Abstract:DESCRIPTION (provided by applicant): Tramadol is a widely prescribed analgesic, with over 25 million prescriptions and 565 million in retail sales in 2009, making it among the best selling generic drugs. One of the advantages of tramadol over traditionalopioids is its lower risk of opioid… more
Abstract:Systima is developing a high performance 25 lbf DACS thruster that operates with a novel non-toxic monopropellant. The monopropellant has a 30% higher density-specific impulse compared to hydrazine and is commercially available off-the-shelf. In Phase I Systima will focus on development of the… more
Abstract:Systima is developing an IM compliant High Performance Green Propellant (HPGP) DACS thruster that operates with a novel non-toxic monopropellant. The monopropellant has a 30% higher density-specific impulse compared to hydrazine, insensitive/ not a detonation hazard, and is commercially available… more
Abstract:Systima Technologies, Inc. (Systima) is proposing to develop an end-to-end integrated All-Up-Round (AUR) canister solution to provide a multiple missile launcher (MML) for Extended Area Protection & Survivability (EAPS) missiles. By allowing a single MML-AUR to provide multiple EAPS missiles the… more
Abstract:DESCRIPTION (provided by applicant): Primary Care Providers (PCPs) have the opportunity to identify and intervene with alcohol abusers and risky users at an early stage, preventing many negative health and societal consequences. Screening and brief intervention (SBI) for substance use problems is an… more
Abstract:DESCRIPTION (provided by applicant): Approximately one-third of those who turned 65 in 2010 will enter a nursing home for short or long-term stay in their lifetime. Although the older adult population is growing more diverse, the current population of nursing home residents is 86% White and 62%… more
Abstract:DESCRIPTION (provided by applicant): Modifiable behavioral risk factors for diabetes and cardiovascular disease, two of the most costly diseases in both human and monetary terms, include obesity, lack of physical activity, smoking tobacco and excess alcohol consumption. Despite a longstanding… more
Abstract:A majority of rainbow trout produced in the US are derived from all-female stocks due to improved harvest traits and efficiency over mixed sex stocks. The development of all-female stocks currently relies on the use of the testosterone derivative 17 & #945; & #8722;methyltestosterone,… more
Abstract:This proposal addresses the problem of long term mapping and monitoring of subsurface geochemical and microbial activity associated with the transport and remediation of subsurface contaminants, including radionuclides and metals. The ability to map and monitor bioremediation processes in the near… more
Abstract:Vista Clara proposes to design, develop and demonstrate non-invasive NMR sensor capable of profiling moisture content in the top 2m of the subsurface. As a Phase 1 option, Vista Clara proposes to design, assemble and demonstrate a minimally-invasive NMR sensor for profiling moisture content in the… more
Abstract:DESCRIPTION (provided by applicant): Gene-expression reporter assays bridge bioinformatics data with gene-specific bioassays to monitor effects of ligands, compounds, antibodies, siRNAs, miRNAs, and peptides on gene expression. In cell culture, they provide for bench top or high throughput screening… more
Abstract:DESCRIPTION (provided by applicant): Project Summary/Abstract Current radioembolic Y-90 microspheres have been generally recognized as the state-of-the-art for treating primary and metastatic liver tumors. However, the clinical results vary vastly dueto the lack of accurate diagnostic imaging… more
Abstract:ABSTRACT: State of the art Orbital Transfer Vehicle systems require the demanding combined requirements of both high Thrust-to-Power (greater than 120 mN/kW) and high specific impulse (greater than 3000 s), all at constant power. The 25 kW PROTEAN system is a two-stage plasmoid thruster which adds… more
Abstract:ABSTRACT: MSNW"s Electrodeless Lorentz Force (ELF) thruster will address the demanding combined requirements of light weight, high efficiency, and high thrust-to-power electric propulsion in a single device. As spacecraft power systems get lighter, traditional electric propulsion thruster, PPU… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will result in a commercially viable network of low cost wireless sensors that predict electric motor failure before failure occurs. American industries and manufacturers rely heavily on electric motors to power their equipment and… more
Abstract:DESCRIPTION (provided by applicant): At the frontier of biological electron microscopy, there is a strong emphasis on imaging the 3-D structure of cells, organelles, and macromolecules in their native state. This is facilitated by the use of frozen-hydrated specimens which have not been… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project addresses a fundamental problem with Magnetic Particle Imaging, a promising, yet new imaging modality. MPI uses magnetic nanoparticles (tracers) to generate a signal that can be used for fast, safe, non-invasive 3D imaging in living… more
Abstract:CustomArray produces a field-deployable electrochemical microarray platform ideally suited for the multiplexed detection of pathogenic organisms. In this Phase II proposal, we will continue our Phase I effort to build an automated arthropod-borne virus detection system. The Phase I assay work-flow… more
Abstract:Under this Small Business Innovative Research (SBIR) Phase II project, the Contractor shall create software that enables substance abuse researchers and other psychologists to administer neuropsychological tests over the web with the same timing precisionas traditional computer-administered measures… more
Abstract:The emerging field of visual analytics, which integrates analytical reasoning with interactive visualization, appears to be a promising technique for improving the business practices in todays electric power industry. The conducted investigation has revealed that the existing commercial power grid… more
Abstract:ABSTRACT: We have designed a system we call the Human Terminal System - a wrist-or-chest wearable system to provide organic battlespace visualization capability to pilots and other warfighters. The system is a powerful, miniaturized, man-wearable, multi-processor PC running Windows and Android in… more
Abstract:ABSTRACT: In this project, Soluxra, LLC will team up with Prof. Alex Jen at the University of Washington to streamline the scale-up synthesis for highly efficient organic electro-optic (EO) material systems, and optimize their processing conditions to ensure device end-users will get high EO… more
Abstract:Infinia Technology Corporation's (ITC) proposed Modular Stirling Power System (MSPS) is a free-piston Stirling system that addresses NASA needs in 12-kW increments. The MSPS utilizes a support structure that couples 1 heater head with 4 power modules and provides a high efficiency of 25%… more
Abstract:For DoD tactical operations, reducing fuel usage and maintenance associated with electric power generation is a key need. Concentrated solar thermal (CST) systems are an attractive renewable energy solution due to their high net average efficiencies of solar-to-electric conversion, and they have the… more
Abstract:DESCRIPTION (provided by applicant): HIV/AIDS is a global epidemic afflicting more than 33 million people worldwide. HIV can often be suppressed for many years with anti-retroviral medications, and over 15 billion dollars were spent on these medications in2010. Biologics such as HIV-1 neutralizing… more
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