Abstract:This Small Business Technology Transfer (STTR) Phase I project will develop a facultative anaerobic bacterium that ferments sugars obtained from cellulosic sources into isoprene, a valuable feedstock used in the production of latex rubber, plastics, and pharmaceuticals. Isoprene also is used for the… more
Abstract:Vacuum glazing has been on the market for over a decade, but its performance is poor, and its cost too high for wide adoption. Both issues stem from the use of a hard glass edge seal, which requires a high temperature manufacturing process, and which does not flex to accommodate outer pane… more
Abstract:Obesity is a growing epidemic that threatens the health of both adults and children. The problem is exacerbated by challenging economic times and increasing food costs that put pressure on consumers to purchase lower priced meals, which may be of inferior nutritional value and/or contain excessive… more
Abstract:FOREST-TO-FACTORY: ROUND TIMBER SUPPLY CHAIN TOOLS AND TECHNIQUES USDA secretary, Tom Vilsack has urged the Forest Service to "develop new markets" for forest by-products, which encourage healthy timber management. WholeTrees® Architecture & Structures (WT) is commercializing a line of round… more
Abstract:The desire and benefit to improve the environment through the use of advanced electric drive vehicles is hampered by the high cost and associated manufacturing hazards associated with the manufacture of lithium ion batteries. The use of solvents in the lithium ion battery manufacturing process… more
Abstract:We propose to design and implement a query-based approach to interoperable modeling and simulation of composite material structures, that usually contain the manufacturing recipe within their design. In Phase I, we established the feasibility of the approach using a demonstration scenario of CAD/CAE… more
Abstract:Johne & #39;s disease (JD) or paratuberculosis in animals (infection with M. avium ss. paratuberculosis, M. ap) is a contagious, chronic, and potentially fatal disease affecting the small intestine of ruminants. All ruminants are susceptible, but the largest economic impact is felt in dairy… more
Abstract:DESCRIPTION (provided by applicant): Evaluation of dental tobacco cessation tool in practice-based research network This Phase II project will finish development and evaluate QuitAdvisorDDS as a tool for dental providers to advise patients on tobacco cessation. The University of Kentucky will… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will develop robust manufacturing methods to commercialize novel biobased plastics made from scrap PLA resins, resulting in a new method to effectively address end-of-life management of bioplastics, specifically polylactic acid (PLA).… more
Abstract:This Small Business Innovation Phase I project proposes to develop technology and products that will eliminate the use of polyvinylchloride (PVC) in one of its largest volume uses, flooring materials. Interfacial Solutions has recently demonstrated that a high volume low cost plastic waste stream… more
Abstract:DESCRIPTION (provided by applicant): Implementation of evidence-based prescriptive exercise practices in rehabilitation therapy demands an objective muscular strength assessment method that is fast, reliable, portable, cost effective, and kinetic (i.e., able to test the full rnge of motion). It… more
Abstract:Flexible electronic and optical devices, including sensors/detectors, waveguides, and photonic crystal structures, have significant promise for improving communication and information processing capabilities in a number of military and commercial applications. However, the development of such… more
Abstract:This Small Business Technical Transfer (STTR) Phase I project will demonstrate the potential for developing a novel affinity binding reagent screening technology. Synthetic affinity binding reagents can improve on immunoglobulin-based antibodies. For example, synthetic affinity binding reagents are… more
Abstract:The unique built-in design features of the proposed mini pulse tube cryocooler avoid all thermal expansion issues enabling it to operate within a cold, 150 K environment. As such, the cooler addresses the need to prevent boiloff of cryogenic propellants on long duration remote missions.Due to its… more
Abstract:PROJECT SUMMARY/ABSTRACT My Coverage Plan Inc. (MCP) proposes to use our newly patented technology to create a commercially viable and nationally replicable suite of software and services for health care providers and other social service agencies that reduces avoidable health disparities and… more
Abstract:This Small Business Innovation Research (SBIR) Phase 1 project will develop an ultra-low power reconfigurable hardware watchdog preprocessor for identifying and acting upon spatial and temporal trigger signatures (events of interests) in continuous sensory data streams. The proposed approach… more
Abstract:Blood-based assays require upstream mechanisms to acquire sample from a patient, extract the analyte of interest, and preserve the analyte until it can be quantified. Current point-of-care assays overwhelmingly rely on lancet puncture, which is inconvenient because of the presence of blood that is… more
Abstract:DESCRIPTION (provided by applicant): Economic, logistical, and physical barriers limit HIV viral load quantification, the gold standard for HIV diagnostics. The cost of the test is high (approximately 100 per test) and the intricate equipment required limits testing to laboratories staffed by… more
Abstract:The project team is developing a prototype of an application (app) for a tablet computer called Access: Language Arts. The app will support middle school students with significant learning disabilities in meeting Common Core State Standards in English Language Arts. The intervention will be designed… more
Abstract:Significance: Accurate targeting, guidance and monitoring of interventional therapy in the brain are critical for maximizing the effectiveness and safety during and following neurosurgical procedures. Magnetic resonance imaging (MRI) is a critical tool forplanning and guiding neurosurgical… more
Abstract:DESCRIPTION (provided by applicant): Healing of Diabetic Ulcers with Gaseous Nitric Oxide Generated from Room Air Diabetic foot ulcers (DFUs) are a frequent and debilitating complication of diabetes, and affect 1-2.5 million patients in the US. Many DFUs remain unhealed, leading to extensive… more
Abstract:DESCRIPTION (provided by applicant): The objective of this Phase I SBIR project is to design, develop and evaluate a wearable Muscle Fiber Excitation System (MFES) for preventing blood clot in immobilized patients during convalescence following lower limborthopedic surgery. The MFES device will be… more
Abstract:Facing strict effluent limits, municipal wastewater treatment facilities are dealing with increasing costs of treating phosphorus in their waste. Current technologies are capable of sequestering the phosphorus in an unusable form or capturing only a fraction of it. Nutrient Recovery and Upcycling,… more
Abstract:The technical objectives of this proposal are: 1) the design of 3.0-3.5 micron-emitting quantum cascade laser (QCL) structures grown on metamorphic-buffer-layer (MBL) substrates; 2) the realization of electroluminescent QCL structures on MBLs with emission in the 3.0-3.5-micron wavelength range.… more
Abstract:The technical objectives of this proposal are: 1) Implement the design developed in Phase I for the realization of 8 micron-emitting active-photonic-crystal (APC) quantum-cascade (QC) lasers of 3 W average, diffraction-limited power and 15 % wallplug efficiency in quasi-CW operation; 2) Design and… more
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