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Displaying 18876 – 18900 of 20119 Awards
Company: Biogen Research Corp Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: POLYMORPHIC CELL-SURFACE MOLECULES ENCODED BY THE MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) OF VERTEBRATES ARE RESPONSIBLE FOR INITIATING A NUMBER OF PHYSIOLOGICAL RESPONSES WHEN THESE ANTIGENS ARE RECOGNIZED AS "NONSELF" BY THE IMMUNE SYSTEM. THE REJECTION OF DONOR TISSUE GRAFTS BY RECIPIENTS WHOSE… more
Company: Biogen Research Corp Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: A MODEL SYSTEM FOR PRODUCTION OF RECOMBINANT PROTEINS IN MILK USING MICE WILL BE DEVELOPED IN PHASE I. THIS WILL ESTABLISH THAT IT IS POSSIBLE TO PRODUCE NOVEL PROTEINS IN MILK FROM MAMMARY TISSUES. A PROMOTER SPECIFIC FOR MAMMARY CELLS WILL BE USED TO DIRECT THE EXPRESSION OF A TEST PROTEIN THAT IS… more
Company: Bioremediation Consulting, Agency/Program/Year/Phase: EPA / SBIR / 1987 / 1
Abstract: COAL TAR IS A BY-PRODUCT OF THE COAL GASIFICATION PROCESS USED WIDELY BETWEEN 1820 AND 1950 TO PRODUCE A NATURAL GAS SUBSTITUTE. DURING THAT TIME, BILLIONS OF GALLONS OF TAR WERE PRODUCED AT MORE THAN 1500 GAS MANUFACTURING FACILITIESLOCATED THROUGHOUT THE U.S. A LARGE PORTION OF THIS WASTE TAR… more
Company: BIOTEK, INC. Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP SUSTAINED-ACTION, INJECTABLE, BIODEGRADABLE, NALTREXONE MICROCAPSULES TO MAINTAIN PLASMA LEVELS AT 2 NG/ML FOR AT LEAST 1 MONTH. PHASE I SUPPORT IS SOUGHT FOR A 6-MONTH PERIOD TO CONDUCT PRELIMINARY FEASIBILITY STUDIES. DURING PHASE I, NALTREXONE… more
Company: BIOTEK, INC. Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: THE OVERALL OBJECTIVE OF THE PROJECT IS TO DEVELOP MICROENCAPSULATION PROCEDURES AND FORMULATIONS FOR STABILIZING THE PROPERTIES OF CHEMICALS THAT ARE UNSTABLE UNDER NORMAL ENVIRONMENTAL CONDITIONS. THE STABLE MICROCAPSULES WILL BE MIXED WITH RODENT FEED, AND THE CHRONIC TOXICITY OF THE CHEMICALS… more
Company: BIOTEK, INC. Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: THE OVERALL OBJECTIVE OF THE 6-MONTH PROJECT IS TO DEVELOP ASUSTAINED-RELEASE FLUORIDE DENTIFRICE FORMULATION BASED ON MICROCAPSULES WITH A DURATION OF 12 TO 24 HOURS. IN PHASE I, SODIUM FLUORIDE MICROCAPSULES WILL BE PREPARED AND CHARACTERIZED FOR NAF CONTENT, GEOMETRY, AND FLUORIDE-RELEASE PROFILE… more
Company: BIOTEK, INC. Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: N/A
Company: BIOTEK, INC. Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: N/A
Company: Cambridge Analytical Assoc Inc Agency/Program/Year/Phase: NSF / SBIR / 1987 / 2
Abstract: LOW MOLECULAR WEIGHT CHLORINATED HYDROCARBONS ARE WIDESPREADENVIRONMENTAL CONTAMINANTS AND ARE OF CONCERN BECAUSE OF THEIR TOXIC AND CARCINOGENIC PROPERTIES. THEY ARE PERSISTENT IN SOILS AND GROUNDWATER, RESIST DEGRADATION IN BIOLOGICAL WASTEWATER TREATMENT SYSTEMS, AND ARE EXPENSIVE TO REMOVE FROM… more
Company: Cambridge Analytical Assoc Inc Agency/Program/Year/Phase: EPA / SBIR / 1987 / 2
Abstract: COAL TAR IS A BY-PRODUCT OF THE COAL GASIFICATION PROCESS USED BETWEEN 1880 AND 1950 TO PRODUCE A NATURAL GAS SUBSTITUTE. IT IS ESTIMATED THAT SEVERAL BILLION GALLONS OF THIS MATERIAL WERE LAND-DISPOSED AT OVER 1500 SITES IN THE UNITED STATES. THE TAR CONTAINS SEVENTEEN POLYNUCLEAR AROMATIC… more
Company: Cambridge Analytical Assoc Inc Agency/Program/Year/Phase: NSF / SBIR / 1987 / 1
Abstract: COAL TAR IS A BY-PRODUCT OF THE COAL GASIFICATION PROCESS USED BETWEEN 1820 AND 1950 TO PRODUCE A NATURAL GAS SUBSTITUTE. IT IS ESTIMATED THAT SEVERAL BILLION GALLONS OF THIS MATERIAL WERE LAND-DISPOSED AT OVER 1500 SITES IN THE U.S. THE TAR CONTAINS POLYNUCLEAR AROMATIC HYDROCARBONS (PAH) WHICH… more
Company: Cambridge Medical Diagnostics Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: RADIOIMMUNOASSAYS (RIAS) REPRESENT THE STANDARD METHODOLOGY FOR THE MEASUREMENT OF PARATHYROID HORMONE (PTH). HOWEVER, THERE ARE A NUMBER OF LIMITATIONS ASSOCIATED WITH THE MEASUREMENT OF PTH BY THIS TECHNIQUE. MOST IMMUNOASSYS ARE INSENSITIVE AND, THEREFORE, CANNOT DETECT CIRCULATING LEVELSOF… more
Company: CAMBRIDGE RESEARCH AND INSTRUMENTATION Agency/Program/Year/Phase: NASA / SBIR / 1987 / 2
Abstract: THE PURPOSE OF OUR RESEARCH PROGRAM IS TO DEVELOP A HELIUM-COOLED ABSOLUTE RADIOMETER SUITABLE FOR WIDE-BAND MEASUREMENTS OF THE EARTH'S RADIATION AT AN ANGULAR RESOLUTION TWO ORDERS OF MAGNITUDE BETTER THAN ACHIEVED WITHTHE EXISTING ERBE RADIOMETERS. WE HAVE CONSTRUCTED AND CHARACTERIZED A… more
Company: CAMBRIDGE RESEARCH AND INSTRUMENTATION Agency/Program/Year/Phase: DOD / SBIR / 1987 / 1
Abstract: MACROSCOPIC ELECTRIC FIELDS PLAY A CENTRAL ROLE IN THE PROCESSES OF RECONNECTION AND PARTICLE ACCELERATION THAT FIGURE PROMINENTLY IN SOLAR-TERRESTRIAL PHYSICS STUDIES OF FLARES AND FILAMENT ERUPTIONS. DETECTION OF THESE FIELDS AND MEASURMENT OF THEIR MAGNITUDE, ORIENTATION, SPATIAL DISTRIBUTION,… more
Company: CANDELA CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1987 / 2
Abstract: BILIARY STONE DISEASE AFFECTS OVER 16 MILLION PEOPLE IN THE UNITED STATES. APPROXIMATELY 1 MILLION NEW CASES OF CHOLELTHIASIS DEVELOP EACH YEAR, AND SURGICAL INTERVENTION WAS REQUIRED IN 554,000 PROCEDURES IN 1984, A 3% INCREASE FROM 1983. THE AVERAGE LENGTH OF HOSPITALIZATION FOR THESE PATIENTS IS… more
Company: CANDELA CORPORATION Agency/Program/Year/Phase: NASA / SBIR / 1987 / 1
Abstract: HETERODYNE HOLOGRAPHIC INTERFEROMETRY AND TIME-AVERAGE HOLOGRAPHY WITH A FREQUENCY SHIFTED BEAM HAVE BEEN PROPOSED FOR USE IN THE MEASUREMENT AND VISUALIZATION OF INTERNAL TRANSONIC FLOWS. A LONG PULSE FLASHLAMP EXCITED DYE LASER HAS BEEN SHOWN TO PRODUCE OVER 50 MILLIJOULES PER PULSE FOR OVER 50… more
Company: CANDELA CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: N/A
Company: Cape Cod Research Agency/Program/Year/Phase: NASA / SBIR / 1987 / 1
Abstract: AN EXPERIMENTAL PROGRAM IS PROPOSED TO EXPLORE THE FEASIBILITY OF USING SOLID FLEXIBLE FILMS FOR THE ELECTRICALMODULATION OF CONDUCTIVE HEAT TRANSFER SO THAT A VARIABLE THERMAL SWITCH MIGHT BE DEVELOPED CAPABLE OF CONTROLLING ENERGY FLOW TO OR FROM AN ADVANCED SPACECRAFT COMPONENT.
Company: Cape Cod Research Agency/Program/Year/Phase: NSF / SBIR / 1987 / 1
Abstract: LUBRICANT QUALITY SIGNIFICANTLY INFLUENCES THE RELIABILITY, LIFE AND ENERGY EFFICIENCY OF VIRTUALLY ALL SYSTEMS. HOWEVER, THERE EXISTS NO RELIABLE, ON-LINE PERFORMANCE MONITORING TECHNIQUE FOR REDUCING UNSCHEDULED DOWNTIME AND IMPROVING PRODUCTIVITY. THIS RESEARCH STUDIES THE FEASIBILITY OF… more
Company: Cape Cod Research Agency/Program/Year/Phase: DOD / SBIR / 1987 / 1
Abstract: N/A
Company: CASTLE TECHNOLOGY CORP. Agency/Program/Year/Phase: DOD / SBIR / 1987 / 2
Abstract: NOVEL BATTERY CONFIGURATIONS WITH MICROELECTRODES ARE DESCRIBED. THESE BATTERIES SHOULD EXHIBIT VERY LOW INTERNAL CELL RESISTANCE, GREATLY REDUCED CONCENTRATION POLARIZATION EASE OF ACTIVATION IN THE RESERVE MODE AND EXTREMELY RAPID DISCHARGE. THEORETICAL CONSIDERATIONS PROVIDE THE BASIS FOR… more
Company: CASTLE TECHNOLOGY CORP. Agency/Program/Year/Phase: NSF / SBIR / 1987 / 1
Abstract: NEW METHODS OF CRITICALLY EVALUATING THE POTENTIAL RISKS OF EMERGING MATERIALS AND TECHNOLOGIES ARE NEEDED TO CONTROL THE SOURCES OF ENVIRONMENTAL HAZARDS AT THE POINTS OF ORIGIN. RECYCLE AND REPROCESSING OPTIONS MINIMIZE THE ENVIRONMENTAL EXPOSURE TO POTENTIALLY HARMFUL MATERIALS BY OFFERING AN… more
Company: CBR LABORATORIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: DURING THE NEXT YEAR, OVER 4 MILLION UNITS OF PLATELETS WILL BE TRANSFUSED IN THE UNITED STATES FOR A VARIETY OF MEDICAL REASONS. IN SPITE OF THE REMARKABLE BODY OF KNOWLEDGE ABOUT PLATELET PHYSIOLOGY AND BIOCHEMISTRY, EFFICACY OF THIS BLOOD PRODUCT IN CORRECTING BLEEDING PROBLEMS IS USUALLY… more
Company: CBR LABORATORIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: HEMOPHILIA B IS A SEVERE BLEEDING DISORDER CHARACTERIZED BY A FUNCTIONAL DEFICIENCY IN THE BLOOD COAGULATION PROTEIN FACTOR IX (OR CHRISTMAS FACTOR). THERAPY FOR BLEEDING EPISODES IN THESE PATIENTS REQUIRES THE INTRAVENOUS REPLACEMENT OF FACTOR IX GIVEN AS FRESH FROZEN PLASMA OR WITH COMMERCIALLY… more
Company: CENTRA Technology, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1987 / 1
Abstract: N/A
Displaying 18876 – 18900 of 20119 Awards
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