Abstract:OPTICS USED IN SENSORS OR MISSILE SYSTEMS ARE MADE FROM SAPPHIRE, OR SILICON CARBIDE BECAUSE OF THEIR EXCELLENT OPTICAL OR INSULATING PROPERTIES, THEIR INERT, AND THEIR ABILITY TO RESIST HARSH ENVIRONMENTS. POLISHING SAPPHIRE BY MECHANICAL OR MECHANOCHEMICAL METHODS INDUCES RESIDUAL DAMAGE AND… more
Abstract:The frequency and severity of medical malpractice claims, and the resultant cost to the health care system, has been increasing steadily since the l97Os. Research has revealed that poor communication between health care providers and health care consumers is a significant cause of the crisis. This… more
Abstract:THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP AND BUILD A HARDWARE PROTOTYPE OF AN ELECTRONIC SAFE AND ARM (ESA) FOR HIGH VELOCITY/ ACCELERATION PROJECTILES. THE HARDWARE PROTOTYPE SYSTEM WILL DEMONSTRATE THE DESIGN FOR THE HIGH VOLTAGE CONVERTER, TRIGGER CIRCUIT AND INTERFACE TO A SLAPPER DETONATOR… more
Abstract:WE PLAN TO EXPLOIT THE ISOLATION OF A CELL LINE FROM ERYTHROLEUKEMIC MURINE TUMORS WHICH IS HIGHLY SENSITIVE LINE FROM ERYTHROLEUKEMIC MURINE TUMORS WHICH IS HIGHLY SENSITIVE TO ERYTHROPOIETIN. WE WILL UTILIZE THIS LINE TO DEVELOP A SENSITIVE AND SPECIFIC BIOASSAY FOR ERYTHROPOIETIN IN HUMAN SERUM.… more
Abstract:FETAL HEMOGLOBIN CAN GREATLY REDUCE THE SYMPTONS OF HEMOGLOBIN DISORDERS SUCH AS SICKLE CELL AMEMIA AND B-THALASSEMIA DISEASES WHICH AFFECT MILLIONS OF PEOPLE WORLDWIDE. CYTOTOXIC AGENTS ARE CURRENTLY BEING USED TO ATTEMPT TO SWITCH THE ADULT PROGRAM OF HEMOGLOBIN SYNTEHSIS TO FETAL HEMOGLOBIN IN… more
Abstract:Approximately half of the individuals diagnosed with cancer will die of the disease even if the receive the best therapies that modern medicine has to offer. In addition, even with current therapies, including surgery, radiation, and chemotherapy induced remission, the side effects are ravaging and… more
Abstract:Approximately half of the individuals diagnosed with cancer will die of the disease even if they receive the best therapies that modern medicine has to offer. In addition, even with current therapies, including surgery, radiation, and chemotherapy induced remission, the side effects are ravaging and… more
Abstract:Human bone marrow can be transplanted into sheep fetuses when administered in utero. Upon birth of the sheep, the human hematopoietic stemcells produce differentiated human blood cells in the lymphoid erythroid and myeloid lineages for at least two years. Thus, the sheep/human chimera is an… more
Abstract:Current assays from clinical quanititation of cytokines such as the interleukins, colony stimulating factors and erythropoietin (Epo) are based on monocional or polycional antibody recognition of the hormone on the form RIA's or ELISAs. This approach requires much time and effort to develop purified… more
Abstract:Due to both the rapid growth of genomic data and the inherent complexity and variability of its biological significance, automated pattern recognition is critical for efficiently identifying structural and functional relationships in the genomic databases that can be used to develop effective… more
Abstract:Management Communications and Control Incorporated (MCCI) proposes development of an innovative approach to acoustic signal full spectrum direction finding. The approach is based on describing full spectrum signal arrival structure as a distribution of energy about a single spatial frequency.… more
Abstract:MIKOS has developed proprietary techniques for identification of persons by means of facial thermography. A facial thermogram is a high-resolution temperature map of the face surface. It is obtained by use of a camera which is sensitive to infrared emissions rather than to visible light. The face… more
Abstract:THIS RESEARCH IS BASED ON THE THESIS THAT OXYGEN-FREE RADICALS CONTRIBUTE IN A SIGNIFICANT WAY TO THE DELETERIOUS ASPECT OF REPERFUSION AFTER A TISSUE OR ORGAN IS DEPRIVED OFOXYGEN AND FLOW IS RE-INITIATED. THE OBJECTIVE OF THIS RESEARCH IS TO DETERMINE THE POTENTIAL OF A NEW SERIES OF COMPOUNDS TO… more
Abstract:THE AVAILABILITY OF MASSIVE DATA STORAGE AND HIGH-SPEED INFORMATION GATHERING SYSTEMS AGGRAVATES THE EXISTING PROBLEM OF PROCESSING AND CORRELATING THE DATA. INDEED^ THE PROCESSING AND CORRELATION REQUIREMENTS EXCEED THE CAPABILITIES OF BOTH HUMAN LIBRARIANS AND "FIRST-GENERATION" SOFTWARE. THE… more
Abstract:REMOTE, RELIABLE ACCELEROMETERS SUITABLE FOR DEPLOYMENT ON THE OCEAN FLOOR ARE NEEDED FOR GEOPHYSICAL STUDIES. AN ALL-OPTICAL, REMOTE FIBER-OPTIC ACCELEROMETER SYSTEM THAT REQUIRES NO ELECTRICAL CONDUCTORS OR CONNECTIONS IN THE WATER IS BEING INVESTIGATED. THE ACCELEROMETER SYSTEM PROVIDES THE… more
Abstract:HYDRAULIC COMPONENTRY FOR AIRCRAFT BOMB RACK AND MISSILE LAUNCHER SYSTEMS REQUIRING VERY HIGH HYDRAULIC PRESSURES ARE BEING DEVELOPED, HOWEVER, TYPICALLY THE COMPONENT WEIGHT IS HIGH AND THERE IS A STRONG DESIRE TO INVESTIGATE METHODS TO REDUCE THE TOTAL WEIGHT. COMPONENTS MADE OF COMPOSITES AND… more
Abstract:This SBIR is directed to the application of image enhancement techniques to coherent two dimensional transformation of the acoustic time series to enhance low-level, stable signal components from diesel-electric submarines and suppress interference. The transformation are invertable and the final… more
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