Abstract:This Small Business Innovation Research Phase I project is directed towards adaptation of atom transfer radical polymerization (ATRP) to industrial scale production. ATRP is among the most powerful controlled/living radical polymerization techniques, and it is anticipated that many new products… more
Abstract:The primary objective of this proposed research effort is to develop an unconventional broadband infrared (IR) optical system for the advanced multi-functional, lower scattering loss, higher discrimination capability LADAR seeker and IR imager. The key innovation of the proposed system is… more
Abstract:The primary objective of this proposed research effort is to develop a novel laser eye protector (LEP) for visors, which can not only offer a high transmittance (over 85%) in the visible spectral range and a high blocking rate (OD 4) in the near IR spectral range but also be angular insensitive so… more
Abstract:Low visibility rotary aircraft decoys are needed to protect vehicles against heat seeking missile attacks without illuminating the target which exposes the aircraft to small arms fire and potentially compromising the mission. The novel approach to this challenge is to produce a decoy which emits… more
Abstract:The proposed effort addresses new concepts in terms of exploiting the thermobaric effect (increase of temperature and pressure) using variations of reactive materials which maximize energy release and gaseous by-products during impacts of low velocity (1-2
Abstract:DESCRIPTION (provided by applicant): The prevalence of insomnia reported in epidemiologic studies ranges from 10-40% of the population in the United States (30 to 120 million people) with similar rates reported worldwide. Hypnotics are the primary medical
treatment for insomnia, generating revenues… more
Abstract:DESCRIPTION (provided by applicant): Breast cancer is the most frequently diagnosed type of cancer in women, with 1.3 million new diagnoses and 465,000 deaths annually worldwide. There is an acute need for improved prognostic and predictive tools to aid in
dividualized treatment for breast cancer.… more
Abstract:Heat pipes are widely used for passive, two-phase electronics cooling. As advanced high power, high performance electronics in space based and terrestrial applications produce ever increasing heat fluxes, heat pipes with improved thermal capacity are sought. Illuminex Corporation has demonstrated… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Technology Transfer Phase I project will prototype a novel photovoltaic (PV) material based on nanotechnology: photovoltaic fabric. The PV fabric will be woven using threads that… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Innovation Research Phase I proposal will research, develop and demonstrate that the performance of Engineering Simulation and Modeling applications can be dramatically improved… more
Abstract:This Small Business Innovation Research Phase I project will address the problem of automating complex multi-step tasks and negotiations for computer users. The focus is on developing representations and algorithms for a personal assistant agent, and on contributing the incorporation of these… more
Abstract:DESCRIPTION (provided by applicant): Directxray Digital Imaging Technology (DXT) was formed in April of 2006, with a goal to introduce advanced technology developments for selenium detectors in x-ray imaging. We seek creative solutions to overcome the phys
ical limitations of existing selenium… more
Abstract:This project addresses two pressing problems in treating bacterial infections: the emerging resistance against current antibiotics and the role of biofilm formation in these infections. Based ona successful lead dendrimerthat acts against a broad spectrum of MDR pathogens including A.baumannii, and… more
Abstract:DESCRIPTION (provided by applicant): This is a Phase I proposal to develop a new family of imino sugars, with break through , unprecedented, potency, for the treatment of dengue virus (DENV) infection. There is currently no effective treatment for disease
s caused by this virus and both the public… more
Abstract:DESCRIPTION (provided by applicant): Novel Thioderivatives as Neuroprotective Anticonvulsants Abstract: The aim is to discover novel lead compounds that provide a disease- modifying therapeutic for the treatment of epilepsy. The ideal candidate molecules g
enerated by this program will exhibit both… more
Abstract:DESCRIPTION (provided by applicant): One sixth of the world's population has an infectious disease, and new agents involving novel mechanisms less likely to engender resistance are needed if for no other reason than the almost certain emergence of mutant s
trains and new pathogens in the future.… more
Abstract:This Small Business Innovation Research Phase I research project proposes to develop a smart wheelchair system that will integrate onboard LIDAR for position estimation and obstacle detection with an adaptive motor controller framework. The resulting smart-chair will be capable of autonomous… more
Abstract:The number of female farmers in the U.S. is on the rise, indicating a need for agricultural equipment that is safe and easy to use for women. Between 1997 and 2002, the total number of U.S. farms declined by almost 4%, yet the number of farms whose principal operators were women increased by 13%.… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project seeks to investigate the feasibility of a novel molten substrate fabricated from high-density liquids of metals/alloys and slags for producing high solar quality crystalline silicon wafer. In this innovative design a molten support… more
Abstract:There has been a great deal of development effort within the academic, governmental, and commercial arenas over the past few years in the field of information extraction. Based on our investigation, however, it appears that there is no ground truth for SIGACTS reports, which prevents GMTI users,… more
Abstract:DESCRIPTION (provided by applicant): Botulinum toxin is a potential bioweapon that can be used in acts of bioterrorism or biological warfare. Although the toxin is extraordinarily potent, there is little likelihood that there will be universal vaccination
of the public. This can be attributed to… more
Abstract:DESCRIPTION (provided by applicant): Most current chemotherapeutics are untargeted formulations that have little to no selectivity for cancerous tissue. As a result, these drugs often cause damage to healthy tissues which leads to uncomfortable and at time
s intolerable dose-limiting toxic side… more
Abstract:DESCRIPTION (provided by applicant): This project is designed to research and develop means for the early detection of impending roof falls in underground mines and means for alerting maintenance crews to take proactive action to prevent disaster, thereby
saving lives and preventing injuries to… more
Abstract:The objective of this proposal is to demonstrate the feasibility of an innovative thin-multilayer setback piezoelectric generator (TM-SPG) to provide inertial harvested power for spin stabilized small-and-medium-caliber fuzing. The novel setback generator uses the characteristics of piezoelectric… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Technology Transfer Phase I project proposes biologically inspired polymer fibrillar adhesives as new gripping materials for ultragrip sports glove and other potential gripping and… more
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