Abstract:Zeigler Bros., Inc. (ZBI) has teamed with Harrisvaccines, Inc. (HV) to develop a new aquafeed manufacturing platform for the practical application of underutilized feed additives. These include enzymes, immune-stimulating compounds and biologics that require specialized protection to ensure they… more
Abstract:In this proposal Zeomedix proposes to develop a dressing for infected trauma wounds based on its zeolite encapsulating nitric oxide (NO) technology. Nitric oxide has been shown to enhance the wound healing process as well as act as a powerful antibacterial agent. However, delivery of nitric oxide… more
Abstract:DESCRIPTION (provided by applicant): In the US, about 36,000 deaths occur each year due to influenza and its associated diseases, and 85% of these deaths are in the elderly population. Immunization with flu vaccine is considered the best way to prevent seasonal epidemics and pandemics of influenza.… more
Abstract:The Urban Forestry Modeling and Prioritization Tools project addresses the research and tasks necessary for creating cost effective, web-based software that assists urban foresters with strategically selecting planting locations in order to maximize impact on both the environment and local… more
Abstract:Phishing fools end-users into disclosing sensitive information or downloading malware. Commercially available solutions have shown limited success in stopping these attacks. We aim to refine and commercialize novel anti-phishing email and web filtering techniques that overcome these limitations.… more
Abstract:NASA Glenn is examining small fission reactors for future space transportation and surface power applications. The reactors would have an 8 to 15 year design life that could be available for a 2020 launch to support future NASA science missions. Both 1 kWe thermoelectric and 3 kWe Stirling systems… more
Abstract:This project aims to increase the reliability of radio frequency (RF) devices used in accelerator facilities by reducing/eliminating corrosion and erosion produced from the high purity de-ionized water cooling systems. Although metal interconnects are required for electrical and thermal … more
Abstract:This Small Business Innovation Research project proposes to develop a first-of-its-kind hybrid solar-coal gasification technology. The current direct heating gasification technology has two shortcomings: (1) greenhouse gases, resulted from the coal combustion, diluting the syngas product, and… more
Abstract:Silicon carbide (SiC) based devices are currently under investigation for their improved efficiency and high thermal stability. Compared to silicon, SiC has an exceptionally high thermal conductivity and also exhibits better mechanical properties. However, limited research has been performed on SiC… more
Abstract:The proposed SBIR Phase I program will develop an innovative fuel flexible reformer for a portable Solid Oxide Fuel Cell (SOFC) power generation system used in the battlefields. The fuel reformer is non-catalytic and can operate with different fuels including methanol, propane, and JP fuels,… more
Abstract:ABSTRACT: Next-generation aircraft are experiencing increasing thermal challenges due to heat generation from avionics, as well as requirements to lift this heat to temperatures high enough for rejection from the platform. Efforts have demonstrated vapor compression systems (VCS) offer a… more
Abstract:This Small Business Innovation Research Phase I project will develop an advanced thermoelectric generator (TEG) that will improve the overall efficiency of 100-kW class generator sets (gensets). Advanced Cooling Technologies, Inc. (ACT) proposes a novel thermoelectric generation system to convert… more
Abstract:DESCRIPTION (provided by applicant): The goal of this SBIR research program is to develop a novel small molecule inhibitor of latent Epstein-Barr Virus (EBV) infection. EBV is a ubiquitous gamma- herpesvirus that has been classified by the World Health Organization as a human carcinogen. Vironika,… more
Abstract:DESCRIPTION (provided by applicant): The goal of this program is to develop novel inhibitors of human neutral ceramidase (ASAH2) that are effective as therapeutic agents for Inflammatory Bowel Diseases (IBDs). Sphingolipids are being increasingly recognized as key mediators of inflammation, and are… more
Abstract:DESCRIPTION (provided by applicant): There is a hidden epidemic of urinary incontinence (UI) in the United States. Thirteen to twenty million Americans suffer from UI, including 10% to 30% of women and 1.5% to 5% of men. Ten percent of women have symptomsso severe that they undergo surgery for UI or… more
Abstract:DESCRIPTION (provided by applicant): This STTR Phase II application is to finalize the one-of-its-kind Assessment of Liability and Exposure to Substance use and antisocial behavior(c) (ALEXSA(c)) for educator, pediatric, prevention and epidemiology uses. The ALEXSA system, first funded by a NIDA… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project proposes to develop a noninvasive intracranial pressure (ICP) monitor based on a pilot clinical study correlating ocular blood pressure and blood flow parameters to ICP. The proposed novel device will combine several standard medical… more
Abstract:Develop a low-cost high cycle fatigue experimental and analytical capability to evaluate complex gas turbine engine rotor and airfoil systems for the purpose of component and design tool validation.
Abstract:This Small Business Technology Transfer (STTR) Phase I project will model, design, simulate, develop and transition to industrial partners the key elements of Frequency Agile Reconfigurable Radios that incorporate both medium-data-rate wireless wide area network (WWAN) radios and… more
Abstract:Our objective is to provide a semi-automated system to generate and verify scalable, high fidelity, multi-dimensional, social networks with realistic distributional, temporal and spatial characteristics as networks and as event sequences. This enables the user to generate networks varying in size,… more
Abstract:Our objective is to enable military analysts to rapidly produce intelligence results related to human social contexts, and to improve the quality of the underlying analyses based on dynamic meta-network data. We focus on the visual analytics and decision aids needed to support target identification,… more
Abstract:Our objective is to enable military analysts to rapidly produce intelligence results regarding adversarial groups and so diverse types of covert networks, and to improve the quality of the underlying analyses. We focus, on the data entry and cleaning problems. We propose a mixed-initiative… more
Abstract:Myocardial infarction (MI) afflicts more than one million persons per year in the United States alone. MI results in permanent left ventricle (LV) scarring that causes diminished pump efficiency and, commonly, heart failure. Towards reduction or elimination of scarring, there is increasing interest… more
Abstract:This work proposes to address the capability gap for low frequency, low power transducers in a small form factor. We propose to use newly evaluated resonance modes of single crystal piezoelectrics that provide savings of over 75% in transducer volume. The program will evaluate the shear mode… more
Abstract:TRS proposes to develop a simple-to-use, launch capable, ultrasound transducer that is capable of producing the necessary bandwidth to accurately determine in vivo bone characteristics that correlate to loss of strength in astronauts in long-duration space flights (microgravity). The transducer… more
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