Abstract:IMMUNE COMPLEXES (IC) PLAY AN IMPORTANT ROLE IN THE PATHOGENESIS OF CERTAIN HUMAN DISEASES, SUCH AS SERUM SICKNESS, GLOMERULONEPHITIDES, AND LUPUS ERYTHEMATOSUS, AND ARE ALSO ASSOCIATED WITH RHEUMATOID ARTHRITIS AND A VARIETY OF VASCULITIDES. PRESENT TESTS FOR THE DETECTION OF IC RELYON… more
Abstract:THIS PROPOSAL IS FOR EXTENDING STUDIES RELATED TO THE EVALUATION OF POLYCATION HEXADIMETHRINE (HDM) AND ITS COMPONENTS AS ANTICANCER AGENTS. THESE INVESTIGATORS HAVE DEMONSTRATED A DIFFERENTIAL EFFECT OF HDM ON MIXED LYMPHOCYTE CELL CULTURE (MLC) AND ON L1210 CELLS. AT THE DOSES WHICH INHIBIT… more
Abstract:THE OBJECTIVE OF THE PROPOSED RESEARCH IS TO DEVELOP AN IMMUNOLOGICALLY SPECIFIC ADSORBENT FOR USE IN EXTRACORPOREALSYSTEMS TO REMOVE IMMUNOREACTIVE IGM FROM THE SERUM OF PATIENTS FOR PRIMARY BILIARY CIRRHOSIS (PBC). BY STANDARD IMMUNOLOGIC TECHNIQUES, ANTIBODIES TO HUMAN IGM WILL BE ISOLATED. THESE… more
Abstract:THIS PROPOSAL PRESENTS A PROGRAM TO RESEARCH THE TECHNICAL FEASIBILITY OF AN OCEANOGRAPHIC INSTRUMENT CAPABLE OF DRILLING AND RETRIEVING 40 METER CORE SAMPLES FROM SELECTED BARE ROCK SITES ON THE DEEP OCEAN SEAFLOOR. TO MEET THE NEEDS OF THE SCIENTIFIC COMMUNITY THIS DEVICE SHOULD BE PORTABLE AND… more
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