTEMS & PROCESSES ENGINEERING CORPORATION (SPEC) HAS DEVELOPED A DIGSYSTEMS & PROCESSES ENGINEERING CORPORATION (SPEC) HAS DEVELOPED A DIGITAL GAIN CONTROLLED INSTRUMENTATION AMPLIFIER ASIC SYSTEM DESIGN FOR ITAL GAIN CONTROLLED INSTRUMENTATION AMPLIFIER ASIC SYSTEM DESIGN FOR INTERFACING A… more
Abstract:Systems & Processes Engineering Corporation (SPEC) proposes to develop a high speed data acquisition module using state-of-the-art GaAs integrated circuit and Multi-Chip Module (MCM) technologies. The data acquisition MCM will include an 8-bit ADC, a custom GaAs integrated circuit, 32 Kbytes of RAM,… more
Abstract:Systems & Processes Engineering Corp. (SPEC) has developed a Phase Resolved Fluorescence Spectroscopy (PRFS) biosensor which is capable of detecting and classifying biological materials. SPEC's PRFS biosensor uses lifetime fluorescence to provide: (1) enhanced senstivity to structural differences… more
Abstract:Systems & Processes Engineering (SPEC), together with the COMSAT Laboratories, proposes to develop FPSS as dual use technology to support a flyable fast packet switch communications package applicable to a small, low cost commercial or military satellite. Such a flight demonstration would support… more
Abstract:Passive immunization with broadly neutralizing antibodies is a promising approach for preventionand treatment of HIV-1 infection. We have generated an HIV-1 neutralizing human antibody which bindsto the principal neutralizing determinant (PND) of the envelope glycoprotein gp12O. The antibody… more
Abstract:Development is proposed for a breakthrough technique involving the use of electro-magnetic radiation to detect and measure thickness of non-conductive coatings on both metallic and non-metallic surfaces. The primary objective of the Phase I effort will be to prove that this approach can detect all… more
Abstract:A significant problem in precision manufacturing of large parts/assemblies is the requirement to make measurements over the surfacesof these parts for a variety of reasons including inspection/quality control; control of surfacing operations such as coatings, abrasive erosion, buffing, and… more
Abstract:The research objective is synthesis of a conjugate of mitomycin C to an antisense phosphorothio-ate nucleotide targeted to proliferating smooth muscle cells responsible for arterial occlusion. This wouldprovide a novel approach to the prevention of restenosis, for which there is currently no… more
Abstract:This study will develop a new anti-thrombotic drugs for the treatment of thromboembolicdisorders. In pilot studies, a coagulation inhibitor has been identified in an aqueous extract of Anodontiawoodiana. Early chromatographic and spectral data suggest that the active principle(s) may be a… more
Abstract:Effective therapy for human immunodeficiency virus (HIV) infection remains elusive, partly dueto the fact that infected long lived cells provide a reservoir for the virus. Currently availableanti-retroviral agents are reverse transcriptase inhibitors. In spite of their success, these compoundshave… more
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