Abstract:DESCRIPTION (provided by applicant): In the last two decades though the field of neuroprosthetics has gained tremendous momentum through the development of novel architectures for neural interfaces, however, till date there is no device which can be nomenclatured as the gold standard in the field.… more
Abstract:DESCRIPTION (provided by applicant): In order to successfully use microelectrode arrays for stimulation in chronic implantation, the neural electrode must have longevity and efficacy. Efficacy of stimulation primarily means injecting enough charge to the targeted tissue to elicit action potentials.… more
Abstract:This Small Business Technology Transfer (STTR) Phase I Project aims to optimize and test prototypes of continuous, multi-analyte sensors based on stimuli-responsive hydrogels. The proposed sensor array will be capable of monitoring multiple biomarkers relevant to several common human diseases such… more
Abstract:Espira has developed a Biohazard Water Analyzer (BWA) for field-based rapid pathogen detection. BWA employs advanced technologies including microfluidic sample preparation for nucleotide analysis and highly sensitive carbon nanotube-based electrochemical sensing for rapid detection of indicator… more
Abstract:Existing building stock represents a significant opportunity for energy savings through efficiency measures, as it accounts for 41% of US energy use. Advanced control strategies and better systems commissioning offer the least expensive routes to energy savings by utilizing existing building… more
Abstract:Critical to determining the success of an EGS well is the measurement of the flow distribution along the open-hole length of that well. Knowledge of not only the depth but the spacing of intersected fractures is required in order to determine the sweep efficiency of fluids flowing through the… more
Abstract:DESCRIPTION (provided by APPLICANT): Medical errors are recognized as the cause of numerous deaths, and even if some are difficult to avoid, many are preventable. Computerized physician order-entry systems with decision support have been proposed to reducethis risk of medication errors, but these… more
Abstract:DESCRIPTION (provided by applicant): Accurate measurement of core body temperature during surgery as well as in critical care is imperative to a positive outcome and ongoing quality of life for patients. Core temperature management of patients during extended anesthesia such as cardio-pulmonary… more
Abstract:NASA has numerous missions that involve radar and radiometry. In the past, the practice has been to build each system as a one-off program, which makes MMIC design unattractive from a cost perspective. In an era of reduced budgets and the need for higher efficiencies both in R & D cost reduction… more
Abstract:The synthesis of ammonia through nitrogen fixation is a vital component to all plant life and the world economy as a fertilizer and commodity chemical. The global industial production of ammonia exceeded 140MM tons in 2009 and is expected to grow to 160MM tons by 2020. Most ammonia,>90% is… more
Abstract:This Small Business Technology Transfer (STTR) Phase I project is to develop an inexpensive and rapid sensing technology for detection of tuberculosis (TB) at the point of care (POC). Rapid screening of TB in rural areas is difficult because current diagnostic methods are expensive, time consuming… more
Abstract:DESCRIPTION (provided by applicant): Schizophrenia is a complex psychiatric disorder with a heterogeneous clinical phenotype. It is probably one of the most costly psychiatric illnesses, yet the development of novel and safe antipsychotics lags behind. Amplifying the actions of endocannabinoids by… more
Abstract:DESCRIPTION (provided by applicant): Despite notable achievements over the past two decades, cancer remains a challenging 21st century epidemic demanding new, more effective drugs. Nitric oxide (NO) is well known to kill cancer cells without harming normal bone marrow cells, but until now has not… more
Abstract:The US Department of Energy has a stated goal to increase the energy efficiency of turbines, and one well recognized method of achieving this is through the use of ceramic thermal barrier coatings (TBCs). However, state of the art zirconia-based TBCs have a temperature limit of about 1200oC, and new… more
Abstract:The proposed research will look at a combination of low-cost radar, stereo camera, and lidar data to generate a 3D model of the terrain ahead of a vehicle. The resulting terrain model will be automatically segmented, simplified and compressed to produce a reasonable description, which can interact… more
Abstract:Environmental Benefits: The proposed technology relates to Climate change and sustainable energy. Fatty acids are currently produced from palm oil, 80% of which comes from Malaysia and Indonesia. Both these countries have finite land available and often times rainforests are destroyed to make way… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project aims to further develop ATX-Red, an in vivo imaging agent that becomes fluorescent in the presence of the enzyme autotaxin. Autotaxin and its product LPA are involved in numerous biological functions that generally involve cell movement… more
Abstract:There needs to better biomarkers of alcohol consumption and alcohol induced organ damage. PEth is a nonoxidative, long-lasting metabolite of ethanol consumption and alcohol related organ damage. PEth may also play a role in cell and organ damage. In this contract antibodies are made to PEth for… more
Abstract:ABSTRACT: The Air Force has identified a need for efficient, lightweight, millimeter-wave transmitter development that supports future generations of bandwidth efficient military satellite communications and communications links between Remotely Piloted Aircrafts (RPAs), satellites and terrestrial… more
Abstract:Todays warfighter and NETT Warrior are reliant on small battery operated devices for communication, information systems, enemy detection, and battlefield management. These devices must be recharged on a regular basis to ensure sustained operation. Current charging technologies require the device to… more
Abstract:ABSTRACT: ImSAR LLC and Solid State Scientific Corporation (SSSC) propose to leverage ImSAR's proven radar hardware and ground processing capabilities along with SSSC's expertise in radar signal processing, SAR-based GMTI, and automatic/assisted target recognition to advance the state of… more
Abstract:To reduce oxidative stress of patients with sickle cell anemia, the solicitation calls for harvesting hemoglobin-binding haptoglobin from the donated blood and intravenously injecting haptoglobin to the patient to capture and process free sickle cell hemoglobin in the blood. Polymorphic haptoglobins… more
Abstract:DESCRIPTION (provided by applicant): The goal of this translational SBIR program is to create a small, implantable system for recording myoelectric signals from residual and reinnervated muscles of individuals with forearm and other amputations. The signals will be wirelessly coupled to an external… more
Abstract:The use of Spread Spectrum Time Domain Reflectometry (SSTDR) that has already been proven in aerospace applications will be adapted and optimized for detection and location of wiring faults in shipboard systems. SSTDR is the only technology that allows MCS fault detection and isolation, on fully… more
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