Abstract:AS PROSTATE CANCER HAS RECENTLY BECOME THE MOST WIDELY DIAGNOSED FORM OF CANCER IN UNITED STATES' MALES, CLINICIANS ARE EXPECTED TO SEEK MORE EFFECTIVE TREATMENT MODALITIES. ONE OF THESE MAY BE HYPERTHERMIA AS AN ADJUNCT TO RADIATION AND CHEMOTHERAPY. THE MAIN LIMITATION TO THIS MODE OF THERAPY HAS… more
Abstract:We will develop a computer program which will be used as an integral part of intravascular ultrasonic units for assessing the severity of arterial lesions. The software will use the digitized vessel geometry data directly from the units to produce a quantitative assessment of stenosis severity using… more
Abstract:MANY OF THE DEFECTS THAT APPEAR IN WOOD DURING DRYING OR DURING MATCHINING ORIGINATE FROM SHRINKAGE DURING DRYING AND FROM ITS ASSOCIATED STRESSES. THE ABILITY TO SENSE SHRINKAGE AND STRESSES MAY ALLOW SUCH DEFECTS TO BE AVOIDED NY CAREFUL CONTROL OF TEMPERATURE, HUMIDITY, AND AIRFLOW CONDITIONS… more
Abstract:Deep vein thrombosis (DVT) and resultant pulmonary emboli (PE) represent significant morbidity and mortality in the U. S. A. Existing detection modalities such as contrast venography, ultrasound, and non-specific radiopharmaceuticals do not exhibit the sensitivity or specificity in all areas of… more
Abstract:Interleukin-8 (IL-8), a newly characterized proinflammatory cytokine, is chemotactic for polymorphoneutrophils (PMNs). It produces several other agonist effects, including granule release of degradatproduction of oxygen-derived free radicals. These effects are mediated by specific high affinity… more
Abstract:The objective of the proposed work is to develop a unified and optimum numerical method for solving fluid-structure interaction problems. We propose to use an unstructured solution-adaptive topology for both fluid and structure, and to discretize the governing equations for both using a common… more
Abstract:Lipoprotein(a) [Lp(a)] is a cholesterol-rich particle that contributes to the total risk of coronary heart disease (CHD) when plasma levels are elevated. Elevated Lp(a) levels can be treated with niacin. Lp(a) differs from other lipoproteins by the presence of a glycoprotein, called… more
Abstract:Vertical Line Arrays (VLAs) have the potential of significantly improving the performance of underwater acoustic systems in shallow water scenarios. Realizing this improved performance in a low storage volume, cost effective system is dependent on an Integrated Hydrodynamic Deployment System which… more
Abstract:Aircraft which travel at high Mach numbers require a very large internal heat sink to protect the engine and airframe from high heat loads. Endothermic fuels are attractive for hypersonic propulsion systems because they increase the fuel heat sink capacity. We propose to develop a compact and… more
Abstract:We propose development of an innovative system for converting the energy content of refuse to electricity. The key element of the system is a supplementary-fired exhaust-heated gas turbine that has a thermal efficiency of 50%. The engine has two combustors: (1) an exhaust-heating combustor that is… more
Abstract:This project will develop a long duration, open circuit respirator with several key advantages over existing technology: it provides cool, fresh breathing air for long periods (potential up to 2 hours) with an open circuit system, it assures positive faceplate pressure, and it is very lightweight.… more
Abstract:Decompression sickness (DCS) presents a risk of serious injury or death and affects the operational readiness and capabilities of NASA military and civilian astronauts, aviators and divers and other individuals who are exposed to moderate environmental pressure transients. During this project,… more
Abstract:Future spacecraft will require reliable, passive thermal control systems. Capillary pumped loops (CPLs) are currently limited by the performance of conventional capillary evaporators because their heat transport capacity and their heat flux capability are low. We propose to develop a reliable CPL… more
Abstract:This proposal addresses the development of a novel permanent magnet motor for a miniature centrifugal compressor. The compressor is a critical component in a low capacity, vibration free, long life cryocooler. Key features of the development include the incorporation of a permanent magnet in a… more
Abstract:Recent developments in orifice pulse tube refrigerator (OPTR) technology have made these devices competitive with Stirling cycle cryocoolers for long-life spacecraft service, but further improvements in efficiency, capacity, miniaturization, and reliability are required. We propose an innovative and… more
Abstract:Current fabrication techniques for millimeter wave (MMW) waveguide assemblies are inherently costly and poorly suited to realizing economies of scale. Improved processes for manufacturing these components at reasonable costs are required to exploit recent advances in MMW technology. In this project… more
Abstract:The use of robot technology in many military and private sector applications has been limited due to the application-specific nature of available robot hardware and control software. the use of robots with multiple sensors, kinematic redundancy, and mobile bases has been restricted because of the… more
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