Abstract:Cross contamination between patients, medical personnel and home care givers can be a serious problnursing care. Whenever the integrity of the skin barrier is broken by surgical procedures, irritatiocommon skin bacteria may cause infections. Infection may be reduced by washing the skin with a… more
Abstract:SYSTEMS & PROCESSES ENGINEERING CORPORATION (SPEC) IS PROPOSING TO DEVELOP A DEEP STRIKE SECURITY EXPERT PLANNER (DSSEP). DSSEP IS A HIGH PERFORMANCE EXPERT SYSTEM DECISION AID THAT ASSISTS COMMANDERS TO PLAN FOR THE SECURITY OF U.S. ARMY MANEUVER ELEMENTS, PROVIDING INCREASED ECONOMY OF FORCE AND… more
Abstract:System & Processes Engineering Corporation (SPEC) proposes to develop a high speed,high density solid state flight data recorder using state-of-the-art CMOS integrated circuit and Multi-Chip-Module (MCM) technologies. the solid state recorder will include 2 MEG x 8 synchronous dynamic random access… more
Abstract:Systems and Processes Engineering Corporation (SPEC) proposes to develop a chip set to digitize, compress, encrypt, encode, and modulate fast motion video and focal plane array waveforms. The ASIC chip-set will be integrated into a Multi-Chip Module (MCM) and will be compatible with existing… more
Abstract:Conventional fiber optic fluorosensors absorb and re-emit in the UV/VIS spectral range. The unavailability of UV/VIS light sources makes these fluorosensors prohibitively costly and unreliable. Systems & Processes Engineering Corporation (SPEC) proposes to develop an embedded fiber optic… more
Abstract:Systems & Processes Engineering Corp. (SPEC) proposes to develop a compact, low-cost multi-analyte immunomagnetic biosensor system for rapid, selective, and sensitive detection and identification of several individual viruses and toxins simultaneously in a biotoxoid mixture. The proposed biosensing… more
Abstract:The US Army is continually faced with the task of providing the crew members of weapon systems with realistic, high-quality training. This training must be based on known principles of instructional design, yet meet the needs of specific weapon system based training issues. The problem of providing… more
Abstract:The crew of direct fire weapon systems in an active fire fight are subject to information overload and conflicting priorities, particularly in a target-rich environment. Such parameters as distance to target, immediacy of threat, target value assessment (TVA), lethality against a specific target… more
Abstract:RESEARCHERS ARE EXPLORING NEW TECHNOLOGY THAT CAN BE USED TO DEVELOP A LOW-COST MODULAR NMR CONSOLE THAT CAN REPLACE ANY COMMERCIALLY AVAILABLE CONSOLE AND PROVIDE UP-TO-DATE PERFORMANCE AT A COST OF LESS THAN $100,000. RF TECHNOLOGY CURRENTLY USED IN CELLULAR PHONE AND OTHER CONSUMER PRODUCT… more
Abstract:This proposal discusses the need for a monitor on commercial aircraft capable of detecting RF emissions over a broad dynamic range and an extremely wide electromagnetic spectrum. The security monitor has two purposes: (1) detect inadvertent RF emissions from passenger's portable electronic devices… more
Abstract:Bumper systems having lower cost and high performance are the goal of this research effort. To achieve this goal the use of recycled materials and advanced processing techniques will be investigated. These bumper systems will serve to protect the structural integrity of ships, piers, and offshore… more
Abstract:Elastomeric O-rings provide a critical sealing funcion in a myriad of devices of military and commerical interest. A critical problem with currently available O-rings occurs when the O-ring material stiffens at low temperatures, causing a failure in sealing. Previous work by the Army has indicated… more
Abstract:Phased array designs for microwave and communication applications incorporate large numbers of transmit/receive (T/R) modules. High part counts lead to concern about T/R module reliability and improvements in semiconductor device manufacturing techniques and materials technology make lifetime… more
Abstract:The use of lead projectile cores in current U.S. Army small caliber ammunition has caused increasing concern over the environmental contamination of military firing ranges and surrounding areas. A number of military firing ranges are in danger of being closed due to high levels of lead… more
Abstract:Sudden, catastrophic fatigue failures in 40 to 50 year old Navy cranes pose a significant danger to personnel and facilities. These aging cranes are currently used to lift nuclear materials and other sensitive payloads. Nondestructive Evaluation (NDE) methods of fatigue crack analysis are… more
Abstract:AIDS is a fatal disorder of the immune system caused by the HIV and is a widespread epidemic. The lobjective of this work is to treat human AIDS patients with a novel oligonucleotide (T30177) that haanti-HIV activity. We will perform preclinical animal pharmacology studies, including… more
Abstract:Cytomegalovirus (CMV) causes severe infections in infants, organ transplant recipients and AIDS patlong term objective of this work is to treat humans who have cytomegalovirus infections with a novelspecific aims of this grant are to perform animal pharmacology studies, including efficacy,… more
Abstract:We will develop a new class of oligonucleotides, which fold themselves into ordered structures andmainly of deoxyguanosine and deoxythymidine (GTOs), as therapeutic antiviral agents active against HGTOs as antiviral agents represents the results of a productive investigation into the mechanism… more
Abstract:We will develop certain structure activity relationships with respect to a novel class of antiviralconduct preliminary experiments designed to define the mechanism of action for these drugs. Preliminestablished that certain alkenes, when attached to a guanine congener, provide potential antiviral… more
Abstract:Antisense and triple helix-forming oligonucleotides (TFOs) have great potential as therapeutic agenspecifically block the expression of deleterious genes. We will develop novel delivery vehicles, tointernalization and membrane permeability of oligonucleotides. These compounds are polyaminolipids… more
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