Abstract:ORBITEC proposes to continue the development of the SYREN Igniter to meet the performance goals of the next generation of liquid hydrocarbon boost and upper stage rocket engines. This effort will advance the technical readiness level of an innovative family of igniters for rocket combustion devices… more
Abstract:Plant-eating insect pests cause significant economic loss in commercial greenhouse growing operations, sometimes amounting to tens of thousands of dollars per hectare. Insects as a vector of plant pathogens also rank very high on the problem list for greenhouse/hothouse growers. Integrated Pest… more
Abstract:The Center for Disease Control (CDC) estimates that foodborne diseases cause 76 million illnesses and 5,000 deaths in the United States each year. Among outbreaks for which the cause was determined, bacterial pathogens caused the largest percentage of outbreaks (55%) and the largest percentage of… more
Abstract:This project addresses the potential to move power requirements for ornamental crop lighting systems off the grid and to alternative energy sources such as solar photovoltaic. Photoperiod lighting is currently used in an estimated 25% of greenhouse ornamental production operations and floriculture… more
Abstract:DESCRIPTION (provided by applicant): The successful treatment of human cancer depends on the ability to find treatments that kill tumor cells without impacting normal tissue significantly. An alternative approach is to selectively protect normal tissue fro
m the toxic effects of chemotherapy while… more
Abstract:DESCRIPTION (provided by applicant): The number of patients in the United States afflicted with learning and memory disorders is rapidly increasing. This necessitates the development of new, better acting and safer medications for enhancing cognition. In
this SBIR Phase I project, PhysioGenix will… more
Abstract:DESCRIPTION (provided by applicant): The long term goal of this project is to develop a 384-well plate-based cell migration assay suitable for high throughput screening (HTS) of chemical libraries. The principal barrier to performing HTS to discover cancer
drugs affecting cell migration is the lack… more
Abstract:DESCRIPTION (provided by applicant): A primary goal in neuroscience is to understand at a mechanistic level the functioning of neuronal networks with specific behaviors. This involves in general, the anatomical connectivity among the various types of neurons within the local network, the… more
Abstract:DESCRIPTION (provided by applicant): Primorigen Biosciences will use Phase II SBIR funds to accelerate and expand the development of new regenerative medicine cell therapies by developing a novel high throughput, low cost protein quantification system for
characterizing pancreatic 2 cell and islet… more
Abstract:DESCRIPTION (provided by applicant): Primorigen Biosciences will use Phase II SBIR funds to accelerate and expand the development of new regenerative medicine cell therapies by developing a novel high throughput, low cost protein quantification system for characterizing pluripotent cell lines and… more
Abstract:DESCRIPTION (provided by applicant): Myelopathy secondary to cervical spondylosis is a common cause of disability, and the most common primary diagnosis for patients over 64 years who undergo cervical spine surgery. Some studies suggest that surgical inter
vention after neurological decline is… more
Abstract:The objective of this proposal is to develop advanced radiation transport modeling techniques that accurately and efficiently treat transport in media having widely varying optical properties; in particular, hot gases and plasmas with optical depths ranging from the optically thin to the optically… more
Abstract:Rxoa Biosciences (Rxoa) proposes to develop a fast, reliable, cost-effective assay for Potato Virus Y (PVY). The $3 billion per year US potato industry requires a reliable and healthy seed potato supply. PVY is one of the top disease management issues for the over 2 billion pounds of seed potatoes… more
Abstract:DESCRIPTION (provided by applicant): We have recognized an urgent need for a commercially applicable high throughput way to isolate pure DNA with long and uniform fragment length for nextgen genomic sequencing from precious samples. The advent of nextgen s
equencing has driven the cost of DNA… more
Abstract:DESCRIPTION (provided by applicant): Complications arising from pathogen infection incur a tremendous societal cost both in morbidity and mortality (as high as 50-60%), as well as in care and treatment estimated in billions of dollars. In susceptible patie
nts, infection induces mis-regulation of… more
Abstract:DESCRIPTION (provided by applicant): Over 1.1 million conceptuses and fetuses die spontaneously each year, nearly 28,000 after 20 weeks' gestation. 12.5% of all infants are delivered prematurely, and the cost of care for the prematurely born is nearly 27 b
illion dollars annually. Prenatal… more
Abstract:Silatronix has developed novel organosilicon compounds that can be used as drop-in replacements for conventional carbonate electrolytes in lithium-ion cells. These organosilicon electrolytes have very high flash points and have demonstrated superior stability and safety characteristics. In the… more
Abstract:Millimeter-wave tubes that operate in the 80 to 300 GHz range are important sources of microwave power for future communication, remote sensing, and electronic warfare applications. Effective computer design and optimization capabilities are required to develop these tubes due to their small size,… more
Abstract:DESCRIPTION (provided by applicant): The National Cancer Institute projects that more than 1,000,000 cases of skin cancer will be diagnosed in the United States in 2008, including more than 62,000 new cases of melanoma. Although surgical excision of the pr
imary tumor is curative for the majority of… more
Abstract:Complex craniofacial tissue loss is a major medical problem affecting deployed military personnel. During the ongoing conflicts in Iraq and Afghanistan, approximately 88% of injured troops sustain severe blast-related injuries to their head and neck from improvised explosive devices. These severe… more
Abstract:DESCRIPTION (provided by applicant): Burns and trauma to the skin affect an estimated 1.25 million Americans each year. Extensive damage to the skin has serious repercussions, leading to dehydration, increased metabolic load, entry of toxic substances, immunosuppression, and wound infection.… more
Abstract:DESCRIPTION (provided by applicant): Chronic and infected wounds significantly affect the quality of life for millions of US citizens and are associated with increased risk of complications including the devastating consequence of amputation. As of 2006, i
nfections of diabetic foot ulcers resulted… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project proposes to develop a full-thickness in vitro human skin model in a format enabling increased-throughput screening of compounds. The project will 1) develop culture conditions for production of fibroblast-derived dermal equivalents, 2)… more
Abstract:DESCRIPTION (provided by applicant): The goal of this STTR project is to develop innovative human tumor microenvironment (TM) assays for use as screening tools in the identification of new anti-tumor therapeutics. Novel assay technologies are needed for the discovery of new drugs, and combinations… more
Abstract:Summerdale, Inc. and Forest Products Laboratory (FPL) will focus on above-ground applications of waterborne preservatives for indoor and outdoor residential lumber. Specifically, fatty acid-based formulations +/- adjuvants will be targeted for use on a) indoor lumber and wood composites and b)… more
There are several categories such as “By Agency”, “By Year”, “By State” etc.
Select a checkbox within a category to refine your search results.
Each of your selections is listed in the “Narrow Search Filters” bar. You can uncheck these selections to remove them.
Search for Either Criteria
When you select multiple values within a category, the results will include values that match either of the selections.
For example, selecting “2005” and “2007” in the “By Year” category will display results that include either 2005 OR 2007 in the results.
Narrowing the Search Results
You can refine your search results across categories. To narrow down your results, select multiple values across different categories. The results will only include values that match the selections across the categories.
For example, selecting “2005” in the “By Year” category and “NASA” in the “By Agency” category will only display the results that contain both “2005” AND “NASA” in the results.