Abstract:Project Summary/Abstract Complete achromatopsia is an autosomal recessive inherited congenital disorder of retinal cone photoreceptors. Patients with complete achromatopsia experience extreme light sensitivity and daytime blindness, and best visual acuityunder non-bright light conditions is usually… more
Abstract:Project involves development of new flexible FR polyurethane (PU)insulation foams through a non-toxic environmentally friendly composite approach. Foams have bound-in polymeric phosphonate FRs, with added synergists and smoke suppressants. Such foams will not leach FR. Foams have fine cell… more
Abstract:A Space Communications and Navigation (SCaN) flight experiment will demonstrate Next Generation Navigation Techniques and Advance SDR/STRS Communications Technology to TRL-7. Scintillation-hardening techniques will be applied to an open-source waveform ported to the SCaN platform. This will result… more
Abstract:A launch vehicle and its launch facilities are subjected to intense acoustic loads generated by the vehicle's propulsion system. The vehicle, its payload, and facilities must be designed to withstand these loads to ensure mission safety and success. Accurately accounting for the acoustic… more
Abstract:The U.S. is suffering from a $10billion and growing trade offset in fisheries products, with the majority of these products coming from farmed sources abroad. Several limiting factors exist that are inhibiting the growth of aquaculture in developed nations like the U.S., one of which is the… more
Abstract:Current status/problem: Wind loading calculations for structures are currently performed according to the ASCE (American Society of Civil Engineers) 7 Standard. The values in this standard were calculated from simplified models that do not necessarily take into account relevant characteristics such… more
Abstract:The innovation is a System and Application Programming Interface, data services and device control, coupling geospatial visualization and database technologies with mobile sensor networks. A product line will be developed, beginning with a map-based streaming media and moving objects video console.… more
Abstract:ABSTRACT: Under the first phase of the program, Plasmonics Inc. and Sandia National Laboratories investigated a range of surfaces that yield non-Lambertian emission profiles in the thermal infrared. The second phase of this program will further maturate the designs developed in the first phase of… more
Abstract:Feasibility of the microbolometer detectors using novel thin film materials was proven in Phase I. Phase II will continue these efforts by producing packaged sensors that are designed to function in PFx systems for persistent ISR applications. In order to provide a low unit cost, high sensitivity,… more
Abstract:DESCRIPTION (provided by applicant): Acute pesticide poisoning remains a vast health problem in the developed and developing world. Domestically, a 2004 study estimates that 18 of every 100,000 US agricultural workers suffer from acute pesticide poisoningand a 2002 study of California air found… more
Abstract:DESCRIPTION (provided by applicant): Sepsis is the tenth-leading cause of death in the United States and the second-leading cause of death in the intensive care unit (ICU). Sepsis kills over 215,000 Americans each year - more than breast cancer, lung cancer, and prostate cancer combined. Rapid… more
Abstract:DESCRIPTION (provided by applicant): The majority of multiple myeloma (MM) patients will initially respond to standard chemotherapy. However, eventually relapse of the disease, associated with a multi-drug resistant phenotype, contributes to poor clinicaloutcomes. Modulation Therapeutics is… more
Abstract:This Small Business Innovation Research Phase I project will further develop a new software package for automatic dimensional analysis of nanomaterials from electron microscopy images. The difficult task of manual dimensional analysis of nanomaterials is a significant barrier to the success of the… more
Abstract:DESCRIPTION (provided by applicant): According to the American Cancer Society, half of all men and one-third of all women in the United States will develop cancer in their lifetime. While chemotherapy has dramatically improved the survival rate of cancer patients, it comes at the cost of severe… more
Abstract:DESCRIPTION (provided by applicant): Preeclampsia, a hypertensive disorder of pregnancy, is a leading cause of maternal and neonatal morbidity and mortality around the world, responsible for approximately 76,000 maternal and 500,000 infant deaths per year.As a heterogeneous and poorly understood… more
Abstract:DESCRIPTION (provided by applicant): Poor medication adherence has a significant negative impact on patients, clinical study outcomes, and the healthcare system in general. As much as 25% of all healthcare costs could be avoided if patients reliably took their prescribed medications. Medication… more
Abstract:The project team is developing a prototype of a web-based gaming intervention for students in kindergarten to grade 2 to learn standard-based concepts in science, technology, engineering, and math. The games will include engaging and interactive simulations, investigations, stories and videos, as… more
Abstract:This Small Business Innovation Research Phase I project seeks to demonstrate ultra high efficiency quantum dot light-emitting diodes (QD-LEDs) using a top-emitting structure and micro-lens array for display applications. Two key challenges will be addressed. First, a novel top-emitting structure… more
Abstract:DESCRIPTION (provided by applicant): Lung cancer is the leading cause of cancer deaths worldwide. The high mortality is in part due to the lack of good tests for early detection and treatment. Our technology diagnoses the presence of cancer via analysis ofthe specific fingerprint of volatile organic… more
Abstract:ABSTRACT: GameSim is proposing the development of a proof-of-concept Tactical Training Rehearsal Environment (TTRE) built upon Prepar3D, a commercial off-the-shelf (COTS), visual simulation platform. Lockheed Martin, the developer of Prepar3D and the prime contractor for the F-22 and F-35, will be… more
Abstract:Forest understory is an under-utilized woody biomass totaling about 300 million dry tons in the southeastern U.S. alone. One percent recovery of this potential source of energy amounts to about 25 billion Btu per year. Traditional forest management practices require controlled understory burning. To… more
Abstract:This proposal details inventive ways for developing affordable reinforced polymer structures with embedded electrical interfaces. Recent developments in the use of advanced composites for rapidly fabricating cylindrical missile shells have shown that it is possible to incorporate complex circuitry… more
Abstract:Onsite wastewater systems are a significant source of nutrient loading to the environment and there is a demand for technologies that remove nutrients at the source. Most desired are passive, low cost systems that can consistently remove ninety percent or greater nitrogen while having low energy… more
Abstract:Unmanned Aerial System (UAS) operation represents a stressful, cognitively challenging domain where operators are routinely subjected to both occupational and combat stressors and performance failures can have catastrophic effects. Effective performance in such conditions has many dimensions,… more
Abstract:PCP Ammunition Company will deliver a family of Lightweight Advanced Polymer Sub-Sonic Ammunition. We will do this by adapting our current family of calibers by decreasing the internal volume and shape of the case to match the optimal performance requirements of the cartridges. This will result in… more
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