Abstract:The objective of this Phase I STTR proposal is to demonstrate the effectiveness of a several highly porous silica-based solids in the presence of chemical challenges from chemical warfare agents (CWAs) and toxic industrial chemicals (TICs). In Phase II, the most effective solids will be combined… more
Abstract:The Department of EnergyÂ¿s (DOE) remediation efforts have relied on numerical models to integrate laboratory and field characterization data, predict the fate and transport behavior of contaminant plumes, design remediation protocols to mitigate contaminant migration, and analyze data from field… more
Abstract:DESCRIPTION (provided by applicant): Our research is focused on the potential of acid-prepared mesoporous silica (APMS) as a delivery agent for siRNA constructs to inhibit the ERK1/2 and ERK5 pathways in the treatment of human malignant mesothelioma (MM).
These pathways are critical to MM cell… more
Abstract:"Expanding demand for organic produce is driving a need for larger quantities of
commercially-available organic seed. Concomitantly, organic producers wish to have the
superior qualities realizable in first-generation (F1) hybrids for many crops. This SBIR
project seeks to develop a cost-effective,… more
Abstract:DESCRIPTION (provided by applicant): Abstract Cell culture bioassays are often laborious and imprecise even after substantial development efforts. These bioassays are used broadly in the biotechnology industry to measure protein or vaccine products in deve
lopment and for lot release. Imprecise… more
Abstract:DESCRIPTION (provided by applicant): Full participation in the human social milieu requires that one be able to understand that other people have their own goals, intentions, and beliefs (which may or may not be correct) - and that these epistemic states g
overn people's behavior. This form of… more
Abstract:DESCRIPTION (provided by applicant): Rigorous quantification methods of histological specimens have become a keystone in modern neuroscience such as investigations of neurogenesis, stem cell research, neurotransplantation, neurotoxicology, and the pathogen
esis of neurodegenerative and… more
Abstract:DESCRIPTION (provided by applicant): Supervised group exercise has been shown to be an effective component for improving balance and preventing falls among elders who have suffered falls or exhibit a fear of falling due to frailty. In a Phase I SBIR study,
we developed a model for conducting group… more
Abstract:Embedded wireless sensors for corrosion monitoring of critical aircraft components are needed for improved condition based maintenance and future structural health monitoring (SHM) systems. The objective of this Phase I SBIR proposal is to design, develop, and test a corrosion measurement and data… more
Abstract:In the proposed work, we will develop a highly efficient and miniaturized vibration energy harvesting device suitable for use on drive system components of helicopters. The goal is to provide power to run a wireless corrosion hub and sensors (to be developed simultaneously in a separate program). … more
Abstract:Omni Measurement Systems, Inc already has a proposed solution to the liquid waste portion. Omni developed an extended wear, semi-automatic bladder relief device for aircrew through Air Force/Small Business Innovative Research (SBIR) Phase I, Phase II, Phase II Enhancement and Phase III contracts. … more
Abstract:Standoff detectors are required to detect IEDs. These detectectors are needed to save the lives of American soldiers. QuantaSpec has developed patent pending methods for long-range, sensitive, and selective standoff detection of explosives. These methods have already demonstrated sensitive remote… more
Abstract:Hybrid Electric Vehicles (HEVs) and plug-in Hybrid Vehicles (PHEVs) require advanced technology capacitors, which must have low cost and the ability to operate at 150oC. However, current 150oC film capacitor solutions are expensive and have lower energy density compared to materials that operate at… more
Abstract:The objective of this proposal is to develop a reliable method to obtain reduced-order models for the simulation of large-scale seismic and acoustic signature propagation. These reduced-order models should be capable of reproducing results comparable to those obtained from a high-fidelity… more
Abstract:DESCRIPTION (provided by applicant): The long term goal of this project is to establish the usefulness of needle torque measurements for the diagnosis and monitoring of connective tissue pathology associated with chronic musculoskeletal conditions treated
by manual therapies. This project will… more
Abstract:This Small Business Innovation Research (SBIR) Phase I research project undertakes a major improvement in the cost-benefit equation of learning computer programming. The approach integrates a new programming paradigm particularly suited to real-time, high-interactivity applications, with advances in… more
Abstract:This Small Business Innovative Research Phase I research project aims to develop a visual interface that allows students to construct and investigate mathematical models. This research is undertaken with the goal of creating a general-purpose environment in which students, teachers, and materials… more
Abstract:This SBIR effort will show feasibility of very thin, lightweight, integrated FPAs on a novel, flexible substrate which can double as the IR transmissive window and be readily transferred onto curved or conformal surfaces, or structural elements of a Micro-Air Vehicle (MAV). Versatilis will build and… more
Abstract:Historically, remediation efforts at DOE contaminated sites have relied on numerical models to integrate laboratory and field characterization data, predict the fate and transport behavior of contaminant plumes, design remediation protocols to mitigate contaminant migration, and analyze data from… more
Abstract:DESCRIPTION (provided by applicant): The broad, long term objective of this application is to overcome optical design, ergonomic and cosmetic obstacles standing in the way of innovative ophthalmic lens designs for low vision enhancement, particularly field expansion for Homonymous Hemianopsia. Phase… more
Abstract:UHF radar is used for surveillance from unmanned aerial vehicles (UAVs). A typical transmitter must produce multi-kilowatt pulses, but the efficiency of existing transmitters is only 20 to 30 percent. Low efficiency results in transmitters that are unnecessarily large and heavy. It also taxes the… more
Abstract:DESCRIPTION (provided by applicant): The goal of this application is to develop a comprehensive system for the acquisition and quantitative analysis of focusable (3D) virtual slides. A 3D virtual slide is a complete digital representation of a tissue specimen imaged through a microscope,… more
Abstract:The goal of this Phase II SBIR proposal is to design, build, test, and demonstrate next generation energy harvesting wireless sensors for real time load measurement and structural damage tracking on helicopters. Energy harvesting allows the realization of wireless monitoring systems that do not… more
Abstract:DESCRIPTION (provided by applicant): The focus of this Phase II proposal is a computer-based method called the Dynamic Assessment of Hearing Aids (DAHA). The method uses an intuitive graphical interface to record visual analogue ratings of a patient's satisfaction with various facets of his/her… more
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