Abstract:Recent research has shown that Superconducting Quantum Interference Devices (SQUIDs) may be used to measure the very weak magnetic signals in Magnetic Resonance Imaging (MRI) at ultra-low magnetic fields in the milli-tesla range or below. However, the signal-to-noise ratio (SNR) is quite low,… more
Abstract:Detectors utilized in high energy and nuclear physics research have, historically, been instrumented with FET amplifiers operated in the cryogenic environment. These amplifiers require heated operation, suffer from large 1/f noise, are very sensitive to microphonic pickup, and dissipate high power.… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project aims to develop a topical formulation incorporating a polymeric platform that releases therapeutic levels of nitric oxide gas, and assess its efficacy in dispersing wound-relevant bacterial biofilms. The intellectual merit of the… more
Abstract:In this program nBn Technologies proposes to developed new nBn FPAs for long wave IR. This is based on III-V material systems grown in MBE. We will concentrate on material systems that will fit the nBn concept, especially holes transport and passivation free (the barrier used as passivation).The… more
Abstract:DESCRIPTION (provided by applicant): Scleroderma is an autoimmune, connective tissue disorder which causes fibrosis of the skin and internal organs. In the skin, there is overproduction of extracellular matrix, and type 1 and 3 collagen. The disease involves vascular breakdown where the blood… more
Abstract:The technical approach to this project is to design and develop an improved, three-phase grid connect unit (GCU) capable of switching loads up to 100 kW. The GCUs would be used in a system architecture where they allow for groups of loads to be"gathered"under a single generator. When the… more
Abstract:ABSTRACT: This SBIR Phase I proposal proposes to develop a High Speed SWIR Scene Projector that can operate at 800 Hz with growth potential to 2 kHz, and a 1024x1024 spatial format scalable to 2kx2k in the future fabrication. The threshold operational region could exceed the specified 1200 to… more
Abstract:ABSTRACT: In order to minimize the cost and complexity of Missile Defense Agency (MDA) Infrared (IR) guided interceptor systems, and Air Force Theater Defense, MDA/Air Force established the Kinetic-kill-vehicle Hardware-in-the-Loop (KHILS) Simulation Facility for the purpose of performance testing… more
Abstract:In 2011, the US electricity generation was 4344 billion kWh gross with 821 TWh (19%) from nuclear power reactors. The US has 104 nuclear power reactors, 69 pressurized water reactors and 35 boiling water reactors, in 31 states, operated by 30 different power companies. Almost all of the US nuclear… more
Abstract:The goal of this project is to implement a Universal Exchange Language suitable for nationwide adoption across healthcare providers, and accessible to patients and medical researchers under appropriate protections for security and privacy, as envisioned in the 2010 PCAST report on Health Information… more
Abstract:The manufacturing and engineering industry needs more cost effective and easy-to-use high- performance computing (HPC) modeling and simulation tools to design, test, and analyze innovative components and products. For 92% of the small- to medium-sized manufacturers with less than 100… more
Abstract:Numerical simulations play a crucial role in the DOE High Energy Physics (HEP) Cosmic Frontier program. They provide a theoretical framework with which to compare observational data from surveys. Through such comparisons, significant breakthroughs are made. These breakthroughs can guide scientists… more
Abstract:ABSTRACT: Studying the effects of electromagnetic energies on human anatomy requires the consideration how the effects change for different anatomical poses and body types, e.g., for different body-mass indexes. Acquiring such a wide range of data, however, can be problematic given medical scanner… more
Abstract:ABSTRACT: Kitware proposes MAP-Tk, the open-source Motion imagery Aerial Photogrammetry Toolkit, designed for optimized sparse bundle adjustment (SBA) of FMV and WAMI. Our proposed toolkit has a highly configurable and modular design supporting interchange of existing solutions for feature… more
Abstract:DESCRIPTION (provided by applicant): Image-based evaluation of pathologies over time is complicated by variability in image acquisition and patient positioning, deformations due to respiratory and cardiac motion, and the clinical standard in radiology of comparing unaligned images. This application… more
Abstract:DESCRIPTION (provided by applicant): Nearly 1.7 million Americans suffer traumatic brain injury (TBI) annually, which constitutes an important and significant US medical health concern. Although neuroimaging plays an important role in pathology localization and surgical planning, TBI clinical care… more
Abstract:DESCRIPTION (provided by applicant): The Focused Assessment with Sonography for Trauma (FAST) procedure is an ultrasound examination performed to identify intra-peritoneal hemorrhage or pericardial tamponade. FAST involves the detection of free fluid in ultrasound images from four specific abdominal… more
Abstract:DESCRIPTION (provided by applicant): This application addresses Innovations in Biomedical Computational Science and Technology Initiative PAR-09-220. Healthcare is moving towards fully digitized patient records. Surgical pathology represents a challenge inthat high resolution imaging of tissue… more
Abstract:DESCRIPTION (provided by applicant): Approach-specific, Multi-GPU, Multi-tool, High-realism Neurosurgery Simulation Surgical treatment of neurological diseases is complicated and requires advanced training. However, compressed internship schedules in hospitals creates a challenge to young surgeons… more
Abstract:This Phase II project will work toward increasing the math and science problem solving capacities of high need rural students and their teachers. Math and science and the ability to solve problems in these disciplines lie at the heart of technical innovation and economic security in today &… more
Abstract:LightSpin Technologies, Inc. proposes to develop radiation-hard GaInP Photomultiplier Chips. GaInP is extraordinarily radiation hard, capable of withstanding at least 100,000-fold higher radiation flux than silicon. LightSpins GaInP Photomultiplier Chip technology enables the production of GaInP… more
Abstract:For a wide range of remote sensing applications, there is a critical need to develop imaging arrays that simultaneously achieve high spatial resolution, high sensitivity, and sub-nanosecond timing resolution. Many of these remote sensing applications furthermore are satellite and space based, where… more
Abstract:DESCRIPTION (provided by applicant): LightSpin Technologies, Inc., proposes a Phase II SBIR to develop a new photodetector component (the GaAs Photomultiplier Chip ) for ultrafast TOF-PET applications. The goal is to build a solid-state photodetector witha single photon timing resolution of 50 ps… more
Abstract:The Phase I project will develop a suite of diagnostic sensors using Direct Write technology to measure temperature, surface recession depth, and heat flux of an ablative thermal protection system (TPS) in real time, which can be integrated to support TPS evaluation and in-situ diagnostics during… more
Abstract:The overall objective of the Phase I and Phase II proposed effort is to design and demonstrate the ability to develop a high-speed shock tolerant composite flywheel energy storage system (FESS) using a low cost manufacturing process. The Phase I tradeoff design studies will assess the FESS size,… more
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