Abstract:DESCRIPTION (provided by applicant): Back pain is one of the leading reasons for physician visits in the United States and in many cases requires surgical intervention. In the United States, there are over 500,000 spinal fusion surgeries every year, and the frequency of these surgeries is projected… more
Abstract:DESCRIPTION (provided by applicant): Over 700,000 surgical hernia repairs are performed each year in the United States and despite recent advances, a significant rate of recurrence persists. Of these surgeries, 100,000 are for incisional or visceral herniarepairs, which cost 1.7B annually and have a… more
Abstract:DESCRIPTION (provided by applicant): Calvarial reconstruction continues to present challenges for surgeons. Although the gold standard for restoration of the skull is autologous bone, particularly from the removed flap, substitutes are often necessary dueto the flap becoming infected or infiltrated… more
Abstract:DESCRIPTION (provided by applicant): Burn injuries and chronic wounds present a significant burden to patients and the US healthcare system. Each year in the US, there are 450,000 burns that require medical treatment and 45,000 burns that require hospitalization. One of the most common causes of… more
Abstract:ABSTRACT: A micro-camera composite focal plane array (CFPA) comprised of a primary optic and an array of camera//lens modules with high sensitivity, low noise CMOS image sensors provides a low cost, compact solid-state imaging system for wide area persistent surveillance across a range of lighting… more
Abstract:The modernization of the US swine industry has been critical to the sustainability and global competitiveness of US swine production. At the same time, modernization has also required dramatic changes in animal management. By housing pigs indoors, producers have caused the unintended problem of iron… more
Abstract:DESCRIPTION (provided by applicant): Patients with chronic anemia (i.e., anemia of inflammation) frequently find that iron repletion cannot be achieved with oral iron fortificants. The current standard of care for these patients is infusion of intravenous(IV) iron-carbohydrate complexes. These… more
Abstract:DESCRIPTION (provided by applicant): Dry Eye disease is an affliction that impacts as many much as 20% of the U.S. population over age 50, and is even more prevalent in the Asia Pacific. Dry eye therapies are currently a 1.7B market, growing at 10% annually. Treatment is primary palliative,… more
Abstract:DESCRIPTION (provided by applicant): The dire implications of the adult obesity epidemic grow worse over time. Despite front page coverage and universal agreement that the epidemic in weight gain and secondary disease establishment must be addressed, the problem continues. Intended Impact: We… more
Abstract:DESCRIPTION (provided by applicant): Step2 CS Training in Alcohol Addiction and the Medical Consequences of Alcohol This project will create a website, WebOSCE.com, to provide a unique training opportunity for medical students to: 1) prepare for the USMLE(R) Step 2 CS (Clinical Skills) examination,… more
Abstract:DESCRIPTION (provided by applicant): An estimated 116 million US adults suffer from chronic pain at an estimated cost of 635 billion and, unfortunately, existing pain management training is not adequately preparing health professionals to address this area . Opioid prescription drugs, obtained… more
Abstract:DESCRIPTION (provided by applicant): An estimated 116 million US adults suffer from chronic pain at an estimated cost of 635 billion and, unfortunately, existing pain management training is not adequately preparing health professionals to address this area . To address this gap we propose to… more
Abstract:Project Goal/Intended Impact: To improve outcomes of in-treatment addicted patients by providing a virtual reality game as part of a regular health care visit with a health care provider. The game can be played with an off-the-shelf commercially available gaming system (Microsoft Xbox Kinect)… more
Abstract:DESCRIPTION (provided by applicant): Our overall goal is to market a COG compound (aka. apoE-mimetic peptides) for the treatment of patients with asthma. Cognosci has discovered, patented and published a novel series of COG compounds which are functionalmimetics of apolipoprotein-E. These COG… more
Abstract:ABSTRACT: The US Air Force (AF) is increasingly being required to conduct operations in complex environments with friendly forces or noncombatants in relatively close proximity to targets. Currently there is no single weapon which can offer a satisfactory range of lethal effects on the variety of… more
Abstract:Corvid Technologies is pleased to offer a solution for remotely delivering explosive detection materials. The objective is to deliver a liquid explosive detection agent with a 40mm projectile using existing launch systems. Innovative materials and design techniques will be used to ensure accurate… more
Abstract:Corvid Technologies is excited to offer a unique solution for protecting tactical vehicles during high-speed external transport. The innovative design employs a fabric net structure rigged to the vehicle which significantly reduces the impeding air velocity on critical components. This approach… more
Abstract:The primary objective of this effort is to further develop and validate a computational capability which can be used to assess propulsion systems for compliance with insensitive munitions (IM) requirements. Comprehensive testing to ascertain IM compliance for such systems is time consuming and… more
Abstract:Corvid Technologies is pleased to offer this SBIR Phase II proposal. In the proposed effort, we will extend the high-fidelity analysis processes demonstrated during Phase I to generate large-scale, production-quality databases for intercept debris fragments. Our approach utilizes an innovative… more
Abstract:DESCRIPTION (provided by applicant): The treatment of injuries or diseases affecting articular or elastic cartilage poses important unmet challenges to the medical community. The goal of this Phase I SBIR is to further the development of a method for themanufacture of a biologically-derived… more
Abstract:DESCRIPTION (provided by applicant): Angiogenesis and hypoxia can significantly influence the efficacy of therapy and the behavior of surviving tumor cells. This important fact is supported by a vast amount of literature on pre-clinical models and clinical studies. There is growing demand for… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will address new regulations being enacted in the shipping industry requiring Sulfur Oxides (SOx) reduction from engine emissions. Many commercial scrubber systems effectively remove SOx from engine emissions, yet none are designed to… more
Abstract:DESCRIPTION (provided by applicant): It is currently estimated that 15% of the world's population is undernourished and 5 million childhood deaths a year are attributable to malnutrition. The ability to feed the world in the future will be even more difficult due to population growth, climate… more
Abstract:DESCRIPTION (provided by applicant): Liver toxicity is a major barrier to the FDA approval of many new drugs. Moreover, since the liver is the major site of metabolism of most xenobiotics it is essential to know how the liver metabolizes new drug. Becauseof the many species differences between… more
Abstract:DESCRIPTION (provided by applicant): We propose to develop an operating-room-ready system for needle guidance in soft tissue, which fuses intra- operative ultrasound and pre-operative X-ray computed tomography (CT) data by combining two novel technologies:1) a radically different way of visualizing… more
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