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Displaying 926 – 950 of 5210 Awards
Company: POLARIS HEALTH DIRECTIONS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 2
Abstract: DESCRIPTION (provided by applicant): The prevalence and severity of mental health and chemical dependency disorders on college campuses have reached crisis levels. A national survey of 29,230 college students in 2002 found that, at some point during the pr evious year, 45 percent had felt so… more
Company: POLARIS HEALTH DIRECTIONS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 2
Abstract: Evaluate the impact of STaRS upon increasing the number of referrals provided for substance abuse treatment and HIV screening, and the proportion of patients that are on the referral and initial treatment. Evaluate clinician acceptance.
Company: PolyMedix, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 2
Abstract: DESCRIPTION (provided by applicant): Oral infections of Candida albicans represent an increasing problem in human health. In immunocompromised individuals, especially those suffering from AIDS, candiasis can result in both localized, yet painful lesions in the oral cavity as well as… more
Company: PolyMedix, Inc. Agency/Program/Year/Phase: DOD / STTR / 2010 / 2
Abstract: Multi-drug resistant (MDR) biofilms are one of the most difficult bacterial infections to treat. Current antibiotics are increasingly unable to cure these infections; underscoring the need to develop new antibiotics that operate through novel mechanisms which overcome the biofilm environment.… more
Company: PolyMedix, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Malaria is a global disease causing gt 500 million clinical cases and gt 1 million deaths each year. Moreover, drug resistant Plasmodium falciparum has become a major problem. Therefore, it is crucial to discover new c lasses of drugs for anti-malarial drug… more
Company: PolyMedix, Inc. Agency/Program/Year/Phase: NSF / SBIR / 2010 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I project is aimed at the development of antimicrobial sutures containing an active agent that displays broad activity against pathogens associated with surgical site infections (SSIs) and, via its unique mechanism of action, possesses a low… more
Company: PolyMedix, Inc. Agency/Program/Year/Phase: DOD / STTR / 2010 / 2
Abstract: Multi-drug resistant (MDR) biofilms are one of the most difficult bacterial infections to treat. Current antibiotics are increasingly unable to cure these infections; underscoring the need to develop new antibiotics that operate through novel mechanisms which overcome the biofilm environment.… more
Company: PROGENRA, INC. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Aberrant overactivation of WNT signaling appears to play a major role in Idiopathic Pulmonary Fibrosis (IPF). Inhibitors of overactivated WNT signaling are candidates for therapy of IPF. USP34, a novel de-ubiquitylating enzyme, has been identified as an IPF… more
Company: PROGENRA, INC. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Type 2 diabetes mellitus (T2D) has an enormous physical and economic impact worldwide. Despite current treatments, T2D often ultimately requires insulin replacement therapy and diminishes the patients' quality of life o wing to complications associated with… more
Company: PROGENRA, INC. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 2
Abstract: DESCRIPTION (provided by applicant): With the approval of the proteasome inhibitor Velcade for multiple myeloma therapy, the ubiquitin pathway has been validated for drug discovery. An alternative ubiquitin-associated degradation pathway is lysosomal; for example, the ubiquitin E3 ligase Cbl… more
Company: Propulsion Science and Technology, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2010 / 1
Abstract: The use of models to predict exhaust plume observables such as electro-optical (EO) signatures or radar cross section (RCS) is an integral part of many missile defense activities due to the limited quantity and extent of flight measurements on domestic and foreign missiles. The potential exists to… more
Company: Propulsion Science and Technology, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2010 / 1
Abstract: An effective missile defense will require an understanding of the combined radar signature of a hardbody and plume and a capability for predicting that signature. While there is a well developed technology and understanding of radar for the detection of missile hardbodies, the coherent radar… more
Company: ProtoInnovations, LLC Agency/Program/Year/Phase: NASA / STTR / 2010 / 1
Abstract: ProtoInnovations, LLC and Carnegie Mellon University have formed a partnership to commercially develop rover-autonomy technologies into Reliable Autonomous Surface Mobility (RASM). Our aim is to provide safe and reliable means for lunar rovers to travel at substantial speeds and operate in… more
Company: ProtoInnovations, LLC Agency/Program/Year/Phase: DOD / SBIR / 2010 / 1
Abstract: ProtoInnovations proposes to develop a versatile autonomous shipboard cleaning robot that we call the Multipurpose Automated Steward (MAS). Shipboard cleaning presents a complex environment with requirements to clean floors, walls, counters, and overheads in confined and fully three-dimensional… more
Company: Pulsar Informatics Inc. Agency/Program/Year/Phase: DOD / SBIR / 2010 / 1
Abstract: This project will achieve a handheld app to deliver the brief, 3-minute Psychomotor Vigilance Test (PVT) to provide immediate objective feedback to warfighters (and commanding officers) about their ability to sustain attention to mission critical tasks (e.g., route clearance, IED detection). It will… more
Company: Pulsar Informatics Inc. Agency/Program/Year/Phase: NASA / SBIR / 2010 / 2
Abstract: To ensure mission success, astronauts must maintain a high level of performance even when work-rest schedules result in chronic sleep restriction and circadian misalignment, both of which contribute to fatigue and performance deficits unless effective countermeasures are used. We are proposing to… more
Company: Pulsar Informatics Inc. Agency/Program/Year/Phase: NASA / SBIR / 2010 / 1
Abstract: Given the extended duration of future missions and the isolated, extreme and confined environments, there is the possibility that behavioral conditions and mental disorders (DSM-IV-TR) will develop. The overarching goal of this project is to deliver an Individualized Behavioral Health Monitoring… more
Company: Quantum Simulations, Inc. Agency/Program/Year/Phase: ED / SBIR / 2010 / 1
Abstract: This project will develop a web-based artificial intelligence software to target adult learners and remedial college students with math. To use the product students will enter their own problems and the software will automatically provide… more
Company: Quantum Simulations, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 2
Abstract: DESCRIPTION (provided by applicant): This Fast-Track application focuses on developing the first artificial intelligence (AI) educational software to teach developmental mathematics to the blind and visually impaired. This project responds to the National Eye Institute's General Research Topics for… more
Company: RDA Inc. Agency/Program/Year/Phase: DOD / SBIR / 2010 / 2
Abstract: The objective of this project is to develop a new means of detecting and classifying undersea targets in the return of active sonar waveforms, as well as in their forward scatter zone. The techniques under discussion cover an area of detection and classification that is currently un-attainable with… more
Company: RDA Inc. Agency/Program/Year/Phase: DOD / SBIR / 2010 / 2
Abstract: The Phase II implementation of the Sonobuoy Location System (SLS) utilizes existing sonobuoy RF signals to estimate the buoy positions. Using the techniques developed in Phase I, simulation of the SLS algorithm has provided sonobuoy position estimates well within the 100 yard accuracy requirement.… more
Company: RDA Inc. Agency/Program/Year/Phase: DOD / SBIR / 2010 / 1
Abstract: The Navy requires a new Environmental Wideband Acoustic Receiver and Source (EWARS) sensor to facilitate the gathering of environmental and intelligence and data from Navy ASW platforms. The newly developed EWARS sensor must be deployable in shallow and deep environments, and be capable of operating… more
Company: RDA Inc. Agency/Program/Year/Phase: DOD / SBIR / 2010 / 1
Abstract: Quick and accurate sonobuoy location is becoming more critical in the airborne ASW problem as multi-static search systems and data fusion techniques play more dominant roles. Sonobuoy locations must be determined quickly, and be constantly updated in order to estimate target locations as soon as… more
Company: RE2, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2010 / 1
Abstract: The challenges in the operations of small unmanned aircraft systems (SUAS) and micro air vehicles (MAVs) in terms of required agility and benign flying qualities require a superior understanding of their basic flight mechanics and vehicle dynamics. Flight test data for MAVs are sparse, and wind… more
Company: RE2, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2010 / 1
Abstract: The purpose of this project is to integrate RE2's innovative dexterous and heavy-lift manipulation technologies with novel materials and leading-edge actuation technology to provide a Highly Dexterous Manipulation System (HDMS) with 1) the strength to lift a 120-pound 155mm shell, 2) the agility to… more
Displaying 926 – 950 of 5210 Awards
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