Abstract:DESCRIPTION (provided by applicant): Though the USPSTF recommends all clinicians intervene with obese adults (AHRQ, 2003), less than half of patients are assessed, counseled, or otherwise treated for obesity. This project will create an innovative web-based continuing professional development… more
Abstract:DESCRIPTION (provided by applicant): In the SBIR Fast-track application, we propose to create and evaluate an online skills training experience for medical students to properly assess patients in pain, minimize potential opioid misuse, and maximize pain treatment. Our curriculum will provide an… more
Abstract:DESCRIPTION (provided by applicant): Multiple sclerosis (MS) is an inflammatory autoimmune disease in young adults, affecting more than 530,000 people in the United States and approximately 2 million worldwide. MS is characterized pathologically by inflammation, demyelination and axonal damage in… more
Abstract:The Missile Defense Agency (MDA) has become more reliant on First Principles Model and Simulation to assess the effectiveness of the Ballistic Missile Defense System (BMDS). This is due in part to the continued growth in cost and schedule for ground based testing program that have traditionally… more
Abstract:Weldments that join plates of aluminum or steel combat vehicle hulls can be the lowest strength area of the structure and thus provide a decreased level of ballistic protection. To avoid welds, seamless hulls could be formed from thick plate if a suitable manufacturing process is developed. Corvid… more
Abstract:ABSTRACT: The potential of scramjet engines for use by the U.S. military would revolutionize countermeasures enabling rapid responses to global hot spots. The scramjet traveling at hypersonic speed cannot use rotary power typically employed at sub-Mach velocities, while auxiliary power units and… more
Abstract:DESCRIPTION (provided by applicant): PERMANENT 100% ANTIMICROBIAL MEDICAL PLASTIC Combating infections is one of the major goals of the entire medical community due to the exponential cost associated with care of an infected patient. Technology innovationsto reduce infection brought about by… more
Abstract:The overall objective of this proposal is to develop a novel, simple, low-cost, on-site DOA test device and kit for measuring drugs of abuse for multiplex analysis capabilities based on the Contractor's patented ultra-sensitive Time-Resolved Luminescent Lateral Flow Assay Technology with… more
Abstract:DESCRIPTION (provided by applicant): Nearly two-thirds of all medical imaging procedures in the United States are performed in physician offices, yet few of these small healthcare providers can afford picture archiving and communication systems (PACS) needed to exchange these images with large… more
Abstract:MDA seeks to maximize the utility of collected sensor data through a fusion architecture that provides an integrated view of the battlespace. IAVO proposes research and development of a fusion architecture, which employs novel algorithmic techniques using a foundation of sound stochastic theory,… more
Abstract:The US Navy seeks innovative technologies to fuse dynamic imagery and static models into a single synthesized multi-sensor scene. This data fusion will allow targeting and mission planning in a volumetric 3D space, a feat which has never before been available. To readily move to the next frontier in… more
Abstract:Motivated by the uncertainty in rising fuel expense and fleet total ownership costs, the US Navy is currently addressing power and energy management as a prime research focus area with the goal of strategically allocating energy resources to increase efficiency. In support of these goals, they have… more
Abstract:DESCRIPTION (provided by applicant): The purpose of this project is to develop, produce, and evaluate a competency-based multimedia, eLearning course for human service professionals. The overall program will be used to deliver a 21/2 -hour, six-module, eLearning course on the web, providing users… more
Abstract:DESCRIPTION (provided by applicant): The purpose of the proposed project is to develop, implement, and evaluate the use of an Internet-based eLearning multimedia program that will allow foster care social workers, educators, and other youth workers to planone-day real world simulations that would… more
Abstract:DESCRIPTION (provided by applicant): Syndrome (ARS), including a lethal myelosuppression due to the sensitivity of proliferating hematopoietic stem/progenitor cells (HSPCs) to ionizing radiation (IR). No effective therapy exists to mitigate the hematologictoxicities of TBI. Herein G-Zero… more
Abstract:DESCRIPTION (provided by applicant): The objective of this proposal is the development, evaluation and validation of an accurate, low cost diagnostic test that can discriminate prostate cancer from benign prostatic hyperplasia to a Specificity of 85% at aSensitivity of 85%. Prostate cancer is the… more
Abstract:DESCRIPTION (provided by applicant): Project Summary/Abstract The Specific Aim of this proposal is to test the efficacy of Light-Activated Anti-Microbial fabrics to biologically inactivate three model pathogens, influenza H1N1 swine, respiratory syncytial virus (RSV) and cowpox virus (as a… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project describes a new approach for reducing infections associated with indwelling medical devices. Bacteria on medical devices are particularly challenging to treat because they form a protective matrix called a biofilm on the surface of the… more
Abstract:DESCRIPTION (provided by applicant): Bacterial infections are responsible for an estimated 100,000 deaths in the United States each year, and despite the dire unmet medical need, few new treatment options are being developed. One of the most significant hurdles in effectively treating bacterial… more
Abstract:DESCRIPTION (provided by applicant): Chronic wounds that fail to respond to traditional therapeutic interventions afflict millions of people each year, and direct costs associated with treating these wounds are estimated at 5 to 10 billion annually. Eradication of pathogenic… more
Abstract:DESCRIPTION (provided by applicant): Cystic fibrosis (CF) is the most common life shortening inherited disorder amongst Caucasians, and Pseudomonas aeruginosa pulmonary infections are the leading cause of mortality in CF patients. Treatment of patients infected with P. aeruginosa is complicated by… more
Abstract:Bennett Aerospace of the Research Triangle, North Carolina, and Team Members Virtual Heroes, and Duke University Medical Center and Health System, propose to develop a web-based, multiplayer, 3D serious medical game as a cognitive trainer, called HumanSim
Abstract:ABSTRACT: Bennett Aerospace proposes to develop a curved, transparent, binocular, full-color holographic optical waveguide display for head-mounted displays, helmet-mounted displays (HMDs), and other transparent application areas such as visors and windshields where curved displays are desired for… more
Abstract:Bennett Aerospace of the Research Triangle Park area of North Carolina, and Team partners propose to develop an HF RF distribution system that will consolidate the signals from multiple transmitters onto two antennas with much less transmitter output power. This system has the potential to negate… more
Abstract:Bennett Aerospace of the Research Triangle Park area of North Carolina, and Team Members propose to develop an E-beam thermal modeling methodology and assessment tool that can be used to simulate the various machine parameters in an E-beam metal additive manufacturing process through a multi-physics… more
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