Company:Genetic ID NAAgency/Program/Year/Phase:NSF / SBIR / 2003 / 1
Abstract:This Small Business Innovation Research (SBIR) Phase I project is to develop a fluidic wave guide biosensor that employs unique physical and structural features to measure biological pathogens. Preliminary research indicates that this diagnostic technology promises to achieve a combination of speed… more
Abstract:NON-TECHNICAL SUMMARY: Since the Food and Drug Administration announced in 1999 that foods containing soy protein may reduce the risk of coronary heart disease, commercial food companies have been looking for soy foods to meet customer demand for more healthful, convenient food. Development of… more
Abstract:DESCRIPTION (provided by investigator): The medication dispensing and monitoring system, MD 2, has been shown in preliminary studies to support a medication compliance rate of 98.5% The MD 2 was developed by Interactive Medical Developments LC to address issues of medicine non-compliance and the… more
Abstract:DESCRIPTION (provided by applicant): Age-related muscle loss is a major public health issue affecting over 30 million Americans, with no viable treatments available to stem about an 8% loss in muscle mass every decade. Preliminary studies with beta-hydroxy-beta-methylbutyrate, arginine, and lysine… more
Abstract:DESCRIPTION (provided by applicant): Of the four million cases of trauma cases each year that will require hospitalization, 200,000 will be classified as severe trauma. During the hospital stay, malnutrition is a major complication in about 50% of the patient population. The result is muscle… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project proposes to develop sex pheromone-based techniques for monitoring, mass trapping, and mating disruption of the soybean aphid. Since its first appearance in North America, infestations of the newly invasive soybean aphid, Aphis glycines… more
Abstract:This Small Business Innovation Research Phase I project, will develop a liquid lens for nanomachining materials with pulsed laser beams. The project team will design and fabricate a liquid lens capable of producing laser beam spot sizes on the order of nanometers (20-100 nm) through its nonlinear… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project seeks to develop a homologous recombination or gene targeting system for plants. Gene targeting offers great promise for harnessing the biosynthetic capacity of plants to produce compounds of commercial value. A major limitation in… more
Abstract:LIDAR (laser radar) is used for oceanographic research, and emits a short light pulse whose return echoes are digitized and analyzed to determine the composition and location of underwater objects. This requires a digitizer with high sampling speed, wide bandwidth commensurate with the pulse width,… more
Abstract:Shrouded-fans play a key role in the U.S. Army's transportation systems. A preliminary design tool capable of simulating the flow field in different flight conditions for predicting the shroud and fan performance can significantly reduce design costs. Thisproposal offers a computational tool that… more
Abstract:Viscous analysis is vital for a complete understanding of missle and UAV aerodynamic properties. This proposal offers a technique for generating grids suitable for viscous analysis on complex configurations.The principle idea is to divide the region closest to the body into a sequance of… more
Abstract:DESCRIPTION (provided by applicant):
We propose to develop a novel cancer therapy using allosteric reagents for concentrating a prodrug around a target cancer cell. Our aptamer-based design, called a CLAMP (cis-linked aptamers for medical or microanalytical procedures), is a nucleic acid with two… more
Abstract:DESCRIPTION (provided by applicant):
Detection and treatment of cancer can be greatly facilitated by noninvasive in vivo imaging techniques. In vivo imaging methods are most effective if they can be seamlessly tied to therapies. We propose to develop a novel imaging system using allosteric… more
Abstract:Rapid tests for microbial detection in food processing on the market today provide information on the presence or absence of specific pathogens after an enrichment process of 24 to 48 hours. Our method will utilize immunomagnetic separation after brief enrichment (
Abstract:DESCRIPTION (provided by applicant): Rapid detection of biological warfare agents is one of the first lines of defense against bioterrorism. The development of multiplexed sensors capable of detecting any known biological warfare agent will be essential to rapidly implement measures to protect the… more
Abstract:"Giant magnetostrictive materials, specifically the alloys of TERFENOL-D possess a high energy density that enables compact, high power, broad-band sources and similar, high authority actuators for use in several different military and commercialapplications. Current manufacturing techniques,… more
Abstract:"Metallic sheathed magnetostrictive wires (MSMW) will be developed for use in fiber reinforced composite structures. These magnetostrictive wires will be based on rare earth intermetallics such as the "giant" magnetostrictive material TERFENOL-D. Thesmart material characteristics of the… more
Abstract:"Thin film photovoltaic (PV) modules fabricated on polymer substrates have a number of very attractive features for space use. Flexible a-Si modules: 1) have shown minimum degradation due to radiation; 2) can have low fabrication costs; 3) havedemonstrated very high power to weight ratios; 4) have… more
Abstract:"Demand for electrical power in portable and temporary installations continues to increase, which adds significant logistical burden in terms of weight, maintenance, and fuel demand. Power demands include command & control operations, medical operations,lighting, chemical/biological filtering, and… more
Abstract:DESCRIPTION (provided by applicant) New Leaf Interactive Media, working with the Hazardous Materials Training and Research Institute at Kirkwood Community College will, over a 2-year period, use cutting-edge technologies to produce and pilot-test three (3) DVD videos that are multi-platform,… more
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