USA flag logo/image

An Official Website of the United States Government

Search

Note: The awards database is continually being updated to reflect accurate data as agencies upload their award information

Narrow Search Filters:
State:CaliforniaColoradoTexasOregonUtahNew MexicoArizona
Download to spreadsheetPrint
Displaying 76 – 100 of 124 Awards
Company: Alexza Molecular Delivery Corporation Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: … quickly into the blood stream via injection. The utility of this form of treatment is, however, limited due to its invasiveness and the inability of many late-stage Parkinson's disease patients to self-administer injections. The aim of this project is to develop an … more
Company: Alexza Molecular Delivery Corporation Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: … is to develop and commercialize a nicotine replacement product that more effectively relieves cigarette craving by delivering nicotine with similar pharmacokinetics to those produced by cigarette smoking. Such rapid, pulsatile nicotine delivery would be achieved via inhalation… more
Company: Alexza Molecular Delivery Corporation Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: … (IV) delivery of loop diuretics provides more rapid and complete relief, with many hospital visits primarily to obtain this benefit. The goal of this proposal is to develop a device that rapidly delivers loop diuretics into systemic circulation via deep lung inhalation,… more
Company: Alexza Molecular Delivery Corporation Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: … techniques is relatively slow onset of drug action. There is thus a clear medical need for rapid, non-invasive techniques to treat acute agitation. The goal of this proposal is to develop a device that rapidly delivers agitation treatment via deep-lung inhalation. Our… more
Company: Alexza Molecular Delivery Corporation Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: … successful by marginally accelerating the onset of breakthrough pain treatment relative to oral opioids. However, there remains a substantial unmet need for a faster onset treatment with minimal side effects. The goal of this proposal is to develop an inhalation device… more
Company: Alexza Molecular Delivery Corporation Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: … attacks characterized by wheezing and shortness of breath. Around 5% of the population in the United States suffers from asthma, with the prevalence of this disease continuing to rise. The most common method to deliver asthma medications to patients is metered dose inhalers… more
Company: BIOTECHPLEX CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): Of the 30 million US patients who suffer from respiratory disorders, over 4 million require frequent inhaled medication. Therapy sessions can last from several minutes to 3 hours. In addition, inhaled drugs are increasingly used to deliver… more
Company: ICHOR MEDICAL SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): Anthrax, an infectious disease caused by Bacillus anthracis, became a pressing concern because of its potential biowarfare use, most likely via aerosolized anthrax spore dissemination, resulting in deadly inhalation anthrax. The current… more
Company: LIFETECHNIQUES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: … will develop and fabricate a prototype that is a highly advanced, non-invasive, child-friendly system that is especially functional for critically or chronically ill children. Its soft pouch container will accommodate a variety of medicine forms, including pills, inhalants,… more
Company: OPERATIONAL TECHNOLOGIES CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by investigator): The anti-phagocytic poly-D-glutamic acid (PDGA) capsule of Bacillus anthracis is a major virulence factor of inhalation anthrax. Although generation of antibodies to PDGA might be of value in opsonizing vegetative anthrax, such antibodies… more
Company: Alexza Molecular Delivery Corporation Agency/Program/Year/Phase: HHS / SBIR / 2003 / 2
Abstract: … extensive first pass metabolism and resulting inconsistent oral bioavailability. In Phase I of this grant application, we have demonstrated the ability to form high purity, small particle size aerosols of dronabinol for reliable systemic delivery through inhalation. These… more
Company: Alexza Molecular Delivery Corporation Agency/Program/Year/Phase: HHS / SBIR / 2003 / 2
Abstract: …tion affecting millions of Americans. Patients with migraine strongly desire more rapid headache relief than current medications provide. A promising approach to expediting pain relief is delivery of existing drugs to the systemic circulation more rapidly via aerosol inhalation.… more
Company: Alexza Molecular Delivery Corporation Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: … for "off' periods are dopamine agonists, with the dopamine agonist apomorphine especially effective. Apomorphine, however, suffers from low oral bioavailability and a low therapeutic index, which limit its clinical use. The aim of this proposal is to develop inhalation… more
Company: ARADIGM CORPORATION Agency/Program/Year/Phase: DOD / SBIR / 2003 / 1
Abstract: … BChE formulation that will deliver the target systemic dose via the lungs; 2) to ensure that the integrity of the BChE protein is unaffected by the aerosolization process; and 3) to measure the efficiency ofdelivering BChE to the systemic circulation via inhalation using the… more
Company: ICHOR MEDICAL SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): Anthrax suddenly became a pressing public health issue due to the present terrorist crisis. Its use as biological weapon causes death by inhalational anthrax, due to exotoxins produced by anthrax bacteria. The current vaccine has significant… more
Company: ICHOR MEDICAL SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): Anthrax, an infectious disease caused by Bacillus anthracis, became a pressing concern because of its potential biowarfare use, most likely via aerosolized anthrax spore dissemination, resulting in deadly inhalation anthrax. The current… more
Company: Lynntech, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): The technology proposed herein describes an analytical tool for the rapid detection of inhalation anthrax prior to the onset of clinical symptoms. This potentially lethal disease can be fully suppressed in those who are administered… more
Company: Nexbio, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: … will also overcome the side effects and the risk of generating drug-resistant viruses associated with the current antiviral compounds. Finally, the new class of therapeutics/prophylactics will be delivered locally and topically as a nasal spray/inhalant… more
Company: PLANET BIOTECHNOLOGY, INC. Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): Our overall goal in this project is to make available in large quantity an inexpensive recombinant protein that protects against the cellular toxicity associated with inhalational (pulmonary) anthrax. We will combine our experience in… more
Company: VOC Technologies Agency/Program/Year/Phase: HHS / SBIR / 2003 / 2
Abstract: …, ethanol, acetone, methyl acetate, and isoprene. Their concentrations range from 80 nmol/L for methane to 400 pmol/L or less for methyl acetate. More than 1000 additional compounds have been reported present in human breath, many originating in the inhaled air. Exposure… more
Company: MYCOLOGICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: …, southern New Mexico and west Texas. The migration of not only permanent residents, but also agricultural workers to these areas increases exposure to C. immitis spores that lie dormant in the soil, and as the soil is turned, the spores become airborne and are inhaled. … more
Company: OMNISITE BIODIAGNOSTICS, INC. Agency/Program/Year/Phase: DOD / SBIR / 2003 / 1
Abstract: OmniSite BioDiagnostics Inc. proposes to determine the feasibility of using DNA Aptamers to bind key germinant receptors on nonpathogenic Sterne strain anthrax spores to induce synchronous germination, hence leading to more effective antibiotic treatmentof inhalation anthrax. … more
Company: ADVANCED MRI TECHNOLOGY, LLC Agency/Program/Year/Phase: HHS / SBIR / 2002 / 1
Abstract: We are proposing the development of an MRI pulse sequence package based on the recently invented Xenon Polarization transfer Contrast (XTC) MRI. Upon inhalation of a batch of hyperpolarized 129Xe, the lipophilic xenon dissolves almost instantaneously in the lung tissue and the… more
Company: Aerophase, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2002 / 1
Abstract: DESCRIPTION (Applicant's abstract): Asthma is one of the most common and costly illnesses in the United States, and drug formulation delivered via metered inhalers (MDIs) represent the primary treatment method for asthma sufferers. A key current issue in this arena is that the… more
Company: Aerophase, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2002 / 1
Abstract: DESCRIPTION (provided by applicant): Delivery of anticancer drugs as inhaled aerosols is an attractive possibility for the treatment of lung cancer. Many of the agents that exhibit inhibitory activity towards cancer cell growth are lipophilic, including topotecan, taxol,… more
Displaying 76 – 100 of 124 Awards
Narrow Your Search
By Agency
By Year
By Phase
By Program
By State
By Company Ownership
By Company
HELP FOR NARROW YOUR SEARCH

Search Options

There are several categories such as “By Agency”, “By Year”, “By State” etc. Select a checkbox within a category to refine your search results.

Each of your selections is listed in the “Narrow Search Filters” bar. You can uncheck these selections to remove them.


Search for Either Criteria

When you select multiple values within a category, the results will include values that match either of the selections. For example, selecting “2005” and “2007” in the “By Year” category will display results that include either 2005 OR 2007 in the results.


Narrowing the Search Results

You can refine your search results across categories. To narrow down your results, select multiple values across different categories. The results will only include values that match the selections across the categories. For example, selecting “2005” in the “By Year” category and “NASA” in the “By Agency” category will only display the results that contain both “2005” AND “NASA” in the results.