Abstract:The availability of ultraclean (near-zero emission), abundant, low-cost domestic energy is critical to providing economicprosperity, strengthening energy independence, and enhancing environmental quality. To accomplish this, it is required to develop a new generation of clean fossil fuel based power… more
Abstract:HemoSonics LLC is developing an easy to use and easy to interpret diagnostic device to rapidly identify diffuse coagulopathies in order to guide proper and evidence-based interventions. The management of diffuse coagulopathies is extremely important in military medicine as these conditions represent… more
Abstract:DESCRIPTION (provided by applicant): The Problem: Venous thromboembolism (VTE), which encompasses the diseases of deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common and life-threatening problem amongst cancer patients. In population-basedstudies, cancer has been associated with a… more
Abstract:DESCRIPTION (provided by applicant): The monitoring and management of the hemostatic balance in neonatal and pediatric patients remains challenging. Although several conditions/procedures are known to have great impact in altering hemostatic function in this population, the differences between … more
Abstract:Our military"s ability to dominate the battlespace depends on the ability to first"see"the battlespacethat is, for our military commanders to have awareness of the environment, entities, activities, and intent of both our adversaries and ourselves. The things we don"t control… more
Abstract:The trend toward storage of data collected by the U.S. military and Intelligence Community (IC) in high performance computing facilities (i.e.,"data clouds") enables historical retrospective comparison of data to new collections to facilitate pattern discovery for prediction. However, many… more
Abstract:ABSTRACT: We propose to design OPTIMUS, Optimized Planning Through Iterative Mission Updates and Synthesis, a Command and Control system to provide the capability of continuous Operation Plan (OPLAN) update for use by the Joint Task Force Air Component Commander and in an Air Operations Center… more
Abstract:Harmonia is proposing to develop the Information Technology Analytical Maintenance and MOnitoring (IT-AMMO) system, a software application for Condition Based Maintenance (CBM) and Distance Support (DS) for IT systems aboard LCS ships. IT-AMMO will help the LCS Program monitor health and status… more
Abstract:From Harmonia"s long experience on human factors, console design, and usability engineering we learned that we could bring about better HSI design if we could utilize a validated model and associated computer-based tool. Our proposed tool, ImpactModeler, fuses the many factors and data sources… more
Abstract:COAXIS (Course of Action Extra-Intelligence System) recommends both information relevant to an operational order and a course of action (COA), where COA is defined as a decision of what action to take given a specific situation. COAXIS performs semantic analysis of natural language of an operational… more
Abstract:ABSTRACT: The objective of this sequential Phase II SBIR is to deliver a Technology Readiness Level 6 (TRL-6) airborne HF, VHF and UHF RF direction finding system that is suitable for integration with SUAS and to demonstrate it in a realistic airborne environment against representative signals. … more
Abstract:Ballistic and blast protection of both the crew and vital equipment onboard U.S. Navy surface ships and carriers is a critical component in the design of topside structures on these vessels. Materials such as glass, Plexiglas and polyurea are being considered and implemented for protection in these… more
Abstract:Recent events such as the fire on the USS GEORGE WASHINGTON have shown that communications and decision making can have a dominant impact on scenario outcomes involving shipboard fires. The processes by which information is learned, disseminated, assembled, and processed have a direct effect on… more
Abstract:Deployment of unmanned systems continues to expand across a wide range of missions; for example, logistics and resupply missions, force application and protection, and improving battlespace awareness. Presently these unmanned systems run at the lowest of four possible levels of autonomy, that is,… more
Abstract:DESCRIPTION (provided by applicant): R43 SBIR: Development of an iPSC-derived human vascular system for drug development. ABSTRACT Human inducible pluripotent stem cells (iPSCs) can be differentiated into vascular endothelial (iEC) and smooth muscle (iSMC)cells and hold immense potential for… more
Abstract:DESCRIPTION (provided by applicant): Human inducible pluripotent stem cells (iPSCs) proliferate readily and can be terminally differentiated into hepatocytes, which potentially makes them an attractive, cost-effective resource compared to primary human hepatocytes. Moreover, the ability to… more
Abstract:The use of advanced ceramic materials, such as silicon carbide, for light water reactor fuel cladding is being investigated, in part due to the increased safety margin afforded by this technology over conventional zircaloy metallic claddings. In light of the Fukushima events, safety concerns have… more
Abstract:A development program is proposed for a design automation software package that enables the generation of complex surfaces, with user defined or automated definition of point charge and hydrophobic/hydrophilic properties, using DNA origami as a presentation substrate. Building upon Parabon"s… more
Abstract:The recent use of organophosphate (OP) nerve agents against combatants and civilians in Syria has validated the importance of developing new drugs and biologics that sequester and catalytically degrade organophosphate (OP) nerve agents in the body before they cause morbidity and mortality. We… more
Abstract:The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project is the development of a screening method to reliably identify binding agents that can be used to target drugs to specific tissues or cell types. Targeting drugs can increase their effectiveness and… more
Abstract:3 Phoenix, Inc. proposes to develop and evaluate technology that provides a substantial improvement in processing capability for autonomous sonar processing. Improved signal processing, automated classification and propagation models place additional loads on battery power. 3Pi proposes to… more
Abstract:The operational need for this improved towed array technology insertion initiative stems from the necessity to improve availability and reliability of towed arrays in use on submarines in both shallow and deep water environments, and represents a critical submarine capability enhancement. The… more
Abstract:Adaptive Methods, teamed with Navmar Applied Sciences Corporation (NASC), proposes to develop algorithms for a Tactical Decision Aid (TDA) capable of adaptively tracking and predicting the locations of drifting mines. The TDA is capable of optimizing Mine Counter Measure (MCM) asset deployment plans… more
Abstract:This proposal addresses the challenges presented by multiple systems currently fielded onboard various Navy platforms containing incoherent USW C2 capabilities. These systems include CV-TSC, USW-DSS, SQQ-89/CADRT, GCCS-M, CFn and SWFTS. The redundant and overlapping capabilities, amplified by less… more
Abstract:This proposal addresses the challenges presented by multiple tactical pictures being fielded via various Navy systems that attempt to provide a"Common Tactical Picture"(CTP). These systems include CV-TSC, USW-DSS, SQQ-89/CADRT, GCCS-M, AEGIS, SSDS, CFn and SWFTS. These redundant and… more
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