Abstract:With the depletion of fossil fuel reserves, hydrogen-based energy is becoming increasingly significant. Production, purification and compression of hydrogen represent key technical challenges. Hydrogen is most commonly produced from steam methane reformers, by gasification or as a refining or… more
Abstract:DESCRIPTION (provided by applicant): Currently 30 million Americans with elevated cholesterol receive statin therapy, making statins the most prescribed drug class in the U.S. Statin Induction and Neuro-Myopathy (SINM), the balance of potency and safety, is the main clinical management challenge of… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project aims to develop a wireless, needle implantable miniaturized (0.5 x 0.5 x 5 mm) sensor for continuous glucose monitoring, with provisions for internal self-calibration without the need for frequent, external fingerpricking. The proposed… more
Abstract:A composite fatigue damage assessment and risk informed prognosis toolkit will be developed by enhancing and integrating existing solution modules within a probabilistic analysis framework. This tool will for the first time be able to address concurrently both microcracking induced stiffness… more
Abstract:Global Engineering and Materials, Inc. (GEM) along with its team members, Clarkson University and LM Aero, propose to develop a mesh independent probabilistic residual life prediction tool for metallic airframe structures. The deterministic solver of this probabilistic analysis tool will be… more
Abstract:A software toolkit for Abaqus (XSHELL) will be developed for fracture evaluation and load deflection prediction of welded aluminum ship structures subjected to impulsive loading. The mesh independent crack description and fracture energy dissipation will be achieved in XSHELL through the… more
Abstract:A software tool for residual strength and life prediction of advanced hybrid structures will be developed by enhancing and integrating an existing mesh independent 3D X-FEM solid element with a partially bonded cohesive interface element in Abaqus. The tool will be able to model arbitrary location,… more
Abstract:A fully coupled fire-structure interaction module will be developed and implemented within GEM"s Abaqus Fire Interface Simulator Toolkit (AFIST) for fire response prediction in aluminum ship structures. This enhanced AFIST will be able to characterize a 3D complex geometry where its topology is… more
Abstract:A 3D non-linear and rate-dependent constitutive model will be developed and implemented within GEM"s Abaqus Fire Interface Simulator Toolkit (AFIST) to characterize the time-, stress-, and temperature-dependent material response of aluminum alloys. Both the material and geometric… more
Abstract:Global Engineering and Materials, Inc. (GEM) along with its team members, University of Dayton Research Institute (UDRI), Lockheed Martin (LM) Aero, and Sikorsky Aircraft will develop an add-on toolkit for Abaqus with high fidelity prediction of residual strength and life of laminated composite… more
Abstract:Synthesizing a variety of ideas and algorithms from Machine Learning, Kernel methods, Spectral Graph Theory, Diffusion Geometries, Harmonic Analysis and Signal Processing into a single mathematical framework, we propose a data driven processing toolbox capable of generating bi-hierarchical… more
Abstract:DESCRIPTION (provided by applicant): We propose to develop a recombinant subunit vaccine against cutaneous leishmaniasis. This vaccine will incorporate two protein antigens, TSA/TryP and P-4. Both antigens are highly conserved among Leishmania species, arerecognized by T cells of human patients, and… more
Abstract:DESCRIPTION (provided by applicant): Lyme disease, due to infection with the Ixodes tick-transmitted spirochete Borrelia burgdorferi, is the most common vector-borne disease in the United States, with more than 28,000 cases reported annually. The infectioncan remain localized to the skin or… more
Abstract:DESCRIPTION (provided by applicant): The goal of the proposed research is to develop a series of diagnostic assays that will detect specific types of enterotoxigenic Bacteroides fragilis (ETBF). ETBF has been shown to cause diarrhea as well as bowel inflammation and colitis. Experimental evidence… more
Abstract:DESCRIPTION (provided by applicant): Exposure to isocyanate, the essential cross-linker for making polyurethane, is a leading cause of occupational asthma world-wide. Three major types of isocyanate are used commercially, methylene-diphenyl diisocyanate (MDI) and toluene diisocyanate (TDI), or… more
Abstract:A Towed Array Control Module (TACM) will be developed to control the configuration of single and multi-line towed arrays by applying the appropriate force vector at the tail end, while reducing drag. The TACM is a streamlined module with some maneuvering ability of its own that can adjust the… more
Abstract:The SK-LVC Phase II proposal requires the employment of new and evolving technologies in the areas of power generation, autonomous operation and control of both surface and undersea unmanned vehicles, and operation of vehicles across the operational environment continuum from subsurface, surface,… more
Abstract:DESCRIPTION (provided by applicant): Despite the rise of bacterial resistance to antibiotics, the development of new antibiotics is on the decline. Methicillin-resistant Staphococcal aureus infections (MRSA) in the United States has been increasing, causing 19,000 deaths per year in the United… more
Abstract:DESCRIPTION (provided by applicant): Fungal infections continue to be a major cause of morbidity and mortality among HIV- infected patients. At present, there are only three classes of antifungal agents that are suitable for the treatment of AIDS-relatedfungal infections, but these medications are… more
Abstract:An accurate assessment of composite structural performance and proactive component and system life management strategies requires quantitative information on the damage states of the components. Recent advances in infra-red (IR) sensing and data processing technologies have enabled real-time… more
Abstract:Helicopters with articulated rotor blades are subject to the well-known ground resonance where the rotor lag mode interacts, in an unstable fashion, with fuselage roll. To eliminate this ground resonance, both lag dampers and fuselage roll dampers are required. The Sikorsky UH-60 helicopter platform… more
Abstract:ABSTRACT: At present, the common practice in the fighter aircraft industry is to use touch probes as secondary measurement systems to maintain tight machining tolerance control. The current touch-probe inspection process renders the typical milling machine idle while features of the machined part… more
Abstract:ABSTRACT: Aircraft structural components are prone to damage typically assessed by various NDE tools. Damage to the aircraft structural components decreases operational readiness and compromises safety if improperly maintained; however, frequent inspections and maintenance is expensive. CBM+… more
Abstract:To accurately account for effects of environmentally assisted cracking in the overall structural life, quantitative information on the sustained residual stresses needs to be identified. Current methods for residual stress evaluation lack the required level of quantitative accuracy to permit the… more
Abstract:Optoelectronic integrated holds the key to higher performance, reduced mass and radiation-hard space systems. A special need is increased flexibility of phased arrays for communication and detection. Currently RF arrays use ferrite waveguide elements for phase shifting which are both bulky and… more
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