Abstract:Development of novel boronated compounds and use of epithermal neutrons has now generated much interest in 10B-boron capture neutron therapy of different tumors. However, no suitable methods exist that allow investigation of their pharmacokinetics in human subjects or in vivo measurement of the… more
Abstract:THE RESULT OF THIS PHASE I EFFORT WILL BE A DETAILED PLAN TO SIGNIFICANTLY INCREASE THE SPEED AND, HENCE, THE INTERACTIVITY OF ANALYZE, AN ALREADY USEFUL MEDICAL IMAGE ANALYSIS SYSTEM. ANALYZE IS A SOFTWARE SYSTEM FOR THE ANALYSIS OF MEDICAL IMAGES, DEVELOPED AT MAYO FOUNDATION'S BIOTECHNOLOGY… more
Abstract:X-ray computed tomography (CT) is widely used in defense, aerospace, and industrial applications. CT provides flaw detection, density measurement, accurate dimensions, morphology, assembly verification, material property analysis, and other vauable information. However, a major limitation of CT has… more
Abstract:We propose to develop in this Phase I SBIR a technique to produce high-energy, multi-aspect radiographic images in near real-time, using a conventional real time radiography (RTR) system. This technique, stereo-pair imaging, will allow three-dimensional analysis of RTR images by producing two views,… more
Abstract:We will develop a new construction method for receiver coils for magnetic resonance imaging (MRI) of the human breast. These coils will be custom-shaped to individual patients in a quick, economical, and comfortable manner. Since each structure fits the individual patient closely, the coil system… more
Abstract:Laser chemical vapor deposition (LCVD) silicon nitride fiber growth is proposed, to make fibers which have the strength and oxidative stability required for advanced high temperature structural applications. This method has been demonstrated to yield continuous, high strength fibers of materials… more
Abstract:Interactive multimedia materials teaching safer sexual practices will be developed to motivate, educate, and prevent relapse in young heterosexual adults. Target group members will include sexually active, 18 to 29 year old women and men, with and without sexually transmitted diseases, either… more
Abstract:A NEW TYPE OF RANGE EXTENT SIMULATOR HAS BEEN MADE POSSIBLE THROUGH RECENT DEVELOPMENTS IN THE EMERGING MICROELECTRONIC TECHNOLOGY OF ACOUSTIC CHARGE TRANSPORT (ACT). THIS TECHNOLOGY, DEVELOPED JOINTLY BY DARPA AND THE U.S. AIR FORCE, HAS ENABLED THE IMPLEMENTATION OF DIGITALLY PROGRAMMABLE ANALOG… more
Abstract:The present system of communication between KC-135/KC-10 tanker aircraft and receptacle-equipped receiver aircraft calls for communication based on aircraft lights. The Air Force requires a system for undetectable verbal communication between tanker and receiver from a range of 1500 meters to point… more
Abstract:The goal is to publish an assessment battery for normal and disabled children from 2 1/2 to 7 years of age and to make it available to clinicians, educators, and researchers. The battery will incorporate three innovative features that are important for effective assessment of children's cognitive… more
Abstract:Cyclosporin brought the field of transplantation science into the mainstream of medicine. Unfortunately, long-term survival and quality of life for transplant recipients are still severely diminished. Recently, the natural products, FK-506 and rapamycin, have proven in studies to be safe, more… more
Abstract:GLOBAL INFORMATION SYSTEMS TECHNOLOGY, INC. PROPOSES TO DEVELOP AN INTELLIGENT TUTORING SYSTEM (ITS) ARCHITECTURE THAT IS FLEXIBLE, MODULARLY STRUCTURED TO ALLOW FOR FUTURE EVOLUTION, AND WHICH CAN BE USED IN A FAMILY OF TACTICAL WEAPON SYSTEMS IN EMBEDDED TRAINING OPERATIONS. IN PARTICULAR, WE… more
Abstract:THE AIR FORCE HAS BEEN USING COMPUTER-BASED TRAINING FOR MORE THAN 20 YEARS, YET IT STILL CONFRONTS MANY OF THE SAME BASIC PROBLEMS: SUBJECT MATTER EXPERTS ARE USUALLY NOT INSTRUCTIONAL DESIGNERS, INSTRUCTIONAL DESIGNERS ARE USUALLY NOT PROGRAMMERS, CBT COURSEWARE IS EXPENSIVE TO DEVELOP (TYPICALLY… more
Abstract:IT IS PLANNED TO DEVELOP CD-AGING, A CD-ROM CONTAINING DATABASES USEFUL TO RESEARCHERS ON HUMAN AGING. THE PROJECTWILL INVOLVE SELECTING AND REFORMATTING THE DATABASES, AND EMBEDDING THEM IN A PC ENVIRONMENT THAT WILL SUPPORT EASY ACCESS TO THE DATA FOR VIEWING AND FOR PROCESSING BY FAMILIAR… more
Abstract:THIS GRANT SEEKS TO DEMONSTRATE THE FEASIBILITY OF PROVIDING AN INTERACTIVE MULTI-MEDIA PRESENTATION METHODOLOGY FOR CANCER PREVENTION INFORMATION THAT CAN INFLUENCE CHANGES IN BEHAVIOR. WE PLAN TO EMPLOY NEWLY DEVELOPED TECHNOLOGIES TO ENHANCE THE PRESENTATION OF INFORMATION FROM SOMETHING… more
Abstract:In this project we will build a CD-ROM database containing images of highly verified chromatograms of chemicals, especially those pertinent to cancer/health research. Suitable indexing of these images will make retrieval rapid, and we will research ways to enable CD-ROM users to download these data… more
Abstract:Patient clinical data, which is of great necessity and utility in providing the best and most cost-effective patient care to a given individual as well as valuable for medical treatment effectiveness programs that can benefit our society as a whole, are currently very difficult to obtain. Clinical… more
Abstract:Online distribution of electronic cancer information provides rapid distribution of the most up-to-date, life-saving information. The National Cancer Institute (NCI) has recognized these benefits and developed numerous electronic databases that are distributed through various channels. Nevertheless,… more
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