USA flag logo/image

An Official Website of the United States Government

Search

Note: The Award Database is continually updated throughout the year. As a result, data for a given year is generally not complete until April of the following year.

Narrow Search Filters:
State:CaliforniaColoradoTexasOregonUtahNew MexicoArizona
Download to spreadsheetPrint
Displaying 101 – 125 of 129 Awards
Company: OMNISITE BIODIAGNOSTICS, INC. Agency/Program/Year/Phase: DOD / SBIR / 2003 / 1
Abstract: OmniSite BioDiagnostics Inc. proposes to determine the feasibility of using DNA Aptamers to bind key germinant receptors on nonpathogenic Sterne strain anthrax spores to induce synchronous germination, hence leading to more effective antibiotic treatmentof inhalation anthrax. … more
Company: Lynntech, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): The technology proposed herein describes an analytical tool for the rapid detection of inhalation anthrax prior to the onset of clinical symptoms. This potentially lethal disease can be fully suppressed in those who are administered… more
Company: ADVANCED MRI TECHNOLOGY, LLC Agency/Program/Year/Phase: HHS / SBIR / 2002 / 1
Abstract: We are proposing the development of an MRI pulse sequence package based on the recently invented Xenon Polarization transfer Contrast (XTC) MRI. Upon inhalation of a batch of hyperpolarized 129Xe, the lipophilic xenon dissolves almost instantaneously in the lung tissue and the… more
Company: Aerophase, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2002 / 1
Abstract: DESCRIPTION (Applicant's abstract): Asthma is one of the most common and costly illnesses in the United States, and drug formulation delivered via metered inhalers (MDIs) represent the primary treatment method for asthma sufferers. A key current issue in this arena is that the… more
Company: Aerophase, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2002 / 1
Abstract: DESCRIPTION (provided by applicant): Delivery of anticancer drugs as inhaled aerosols is an attractive possibility for the treatment of lung cancer. Many of the agents that exhibit inhibitory activity towards cancer cell growth are lipophilic, including topotecan, taxol,… more
Company: Alexza Molecular Delivery Corporation Agency/Program/Year/Phase: HHS / SBIR / 2002 / 1
Abstract: …, variable absorption, poor bioavailability, slow onset of action, and toxic components and legal issues if smoked. Medical experts agree that a rapid-onset, reliable and safe delivery system for THC represents an unmet patient need. MDC proposes its hand-held inhaler to… more
Company: Alexza Molecular Delivery Corporation Agency/Program/Year/Phase: HHS / SBIR / 2002 / 1
Abstract: …tion affecting millions of Americans. Patients with migraine strongly desire more rapid headache relief than current medications provide. A promising approach to expediting pain relief is delivery of existing drugs to the systemic circulation more rapidly via aerosol inhalation.… more
Company: MesoSystems Technology, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2002 / 1
Abstract: … body due to respiration. The mesochannel adsorption water-recovery device will utilize a state-of-the-art, high-capacity adsorbent to separate water vapor from the soldier'sexhaled air. The water vapor will then be desorbed into the airflow as the soldier inhales. … more
Company: RxKinetix, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2002 / 1
Abstract: …I study demonstrates production of toxin neutralizing antibodies and lack of adverse reactions in animals, these data will be used to develop a Phase II study in which these formulations will be evaluated for their ability to elicit protection in rabbits following inhalation… more
Company: VICAL, INC. Agency/Program/Year/Phase: HHS / STTR / 2002 / 1
Abstract: … factor (LF) protects mice from an intravenous challenge using 5X the lethal dose of toxic protein. Based on this work and subsequent work (presented here) showing that a similar DNA vaccination protocol can protect rabbits from a more rigorous spore inhalation challenge,… more
Company: VOC Technologies Agency/Program/Year/Phase: HHS / SBIR / 2002 / 1
Abstract: …, ethanol, acetone, methyl acetate, and isoprene. Their concentrations range from 80 nmol/L for methane to 400 pmol/L or less for methyl acetate. More than 1000 additional compounds have been reported present in human breath, many originating in the inhaled air. Exposure… more
Company: Lynntech, Inc. Agency/Program/Year/Phase: NSF / SBIR / 2002 / 1
Abstract: …l biofilm from the surfaces of tubing within dental-unit water systems. Persons who are immunocompromised may be at risk due to some opportunistic microorganisms present in most biofilm. Contaminated water may be ingested by the patient or be aerosolized and inhaled by the… more
Company: Aerophase, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: DESCRIPTION (Adapted from the Investigator's Abstract): The chlorofluorocarbon (CFC) propellants currently being used in metered dose inhalers for pulmonary drug delivery are being phased out due to their high ozone depletion potential. An international… more
Company: CYTOKINETICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: … rise as reflected by increasing mortality rates. The treatment of COPD and asthma relies on long-term reduction of the chronic inflammatory response and acute symptomatic control by the use of bronchodilators. In the latter class, inhaled Beta… more
Company: Seashell Technology Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: … when properly surface coated, can efficiently penetrate into cells, and thereby be used as therapeutic gene delivery vectors. The verification of the use of Plasmon Resonant particles for persistent labeling of impaction sites of inhaled… more
Company: INDIGO SYSTEMS CORP. Agency/Program/Year/Phase: DOD / SBIR / 1999 / 1
Abstract: … recommendations for costly procedure or hardware changes. Finally, completion of such a tool will allow, with little additional effort, a general-purpose code for the analysis of fire challenges and subsequent behavior (e.g., transport, decomposition, inhalation, and… more
Company: ARADIGM CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1998 / 2
Abstract: DESCRIPTION: (Adapted from the Applicant's Abstract). Inhaled gene products are desirable for chronic respiratory diseases with high morbidity and mortality, e.g. cystic fibrosis, emphysema, asthma, lung cancer, and tuberculosis. Aerosolization of DNA (plasmids) using… more
Company: SYNVAX Agency/Program/Year/Phase: HHS / SBIR / 1998 / 2
Abstract: … II studies will involve the synthesis of a metabocandidate peptide will be tested against different strains of type A and type B influenza viruses. Ttest the effect of the peptide on normal cellular functions. Pharmacokinetics, cell penetration, andbe conducted. An inhalation… more
Company: ARADIGM CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1997 / 1
Abstract: DESCRIPTION: (Adapted from the Applicant's Abstract). Inhaled gene products are desirable for chronic respiratory diseases with high morbidity and mortality, e.g. cystic fibrosis, emphysema, asthma, lung cancer, and tuberculosis. Aerosolization of DNA (plasmids) using… more
Company: ETALON, INC. Agency/Program/Year/Phase: HHS / SBIR / 1997 / 1
Abstract: … indeed possess dual antibronchoconstrictor/antiinflammatory activity, it could be a potentially compelling new antiasthma agent. The present application, which is a revised application, is designed to further evaluate the antiinflammatory properties of inhaled A1AS21, to… more
Company: Medtrac Technologies, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: Metered dose inhalers are integral to the treatment of Asthma. Poor compliance to regimens and inapusage of pm medications has been documented in the literature as a serious problem. Data submitted tpharmaceutical companies are questionable without compliance data. Previous MDI… more
Company: SYNVAX Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: … II studies will involve the synthesis of a metabocandidate peptide will be tested against different strains of type A and type B influenza viruses. Ttest the effect of the peptide on normal cellular functions. Pharmacokinetics, cell penetration, andbe conducted. An inhalation… more
Company: Forefront Engineering, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1994 / 1
Abstract: The use of Metered Dose Inhalers (MDI) packaged medication are prevalent in the treatment oflung diseases particularly Asthma. MDI medications have inherent problems with repeatability ofapplication. Spacers and other modified packages have attempted to improve the delivery, but… more
Company: Radiation Safety Engineering, Inc. Agency/Program/Year/Phase: NRC / SBIR / 1994 / 2
Abstract: THE SOLUBILITY OF AIRBORNE RADIONUCLIDES IS AN IMPORTANT PARAMETER IN THE ASSESSMENT OF INHALATION HAZARDS IN THE WORKPLACE AND IN THE INTERPRETATION OF ROUTINE BIOASSAY DATA. SOLUBILITY IS A MAJOR FACTOR IN DETERMINING THE METABOLISM OF THE INHALED ISOTOPES AND DISSOLUTION… more
Company: Inhale Inc Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: INHALE, INC. IS A SMALL BUSINESS DEDICATED TO THE DEVELOPMENT OF MORE PRECISE AND EFFICIENT PULMONARY DRUG DELIVERY SYSTEMS FOR THE DELIVERY OF LOCAL (LOUNG) AND SYSTEMIC THERAPEUTICS. EXISTING AEROSOL DELIVERY SYSTEMS ARE INACCURATE AND REPRODUCIBLE DOSING IS DIFFICULT TO… more
Displaying 101 – 125 of 129 Awards
Narrow Your Search
By Agency
By Year
By Phase
By Program
By State
By Company Ownership
By Company
HELP FOR NARROW YOUR SEARCH

Search Options

There are several categories such as “By Agency”, “By Year”, “By State” etc. Select a checkbox within a category to refine your search results.

Each of your selections is listed in the “Narrow Search Filters” bar. You can uncheck these selections to remove them.


Search for Either Criteria

When you select multiple values within a category, the results will include values that match either of the selections. For example, selecting “2005” and “2007” in the “By Year” category will display results that include either 2005 OR 2007 in the results.


Narrowing the Search Results

You can refine your search results across categories. To narrow down your results, select multiple values across different categories. The results will only include values that match the selections across the categories. For example, selecting “2005” in the “By Year” category and “NASA” in the “By Agency” category will only display the results that contain both “2005” AND “NASA” in the results.