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Displaying 6651 – 6675 of 7760 Awards
Company: Manufacturing And Technology Conversion Int'l, Inc Agency/Program/Year/Phase: DOE / SBIR / 1991 / 1
Abstract: SYNCRUDE OIL OBTAINED BY RETORTING OIL SHALE REPRESENTS A POTENTIAL SOURCE OF FUEL AND CHEMICAL FEEDSTOCK. THE EXTENT OF TOTAL U.S. RESOURCES GREATER THAN 15 GALLONS OF SYNCRUDE OIL PER TON OF OIL SHALE IS ESTIMATED TO BE 2.5 TRILLION BBL. THE STATE-OF-THE-ART OIL SHALE RETORTING TECHNOLOGY IS NOT… more
Company: MARTEK BIOSCIENCE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: THE (14)C-TRIOLEIN BREATH TEST IS A POPLAR ALTERNATIVE TO THE CLASSICAL 72-HOUR FECAL FAT COLLECTION FOR MEASURING FAT MALABSORPTION BECAUSE OF ITS SIMPLICITY AND THE RAPIDITY WITH WHICH A DIAGNOSIS CAN BE MADE. HOWEVER, BECAUSE OF THE CONCERN FOR THE LONG-TERM EFFECTS OF LOW-LEVEL RADIATION… more
Company: MARTEK BIOSCIENCE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: DOCOSAHEXAENOIC ACID (DHA) IS THE MOST ABUNDANT LONG-CHAIN POLYUNSATURATED FATTY ACID IN THE GREY MATTER OF THE BRAIN. HUMANS CAN CONVERT DIETARY LINOLENIC ACID INTO DHA, BUT THIS PROCESS IS SLOW. CONSEQUENTLY, AT THE TIME OF THE MOSTRAPID BRAIN DEVELOPMENT IN THE FIRST FEW MONTHS OF LIFE, THERE IS… more
Company: MARTEK BIOSCIENCE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: DEUTERATED OR 13-CARBON-LABELED L-LACTATE IS WIDELY USED IN MEDICAL DIAGNOSIS AND CLINICAL RESEARCH. THE STABLE, ISOTOPICALLY LABELED LACTATE IS NONTOXIC, AND NO ETHICAL OR DISPOSAL PROBLEMS DETER ITS USE IN HUMAN SUBJECTS. BY VIRTUE OF THEIR ABILITY TO GROW IN D2O INSTEAD OF H2O AND TOUSE (13)CO2… more
Company: MARTEK BIOSCIENCE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: THE PRESENCE OF ENRICHED STABLE ISOTOPE CONTENTS IN PROTEINS, COUPLED WITH SOPHISTICATED TWO- AND THREE-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE TECHNIQUES, ENABLES A RAPID AND EASY DETERMINATION OF AMINO ACID SEQUENCE AND PROTEIN STRUCTURE. GLYCEROL IS OFTEN USED AS THE SOLE CARBON SOURCE FOR THE… more
Company: MARTEK BIOSCIENCE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: THE OVERALL GOAL OF THIS PROJECT IS TO MANUFACTURE AN OIL DERIVED FROM ALGAE WHICH IS ENRICHED IN OMEGA-3 POLYUNSATURATED FATTY ACIDS. PRELIMINARY DATA HAVE SHOWN THERE IS A DIATOM WHICH PRODUCES A NON-MEMBRANE ASSOCIATED TRIGLYCERIDE WITH A HIGH CONTENT OF EPA BUT LOW CONTENTS OF OTHER… more
Company: MARTEK BIOSCIENCE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: BETA-CAROTENE (PROVITAMIN A) HAS RECENTLY BEEN SHOWN TO BE AN EFFECTIVE CHEMOTHERAPEUTIC AGENT IN THE TREATMENT AND PREVENTION OF CANCER. MOREOVER, CAROTENES PRODUCED BIOSYNTHETICALLY (CONTAINING 9-CIS ISOMERS) APPEAR TO BE A MORE EFFECTIVE ANTITUMOR AGENTS THAN THOSE PRESENTLY MANUFACTURED… more
Company: MARTEK BIOSCIENCE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: N/A
Company: MCCREARY RESEARCH, INC. Agency/Program/Year/Phase: DOC / SBIR / 1991 / 1
Abstract: THE DISSEMINATION OF TIMELY WEATHER DATA IS BECOMING INCREASINGLY IMPORTANT AS THE POPULATION DENSITY OF THE UNITED STATES INCREASES. AS THE SOLE GOVERNMENT OPERATED RADIO SYSTEM PROVIDING DIRECT WARNINGS TO PRIVATE HOMES, THENOAA WEATHER RADIO (NWR) SYSTEM IS CRITICAL FOR DISSEMINATING NATURAL… more
Company: MEDIMMUNE, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: NUMEROUS EXPRESSION SYSTEMS EXIST FOR THE PRODUCTION OF PROTEINS IN BOTH PROKARYOTIC AND EUKARYOTIC CELLS. EACH SYSTEM HAS ITS OWN SET OF ADVANTAGES AS WELL AS SHORTCOMINGS. THE NEED REMAINS FOR A MAMMALIAN CELL EXPRESSION SYSTEM THAT CAN ACHIEVE HIGH-LEVEL TARGET GENE EXPRESSION, CORRECTLY PROCESS… more
Company: Mentor Technologies, Inc. Agency/Program/Year/Phase: DOC / SBIR / 1991 / 1
Abstract: THREE ASPECTS OF CLIMATE CHANGE INVOLVING VERY HIGH TROPICAL CLOUDS ARE: (1) WHETHER CHANGES IN HIGH CLOUD PARAMETERS LEAD TO POSITIVE OR NEGATIVE FEEDBACK IN CO2 EFFECTS ON CLIMATIC TEMPERATURE CHANGES; (2) DO CHANGES IN THE HEIGHTS OF CLOUD TOPS AND CLOUD AMOUNT, OR CLOUDS WHICH REACH TO THE… more
Company: Mentor Technologies, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: THE OBJECTIVE IS TO DEVELOP A REMOTE VIDEO SENSOR UNIT WHICH WILL BE USED WITH A TRACKING SYSTEM. MTI HAS ALREADY DESIGNED AND HAS CONSTRUCTED A VIDEO SURVEILLANCE UNIT PROTOTYPE FOR A COMPETELY AUTOMATED MULTIPLE TARGET/MULTIPLE SENSOR TRACKING SYSTEM, UNDER CONTRACT TO THE U.S. ARMY, WHITE SANDS… more
Company: Mentor Technologies, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: VLSI (VERY LARGE SCALE INTEGRATION) TECHNOLOGY HAS BEEN DEVELOPED TO THE POINT WHERE SPECIAL PURPOSE PROCESSORS MAY BE CONCATENATED TO FORM COMPACT SUPERCOMPUTERS WITH FAR GREATER THROUGHPUT RATES THAN UNI-PROCESSOR MACHINES. THESE NEW MASSIVELY PARALLEL COMPUTERS PROMISE TO SOLVE THE ARMY'S EVER… more
Company: Micro-marketing Systems Inc Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: THE PREVENTION OF DECUBITUS ULCERS (DU) REQUIRES CARE BY AIDES WHO MAY LIMITED KNOWLEDGE OR EXPERIENCE WITH THE CONDITION THEY ARE SEEKING TO PREVENT. HELPSKIN IS AN INFORMATION RESOURCE/DIRECTORY DESIGNED TO INCREASE NURSING CAREGIVERS KNOWLEDGE OF THE PREVENTION OF DU. IT IS DESIGNED FOR LOCATION… more
Company: Molecular Oncology Inc Agency/Program/Year/Phase: DOD / SBIR / 1991 / 2
Abstract: USE OF SYNTHETIC PEPTIDES, COMPRISING BOTH B AND T CELL DETERMINANTS, IS BEING CONSIDERED A VIABLE APPROACH TO VACCINE DEVELOPMENT. WE WILL EXPLORE THE SUITABILITY OF THIS STRATEGY EMPLOYING RIFT VALLEY FEVER VIRUS (RVFV) AS THE STUDY MODEL. THE IMMUNOGENICITY OF SYNTHETIC PEPTIDES REPRESENTING… more
Company: Molecular Oncology Inc Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: FOR MANY TYPES OF CANCER, PATIENT MORBIDITY-AND ULTIMATELY MORTALITY-IS DUE TO THE DEVELOPMENT OF METASTATIC LESIONS. EXPERIMENTAL EVIDENCE SUGGESTS THAT TUMORS CAN INHERENTLY DIFFER IN THEIR ABILITY TO FORM METASTASIS. AS YET THERE ISNO AVAILABLE TEST TO DETERMINE IF PARTICULAR HUMAN TUMORS ARE OF… more
Company: Molecular Oncology Inc Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: METASTASIS FROM TUMORS OF EPITHELIAL ORIGIN SUCH AS THE LUNG, COLON, BREAST, AND PROSTATE CONSTITUTE THE CAUSE OF THE MAJORITY OF CANCER RELATED DEATHS. THERE EXIST FEW EXPERIMENTAL SYSTEMS SUITABLE FOR THE TESTING OF ANTI-METASTATIC AGENTS ON HUMAN EPITHELIAL TUMORS. WHILE MANY CELL LINES FORM… more
Company: Molecular Oncology Inc Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: THE DEGRADATION OF THE COLLAGEN TYPE IV NETWORK IN BASEMENT MEMBRANES IS A CRITICAL EVENT IN MANY NORMAL AND PATHOLOGICAL CONDITIONS INCLUDING TISSUE REMODELLING, WOUND HEALING, TUMOR CELL METASTASIS, AND ANGIOGENESIS. THE 72 KD TYPE IV COLLAGENASE IS A NEUTRAL METALLOPROTEASE CAPABLE OF DEGRADING… more
Company: Multichannel Concepts Inc Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: WITH THE INCREASING AVAILABILITY OF MULTICHANNEL EXTRACELLULAR MICROELECTRODE ARRAYS AND THE POTENTIALLY LARGE NUMBER OF SIMULTANEOUS RECORDINGS IN NEURAL SYSTEM STUDIES, DATA PROCESSING CAPABILITY AND CAPACITY ARE VERY IMPORTANT. AN AUTOMATED ON-LINE NEURAL SPIKE SEPARATION, SORTED DATA COLLECTION… more
Company: MULTISPECTRAL SOLUTIONS, INC. Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: ECM systems incorporating repeater, transponder and noise jamming techniques can produce a plethora of extraneous false targets which then give rise to bogus target track files. False target detections and subsequent false tracks can so overload a radar's processing hardware/software that the normal… more
Company: Neocera , LLC Agency/Program/Year/Phase: NASA / SBIR / 1991 / 2
Abstract: AMONG THE POTENTIAL APPLICAITONS OF THE NEW HIGH-TEMPERATURECERAMIC SUPERCONDUCTORS ARE MICROWAVE DEVICES FOR COMMUNICATIONS APPLICATIONS. FABRICATION OF SUCH DEVICES WILL REQUIRE WILL-CONTROLLED TECHNIQUES FOR PREPARING THIN FILMS OF THE MATERIALS ON SUBSTRATES HAVING LOW MICROWAVE LOSSES SUCH AS… more
Company: Neocera , LLC Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: N/A
Company: New Horizons Diagnostics Agency/Program/Year/Phase: NASA / SBIR / 1991 / 2
Abstract: A PATENTED SELF-CONTAINED SOLID PHASE COLORIMETRIC IMMUNOASSAY FOR THE RAPID IDENTIFICATION OF BIOLOGICAL ANALYTES IS PROPOSED FOR USE IN MICROGRAVITY ENVIRONMENT. THIS SIMPLE TO USE NONINSTRUMENTED DEVICE CAN DETECT AS FEW AS 2 X 10(3) GROUP A STREPTOCOCCI IN LESS THAN 5 MINUTES. THE TEST DEVICE IS… more
Company: Nichols Technologies Inc. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: THE LONG-TERM OBJECTIVE OF THIS RESEARCH IS TO PROVIDE A COMMERCIAL FACILITY AND REACTORS FOR THE PRODUCTION OF THIN POLYMER HERMETIC INSULATING MATERIALS SPECIFICALLY DEVELOPED FOR THE PHYSIOLOGICAL ENVIRONMENT AND FOR THE PREVENTION OF ELECTROLYTIC CORROSION OF INTEGRATED CIRCUIT METALLIZATIONS… more
Displaying 6651 – 6675 of 7760 Awards
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