Abstract:Beta thalassemia, the most common disease inherited at a single genetic locus, is a major cause of morbidity and mortality in populations having high frequencies of the beta-thalassemia mutations. At this juncture, the mainstays of therapy in afflicted populations consist of population screening,… more
Abstract:THE PROPOSED RESEARCH ASKS HOW DECISION MAKING CAN BE SUPPORTED AND IMPROVED IN THE AUTOMATIC TARGET RECOGNITION ENVIRONMENT, IN THE LIGHT OF (A) BIASES IN HUMAN DECISION BEHAVIOR AND (B) NATURAL HUMAN REPRESENTATIONAL AND REASONING STRATEGIES. WE WILL (1) STUDY ATR DETECTION, IDENTIFICATION,… more
Abstract:This effort would develop the laboratory set-up of the solderability tester into a real time statistical process control tool in the manufacture of printed wiring boards. By correlation of SERA test data to copper contamination levels in the solder plating bath; and the application of statistical… more
Abstract:The objective is to determine how two artificial intelligence technologies (intelligent data discovery and neural networks) can be used to provide predictions of a chemical's potential toxicity and carcinogenicity through biological data from short-term tests. The project team expects to find that… more
Abstract:IN SUPPORT OF THE REDEFINED "NON-LINEAR BATTLEFIELD" AND AIRLAND BATTLE STRATEGY, THE ARMY'S NEW COMMAND AND CONTROL DOCTRINE EMPHASIZES A MAJOR SHIFT IN TECHNOLOGICAL NEEDS FOR THE SERVICE WITH GREATLY INCREASED EMPHASIS ON INTELLIGENCE FOR AN INTEGRATED PICTURE OF THE BATTLEFIELD. UNDERLYING THIS… more
Abstract:MANY CURRENT AND PLANNED DEFENSE AEROSPACE PROGRAMS DEPEND CRITICALLY UPON RAPID DEVELOPMENT OF LIGHTWEIGHT COMPOSITE MATERIALS HAVING UNPRECEDENTED HIGH-TEMPERATURE PROPERTIES. CONTINUOUS FIBER REINFORCED INTERMETALLIC MATRIX COMPOSITES (IMC'S) HAVE THE POTENTIAL TO MEET THESE PERFORMANCE… more
Abstract:Advanced turbine engines and flight vehicles will depend upon new, high-temperature metal matrix composites (MMC's) to meet performance goals. Engineering characterization of such materials is difficult and costly, which accounts for the meager property database available to designers. Thin-walled… more
Abstract:We will develop transgenic tobacco as a cost-effective bioproduction system for human glcocerebrosidase (hGCase). Enzyme replacement using hGCase is the most effective current therapy for Gaucher disease, but its supply from human placenta is limited and its cost per patient is prohibitive.… more
Abstract:DCS WILL CONDUCT A STRUCTURED AND SYSTEMATIC RESEARCH PROGRAM INTO NEAR AND MID-TERM OBSTACLE AND TERRAIN AVOIDANCE TECHNOLOGIES. THE GOAL WILL BE TO IDENTIFY THE MOST PROMISING SENSOR TECHNOLOGIES AND CONFIGURATIONS FOR FURTHER DEVELOPMENT AND INCORPORATION INTO ARMY HELICOPTERS. THIS WILL BE… more
Abstract:Aerosol sprays of paint, epoxy, and other substances can be dispensed by mines and other munitions to disable hostile sensors, vehicles, and weapon systesm. For example, a paint-filled aerosol mine could be designed to detect an approaching vehicle, pop into the air, and eject and aerosol mist of… more
Abstract:DSA proposes to develop a cost benefit analysis tool for command, control, communications, and computer (C4) systems. This tool will incorporate the best combination of methods from the fields of economic analysis, decision analysis, and optimization into a comprehensive functional/economic… more
Abstract:This research is aimed at producing a dependable system design prototype. It will serve as a testbed for research on the integration of dependability automation suport into the systems design process by assisting designers in quantifying tradeoffs between dependability and other system attributes.… more
Abstract:Decision Science Associates, Inc. (DSA) proposed to develop and demonstrate an automated decision support tool for long-range acquisition planning. This tool will support the assessment and prioritization of system concept alternatives and supporting technologies based on military operational… more
Abstract:Adolescents make health, lifestyle and other decisions which can affect them and others over their entire lives. Research has found them often to be seriously misguided. A method exists to counter decision making deficiencies-personalized decision analysis (PDA)-but its acceptance outside a circle… more
Abstract:It is proposed to develop a mathematical model for the bistatic signature of chaff, as well as weather (rain and fog). The model will include the full scattering matrix and temporal and spatial amplitude and phase fluctuation statistics. The model will be parametric in such factors as the electrical… more
Abstract:WE WILL ADAPT AND IMPROVE AN INNOVATIVE MOVING-TARGET DETECTION AND TRACKING APPROACH, BASED ON ARTIFICIAL NEURAL NETWORK (ANN) PROCESSING TECHNIQUES, FOR APPLICATION TO THE TRACKING OF BOOST-PHASE MISSILE TARGETS IN THE PRESENCE OF INFRARED CLUTTER DUE TO HIGH-ALTITUDE NUCLEAR EXPLOSIONS (BANES).… more
Abstract:VERY FEW ORAL ENGLISH PROFICIENCY ASSESSMENT INSTRUMENTS EXIST THAT ARE APPROPRIATE FOR LIMITED-ENGLISH-PROFICIENT (LEP) ADULTS IN VOCATIONAL EDUCATION AND EMPLOYMENT TRAINING PROGRAMS. THE AVAILABLE INSTRUMENTS REQUIRE LEVELS OF STUDENT AND STAFF TIME AND OTHER PROGRAM RESOURCES THAT ARE DIFFICULT… more
Abstract:REQUIREMENTS FOR HIGHER THROUGHPUT CAPABILITIES DRIVE SYSTEM DESIGNERS TO SPECIAL PURPOSE COMPUTERS, OR PROCESSORS. THESE ARE OFTEN COMBINATIONS OF MODULAR PROCESSING RESOURCES, MEMORY, CONTROL, AND I/O.AS THE NUMBER AND CAPABILITY OF THESE REQUIRED TO SOLVE EACH PROBLEMGROWS, THE ARCHITECTURE, OR… more
Abstract:PROCESSING REQUIREMENTS FOR NEXT GENERATION SONAR SYSTEMS WILL REQUIRE THE USE OF THE AN/UYS-2. THIS NEW GENERATION STANDARD SIGNAL PROCESSOR IS A PARALLEL DISTRIBUTED PROCESSING SYSTEM THAT IS BASED ON ASTATE-OF-THE-ART DATA FLOW METHODOLOGY USING NEW LANGUAGES SUCH AS ADA, THE PROCESSING GRAPH… more
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