Abstract:DESCRIPTION (provided by applicant): Capnometers can fail in a number of ways that are not detectable using current static calibration testing procedures. These failures could include leaks in the sample line, a weak sample pump, inadequate dynamic response, flow restriction and flow obstruction.… more
Abstract:To support NASA's vital interest in developing much larger solar array structures over the next 20 years, MotionPort LLC's Phase I SBIR project will strengthen validated modeling analysis and simulation techniques by developing a vertical application to simulate the nonlinear dynamics of… more
Abstract:DESCRIPTION (provided by applicant): Human African trypanosomiasis (HAT) is an infectious disease with a large global health burden occurring primarily in Central and Eastern Africa. HAT is 100% fatal if untreated and the current drug therapies suffer frompoor safety profiles, difficult treatment… more
Abstract:Project Summary Evasion of apoptosis is a hallmark of cancer and is associated with oncogenesis, tumor maintenance, and resistance to conventional chemotherapy. BCL-2 was the first identified anti-apoptotic factor and is a member of the BCL-2 family of proteins that cooperate in the regulation of… more
Abstract:Agricultural sorting and grading is most commonly preformed primarily through the use of human resources. Farm workers sort crops by hand through visual inspection. This process is expensive and highly subjective. In addition the labor force is susceptible to human error which can impact the quality… more
Abstract:The US Department of Energy has a stated goal to increase the energy efficiency of turbines, and one well recognized method of achieving this is through the use of ceramic thermal barrier coatings (TBCs). However, state of the art zirconia-based TBCs have a temperature limit of about 1200oC, and new… more
Abstract:In this SBIR Project MagiCom proposes several innovative concepts to develop a light weight and low power communication system to enable small kill vehicle communications in flight. The proposed Communications Concept will have the lowest possible weight impact on the KV. MagiCom proposes an… more
Abstract:This proposal describes an innovation for making bulk nanocrystalline tungsten alloys that will be sufficiently ductile and meet mechanical properties targets set by the army. Tungsten (W) and its alloys are primary candidate materials for next generation munitions and warheads owing to its high… more
Abstract:DESCRIPTION (provided by applicant): The aim of this innovative proposal is to commercialize a non-invasive topical product that treats uveitis which is safe and easy to administer. Uveitis is the third leading cause of blindness in the United States. Heretofore, the primary treatment of… more
Abstract:ABSTRACT: Recent SES full-scale testing of composite Instrument Landing System Glide Slope (ILS/GS) Towers indicates that frangibility for these large NAVAID structures is indeed possible. However, there is currently no clear and definitive definition of frangibility (with respect to force and… more
Abstract:The United States is currently faced with unprecedented energy challenge. Petroleum prices have skyrocketed due to rising competition for energy resources from emerging economies. There is a significant need for processes that can produce hydrocarbons from renewable resources rather than petroleum.… more
Abstract:This Small Business Innovation Research Phase II project will demonstrate techno-economic feasibility of a novel bioprocess to produce fatty acids from lignocellulosic biomass leading to commercialization. These fatty acids are primary components of several consumer products such as skincare,… more
Abstract:The proposed contract effort is for the design, development and proof-of-concept demontration testing of a low cost, pressure-fed liquid rocket booster propulsion system concept. The contract focus will be on four key component technologies in the booster system; (1)composite propellant tanks,… more
Abstract:High Performance Computing has enabled computer modeling of everlarger and more complex problems. For some of these problems, models utilizing allhexahedral meshes are preferred due to better accuracy and efficiency. However, algorithms for automatic generation of all hex meshes in general… more
Abstract:In response to this U.S. Department of Energy Phase I Energy Conservation Applications for Solid- State Lighting (OLEDs) SBIR, InnoSys and Universal Display Corporation (UDC) propose to develop and commercialize drivers and power supplies specifically designed for high efficiency phosphorescent… more
Abstract:The development of large-area (m2) photodetectors with time resolutions of picoseconds (10-12 seconds) and submillimeter space resolutions would open new opportunities in many areas, including collider detectors, rare kaon experiments, and neutrino experiments in particle and nuclear physics, X-ray… more
Abstract:The need for wire that is able to be heated up to high temperatures span a very large and diverse number applications and fields of use from everday consumer applications to advanced military and industrial applications. Some of these applications require heater wire that operate at very high… more
Abstract:ABSTRACT: The Air Force has identified a need for efficient, lightweight, millimeter-wave transmitter development that supports future generations of bandwidth efficient military satellite communications and communications links between Remotely Piloted Aircrafts (RPAs), satellites and terrestrial… more
Abstract:ABSTRACT: Advanced wide bandgap (WBG) solid state technology is necessary for future military, defense and related Department of Defense (DoD) applications and needs with increased power demand and higher temperature operation ranges. To make further advancements, an enabling high temperature and… more
Abstract:It is desirable for the standard Intersystem EMC electromagnetic environments that aircraft must operate in and demonstrate survivability of prior to production and deployment to be a single environment that provides both peak and average field level tests at the same time (instead of splitting the… more
Abstract:DESCRIPTION (provided by applicant): Chronic gingival inflammation of the soft tissue surrounding the tooth afflicts over half of all American adults. In the most severely affected, progression of this inflammatory process to the deeper periodontal ligaments and alveolar bone results in tooth loss… more
Abstract:ABSTRACT: Ground Surveillance Radar (GSR) is a fundamental and proven component of Department of Defense"s (DoD) Battlefield Awareness. Advanced radar systems on large remotely piloted aircraft (RPAs) include Synthetic Aperture Radar (SAR) and Ground Moving Target Indicators (GMTI). The… more
Abstract:DESCRIPTION (provided by applicant): Rheumatoid arthritis (RA) affects approximately 1.3 million adults in the United States and up to 1.5% of the population worldwide. In its progressive form the disease has debilitating effects including painful inflammation and destruction of the joints. This… more
Abstract:DESCRIPTION (provided by applicant): Age-Related Macular Degeneration is the most common cause of legal blindness in people over 60, affecting an estimated 1.6 million patients. Additionally, over 400,000 diabetic Americans are diagnosed each year with vision-threatening retinal edema and/or… more
Abstract:DESCRIPTION (provided by applicant): With 33 million people living with HIV/AIDS (including 1.2 million in the US), and 1.8 million AIDS-related deaths annually, HIV/AIDS remains a formidable global epidemic (UNAIDS, CDC). Modern HIV therapy combines drugsfrom different classes to form cocktail … more
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