Abstract:Boron Neutron Capture Therapy (BNCT) has a clear theoretical advantage over other techniquesas a method of delivering cell-killing radiation to tumors. The inability of leukemia cells to synthesizeasparagine and the requirement of exogeneous asparagine by tumor cells provide an excellentopportunity… more
Abstract:Boron analogs of biomolecules exhibit considerable therapeutic potential in the areas of cancertreatment, bone disorder (such as osteoporosis), hyperlipidemia and inflammation. Considerable activityhas been demonstrated in cell cultures and rodent models. Most of the agents tested for acute… more
Abstract:The proposed investigation will characterize the physical properties of Chemically Bonded Ceramic (CBC) tooling currently being evaluated as production tooling by the automotive and furniture industries for fabricating plastics and molded organic foams. This information will be used to modify the… more
Abstract:THE RAPID DEVELOPMENT OF THE TECHNOLOGY FOR PRODUCING HIGH QUALITY SINGLE CRYSTAL SiC WAFERS AND THIN FILMS PRESENTS THE OPPORTUNITY TO FABRICATE SOLID-STATE DEVICES WITH POWER-TEMPERATURE CAPABILITY FAR GREATER THAN DEVICES CURRENTLY AVAILABLE. THIS CAPABILITY IS IDEALLY SUITED TO THE APPLICATION… more
Abstract:The military has a need for high power/high frequency electronics which can operate at high temperatures for applications such as radar and electronic warfare systems. While Si and GaAs are already being used near their limits of output power and operating temperature, the potential of SiC is just… more
Abstract:Silicon carbide (SiC) is the ideal semiconductor for fabrication of solid state devices for power conditioning for the all-electric airplane, turbine engine actuators, and space-based power systems. These applications require switches and amplifiers capable of large currents with relatively low… more
Abstract:AN OPTICAL RELAY USED TO IMAGE TEXT, GRAPHICS, AND VIDEO IN A HEAD MOUNTED DISPLAY (HMD) SYSTEM IS PROPOSED. COMPUTER GENERATED HOLOGRAMS WILL BE EMPLOYED IN CONJUNCTION WITH CONVENTIONAL-REFRACTIVE OPTICS IN ORDER TO REDUCE THE WEIGHT AND SIZE OF THE SYSTEM WHILE ENHANCING ITS PERFORMANCE. BOTH… more
Abstract:ELDERSOURCE IS A COMPANY WITH THE MISSION OF PROVIDING OLDER PROPLE WITH PRODUCTS AND SERVICES THAT WILL FACILITATE THEIR EFFORTS TO REMAIN HEALTHY, ACTIVE AND INDEPENDENT. THE OBJECTIVE OFTHIS RESEARCH WAS TO DEVELOP A PRODUCT REQUIREMENTS AND STANDARDS EVALUATION TOOL (PRODUCT EVALUATION… more
Abstract:This project will develop cancer education pamphlets targeted toward low literate femalepopulations. An effective way to reduce the incidence and mortality from breast cancer is to focusprevention and early detection efforts toward low literate female populations, a subgroup at high riskfor late… more
Abstract:GENE TEC HAS A PROPRIETARY CARRIER DEVICE FOR PROCESSING SPECIMENS TO DETECT DNA OR ANTIGENS. THE CARRIER FORMAT WAS DESIGNED TO INTEGRATE SPECIMEN COLLECTION, TRANSPORT AND SAMPLE PROCESSING WITHIN THE SAME DEVICE. THE FIRST CARRIERS ARE DISPOSABLE DEVICES WHICH ARE DESIGNED TO ACCEPT STANDARD… more
Abstract:The compound 2,3,7,8-tetrachlorodibenzodioxin (2,3,7,8-TCDD) has been called the most toxic compound known to man. 2,3,7,8-TCDD is globally distributed but is found in high concentration at many hazardous waste sites associated with the production and use of chlorinated pesticides/herbicides.… more
Abstract:Proposal To Assess State-of-the-art Dc Switoh System For Isolating Battery Voltage In Emergenoy Oonditions Provides A Conoeptual Design Interfaoe With Ship's Battery And Phase II Development Sohedule And cost Estimate.
Abstract:Proposal to assess state-of-the-art high current, low voltage (less than 1000 volts) switch and conductor system that minimizes stray magnetic fields. Provides a conceptual design of a switch, bus and flexible joint devices; and Phase II development schedule and cost estimate.
Abstract:FOR THE BIOMONITORING OF DNA DAMAGE IN HUMANS POTENTIALLY EXPOSED TO GENOTOXIC AGENTS, AN OPTIMAL METHOD SHOULD BE CAPABLE OF DETECTING MANY CLASSES OF DNA DAMAGE IN A VARIETY OF CELL TYPES, SHOULD PROVIDE DATA AT THE LEVEL OF THE INDIVIDUAL CELL, AND SHOULD BE SENSITIVE, RAPID AND COST EFFECTIVE.… more
Abstract:The introduction and increasing use of several man-made and synthetic fibers have raisedconcern over their possible health effects in view of their similarity to asbestos, a known carcinogen.Animal studies have clearly indicated the carcinogenic effects of asbestos fibers, Furthermore, theeffects of… more
Abstract:We propose determining the feasibility of employing distributed artificial intelligence algorithms and the Joint Tactical Information Distribution System (JTIDS) to (1) integrate heterogeneous, geographicaly dispersed information and knowledge sources (for improved siti\uation awareness) (2)… more
Abstract:A group of chemotactic cytokines belonging to the "chemokine" family have recently beenidentified and molecularly cloned. These include the archetypal alpha and beta subfamily membersinterleukin-8, a neutrophil selective chemoattractant and the monocyte chemoattractant protein-1(MCP-1). Chemotactic… more
Abstract:This proposed effort utilizes an existing DoD technology, known as a traveling wave tube (TWT), as a broadband, high-power plasma source. The TWT will permit optimization of processing parameters over a frequency range larger and wider than has previously been examined and will allow optimum,… more
Abstract:The proposed project is to develop a microwave processing system for variable frequency processing of thermosetting polymer matrix composites (PMCs). Combining an existing production technology with an innovative application of DoD Traveling Wave Tube (TWT) technology will enable an increase in the… more
Abstract:Our company will develop a method of automatically programming neural-networks to extractneeded information from databases of biological and chemical information. We will pursue the creationof a framework for training a neural network to predict the toxic and carcinogenic properties ofchemicals… more
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